LC3A/LC3B Antibody PA1-16931 from Thermo Fisher Scientific

Product Specs
ItemLC3A/LC3B Antibody
CompanyThermo Fisher Scientific
Price Supplier Page
Catalog NumberPA1-16931
NCBI Gene Aliaseszgc:56434, zgc:77094, Mpl3, wu:fb60g11, LC3, MAP1BLC3, 1010001C15Rik, MAP1A/1BLC3, LC3-I, MAP1ALC3, MAP1LC3B-a, Map1lc3, zbs559, LC3-II, LC3B, MAP1A/MAP1B, LC3A, ATG8E, 4922501H04Rik, LC3b, LC3a, ATG8G, ATG8F, Atg8, 1010001H21Rik
ClonalityPolyclonal
HostRabbit
Conjugate/TagUnconjugated
ApplicationsChIP Assay, Immunocytochemistry, Immunohistochemistry (Frozen), Immunoprecipitation, Western Blot
TargetLC3A/LC3B
FormatPBS with 0.02% sodium azide
ReactivityAmphibian, Bovine, Canine, Fish, Human, Mouse, Plant, Rat, Zebrafish
Quantity100 µL
NCBI Full Gene Namemicrotubule-associated protein 1 light chain 3 alpha, microtubule-associated protein 1 light chain 3 beta, microtubule associated protein 1 light chain 3 beta, microtubule associated protein 1 light chain 3 beta 2, microtubule-associated protein 1 light chain 3 beta 2, microtubule associated protein 1 light chain 3 alpha
Concentration1 mg/mL
ImmunogenSynthetic peptide made to an internal portion of the human LC3 protein sequence (between residues 25-121)
IsotypeIgG
Storage Temperature-20°C or -80°C if preferred
PurityAntigen affinity chromatography
Antibody TypePrimary
Storage-20°C or -80°C if preferred

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Website: www.thermofisher.com

(1) Does Enriched Environment Improve Chronic Immobilization Stress-Induced Cognitive and Behavioral Changes in Adult Male Rats?Cell Mol NeurobiolApril 12, 2026Mona A. Mohammed, Amira S. Ahmed, Fatma M. M. Salem, Eman S. H. Abd Allahantibody for light chain 3 A and B (LC3A/LC3B) antibody for the detection of autophagosomes (Catalog # PA1-16931) purchased from Thermo Scientific, USA. The primary antibody was a rabbit polyclonal antibody using

(2) Octreotide attenuates intestinal ischemia/reperfusion mischief in rats through modulation of Nