Stat4 (C46B10) Rabbit mAb 2653S from Cell Signaling Technology

Product Specs
ItemStat4 (C46B10) Rabbit mAb
CompanyCell Signaling Technology
Price $339.00 Inquire
Catalog Number2653S
Quantity100 µl
ApplicationsW, IP, ChIP, ChIP-seq
ReactivityH, M, R
TargetStat4
Molecular Weight81
HostRabbit
NCBI Gene AliasesSLEB11
ClonalityMonoclonal
NCBI Full Gene Namesignal transducer and activator of transcription 4
CloneC46B10
Research AreaImmunology and Inflammation

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Cell Signaling Technology

3 Trask Lane

Danvers, Massachusetts 01923

United States

Phone: 877-616-CELL
Phone: 978-867-2388
Fax: 866-432-6112
Fax: 978-867-2488

Company Profile

Website: http://www.cellsignal.com/

Website: Technical Support

(1) Sphingosine-1-Phosphate Receptor 3 Confers Tumor Metastasis in Lung Cancer Resistant to Third-Generation EGFR InhibitorMedComm (2020)April 23, 2026Mengzhen Lai, Jiaying Chen, Ye Qin, Hui Zhang, Zilu Pan, Tao Zhang, Linjiang Tong, Haotian Tang, Gang Bai, Qiupei Liu, et al.(CST, #70512S), E‐cadherin (CST, #3195S), fibronectin (CST, #26836S), FGFR1 (CST, #9740S), STAT4 (CST, #2653S), and actin (Proteintech, 60008‐1‐Ig) at 4°C overnight and then incubated with secondary antibodies

(2) PTPN1/PTPN2 inhibition improves NK cancer therapy by enhancing IL-2 and mitigating TGFβ1 responsesEMBO ReportsApril 15, 2026Chu-Han Feng, Linda Peltier, Tiffanie Chouleur, Milea DiPonzio, Isabelle Aubry, Alexandre J Poirier, Zuzet M Cordova, Yunyun Shen, Sébastien Tabariès, Xiaona Cao, et al.1:1000",Cell Signaling Technology,9131 "STAT4 (Clone C46B10) – Rabbit, 1:1000",Cell Signaling Technology,2653 "p-STAT4 (Y693) (Clone Polyclonal) – Rabbit, 1:1000",Cell Signaling Technology,5267 "STAT5 (Clone

(3) CD30 knockout attenuates experimental colitis by reducing inflammatory cytokine productionBMC ImmunologyMarch 13, 2026Lili Guo, Zhaocai He, Changqing Yang, Xiaorong Chen, Juan WangNo. ab91109; Abcam, Cambridge, MA, USA), anti-IFN-γ (Cat. No. ab9657; Abcam), anti-STAT4 (Cat. No. 2653; Cell Signaling Technology, Danvers, MA, USA), anti-phospho-STAT4 (Tyr693) (Cat. No. 4134; Cell Signaling Technology

(4) Multi-omics analysis reveals the association of cesarean delivery with altered gut microbial profiles and a Th2-biased immune response in neonatesJournal of Translational MedicineMarch 11, 2026Chunhui Lai, Jiangang Zhang, Yu Xiong, Yijin Wang, Zhenxing Liu, Mingfang Shi, Shenglin Ye, Jianghui Zengproteins were transferred to a membrane, blocked, and probed with primary antibodies against STAT4 (Cat# 2653T, CST, USA) and STAT6 (Cat# 5397T, CST, USA), followed by incubation with appropriate HRP-conjugated

(5) STAT-independent functions of Janus kinases 1 and 2 are obligatory for the postnatal development of mammary epithelial ductsCell ReportsJanuary 27, 2026Rayane Dennaoui, Madison N. Wicker, Carson Moen, Michaela Schlederer, Kerry Vistisen, Aleata A. Triplett, Thomas Rülicke, Hallgeir Rui, Lukas Kenner, Emilio Casanova, et al.monoclonal, STAT2",Cell Signaling,Cat#72604; RRID:AB_2799824 "Rabbit monoclonal, STAT4",Cell Signaling,Cat#2653; RRID:AB_ 2255156 "Chicken polyclonal, GFP",Aves Labs,Cat#GFP-1020; RRID:AB_10000240 "Rat monoclonal,

(6) IL-12 ameliorates diabetic retinal neurodegeneration by activating microglial phagocytosis via the TREM2/DAP12 pathwayMolecular NeurobiologyJanuary 1, 2026Wanyi Fang, Shanshan Liu, Yifei Wu, Ting Chen, Xiaohe Lu, Hui Chen(1/200),Abcam,ab283319,17kDa Anti-TREM2,WB(1/1000),Bioss,bs-2723R,33kDa Anti-TYROBP,WB(1/1000),Bioss,bs-12630R,12kDa Anti-β-actin,WB(1/1000),Fude,FD0060,42kDa Anti-p-STAT4,WB(1/500),Santa cruz,sc-136194,89kDa Anti-STAT4,WB(1/1000),CST,2653S,89kDa "Goat anti-Rabbit IgG (H + L) Cross-Adsorbed ReadyProbes Secondary Antibody, Alexa Fluor 488",IHC(1/300)ICC

(7) TRP75-mediated STAT3 activation promotes anti-apoptotic signaling and Ehrlichia chaffeensis infectionInfection and ImmunityNovember 11, 2025Nicholas A. Pittner, Jaclyn R. McCoy, Duc-Cuong Bui, Jere W. McBrideCell Signaling Technology), rabbit α-STAT3 (12640S; Cell Signaling Technology), monoclonal rabbit α-STAT4 (2653S; Cell Signaling Technology), monoclonal rabbit α-STAT5 (94205S; Cell Signaling Technology), monoclonal

(8) Chidamide suppresses macrophage-mediated immune evasion and tumor progression in small cell lung cancer by targeting the STAT4/CCL2 signaling pathwayCancer Biology & MedicineOctober 23, 2025Wenting Liu, Ting Mei, Yantao Jiang, Jingya Wang, Mengjie Li, Liuchun Wang, Zhaoting Meng, Tingting Qin, Dingzhi HuangCST); HDAC3 (#85057, 1:1000; CST); HDAC10 (ab108934, 1:000; Abcam, Cambridge, MA, USA) and STAT4 (#2653S, 1:1000; CST). Finally, enhanced chemiluminescence reagent (Millipore) was used to detect protein bands

(9) Uncovering the individual immunotherapeutic roles of PTPN1 and PTPN2 in T cells during dual inhibitioniScienceOctober 17, 2025Luis-Alberto Perez-Quintero, Alexandre J. Poirier, Chu-Han Feng, Zuzet Martinez-Cordoba, Isabelle Aubry, Cedric Carli, Samaneh Kamyabiazar, Alain Pacis, Yevgen Zolotarov, Kelly-Anne Pike, et al.Cell Signalling Technologies IRF4 (Cat#4948; P173), STAT1 (Cat#9172T), STAT3 (Cat#4904), STAT4 (Cat#2653), STAT5a (Cat#94205), STAT6 (Cat#5397), pSTAT1 Y701 (Cat#7649), pSTAT3 Y705 (Cat#9131), pSTAT4 Y693(Cat#5267),

(10) Cold Urticaria: From Wheals to AnaphylaxisAllergy, Asthma & Immunology ResearchSeptember 24, 2025Mojca Bizjakis applied to the volar (flexor) forearm for 5 minutes, followed by a 10-minute observation period.2653 Typical ColdU is characterized by palpable whealing at the site of standard CST, appearing within this

(11) Improving CAR-T cell function through a targeted cytokine delivery system utilizing car target-modified extracellular vesiclesExp Hematol OncolAugust 25, 2025Yuanyuan Zhang, Meijuan Huang, Shujia Zhang, Tianjiao Liu, Shanwei Ye, Yuhang Cheng, Yang Cao, Liting Chen, Li Zhu, Xueyan Sun, et al.STAT4 and phosphorylated STAT4 in T cells were detected using an anti-Stat4 (C46B10) antibody (CST, 2653 S, 1:1000) and an anti-phospho-Stat4 (Tyr693) antibody (CST, 5267 S, 1:1000). After three washes with

(12) Opposing regulation of TNF responses by IFN-γ and a PGE2-cAMP axis that is apparent in rheumatoid and immune checkpoint inhibitor-induced arthritis human IL-1β+ macrophagesElifeJuly 15, 2025Upneet K Sokhi, Ruoxi Yuan, Bikash Mishra, Yurii Chinenov, Anvita Singaraju, Karmela K Chan, Anne Bass, Richard D Bell, Laura Donlin, Lionel B IvashkivCell Signaling Technology (cat# 9212) and Stat4 antibodies (C46B10 rabbit mAb) were from Cell Signaling Technology (cat# 2653). Membranes were washed three times with TBST and probed with anti-rabbit IgG secondary antibodies conjugated

(13) Opposing regulation of TNF responses by IFN-γ and a PGE2-cAMP axis that is apparent in rheumatoid and immune checkpoint inhibitor-induced arthritis human IL-1β+ macrophagesElifeJuly 15, 2025Upneet K Sokhi, Ruoxi Yuan, Bikash Mishra, Yurii Chinenov, Anvita Singaraju, Karmela K Chan, Anne R Bass, Richard D Bell, Laura Donlin, Lionel B IvashkivCell Signaling Technology (cat# 9212) and Stat4 antibodies (C46B10 rabbit mAb) were from Cell Signaling Technology (cat# 2653). Membranes were washed three times with TBST and probed with anti-rabbit IgG secondary antibodies conjugated

(14) Memory T-Cell Phenotype in Cutaneous T-Cell Lymphoma Is Modified by Germline Gene Gametocyte Specific Factor 1Exp DermatolMay 14, 2025Amelia Martínez Villarreal, Jennifer Gantchev, Pingxing Xie, Philippe Lefrançois, Brandon Ramchatesingh, Ivan V. Litvinov9145 RRID:AB_2491009), STAT3 (Cell Signaling Cat# 30835 RRID:AB_2798995), STAT4 (Cell Signaling Cat# 2653, RRID:AB_2255156), STAT5 (Cell Signaling Cat# 94205 RRID:AB_2737403), pSTAT6 (Cell Signaling Cat# 9361

(15) Identification of a JAK–STAT–miR155HG positive feedback loop in regulating natural killer (NK) cells proliferation and effector functionsActa Pharmaceutica Sinica BMarch 2, 2025Songyang Li, Yongjie Liu, Xiaofeng Yin, Yao Yang, Xinjia Liu, Jiaxing Qiu, Qinglan Yang, Yana Li, Zhiguo Tan, Hongyan Peng, et al.(5031t), human phospho-Y705 of STAT3 (9145T), STAT3 (4904S), phospho-Y693 of STAT4 (4134S), STAT4 (2653S), phospho-Y694 of STAT5 (9359S), STAT5 (94205S), GAPDH (8884S) from Cell Signalling Technology (CST,

(16) Dimeric natural product panepocyclinol A inhibits STAT3 via di-covalent modificationActa Pharmaceutica Sinica BJanuary 1, 2025Li Li, Yuezhou Wang, Yiqiu Wang, Xiaoyang Li, Qihong Deng, Fei Gao, Wenhua Lian, Yunzhan Li, Fu Gui, Yanling Wei, et al.(Cat# 9139), phospho-STAT3 (Tyr705) (Cat# 9131), STAT1 (Cat# 14994), STAT2(Cat# 72604), STAT4 (Cat# 2653), STAT5 (Cat# 9363S), STAT6 (Cat# 5397) were purchased from Cell Signaling Technology (CST) and used

(17) Aiolos promotes CXCR3 expression on Th1 cells via positive regulation of IFN-γ/STAT1 signalingJCI insightNovember 19, 2024Leonard MR, Jones DM, Read KA, Pokhrel S, Tuazon JA, Warren RT, Yount JS, Oestreich KJ.Cell Signaling Technology), α–pY-STAT4 (1:1,000; 5267, Cell Signaling Technology), α-STAT4 (1:1,000; 2653S, Cell Signaling Technology), α–pY-STAT1 (1:1,000; 9167S, Cell Signaling Technology), α-STAT1 (1:1,000;

(18) Phenotypic profiling of human induced regulatory T cells at early differentiation: insights into distinct immunosuppressive potentialCellular and molecular life sciences : CMLSSeptember 12, 2024Kattelus R, Starskaia I, Lindén M, Batkulwar K, Pietilä S, Moulder R, Marson A, Rasool O, Suomi T, Elo LL, et al.(Thermo Fisher Scientific Cat# 14-4776-82, RRID: AB_467554), anti-human STAT4 antibody (Cell Signaling Technology Cat# 2653, RRID: AB_2255156), anti-human PRDM1 antibody (Cell Signaling Technology Cat# 9115, RRID: AB_2169699),

(19) STAT4 Mediates IL-6 Trans-Signaling Arrhythmias in High Fat Diet Guinea Pig HeartInternational Journal of Molecular SciencesJuly 17, 2024Andrea Corbin, Kelly A. Aromolaran, Ademuyiwa S. AromolaranCell Signaling, Danvers, MA, USA, RRID:AB_10545446); 1:50 dilution of anti-Stat4 (C46B10) rabbit pAb (#2653, Cell Signaling, Danvers, MA, USA, RRID:AB_22551556); 1:50 dilution of anti-IL-18 (D2F3B) rabbit pAb

(20) Genome-wide p63-Target Gene Analyses Reveal TAp63/NRF2-Dependent Oxidative Stress ResponsesCancer Res CommunFebruary 1, 2024Napoli M, Deshpande AA, Chakravarti D, Rajapakshe K, Gunaratne PH, Coarfa C, Flores ER.(ab190226, Abcam, RRID:AB_2941798), Nrf2 (#12721, Cell Signaling Technology, RRID:AB_2715528), Stat4 (#2653, Cell Signaling Technology, RRID:AB_2255156), and Stat5a (#9363, Cell Signaling Technology, RRID:AB_2196923).

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Stat4 (C46B10) Rabbit mAb

Stat4 (C46B10) Rabbit mAb from Cell Signaling Technology

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Cell Signaling Technology

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Stat4 (C46B10) Rabbit mAb from Cell Signaling Technology

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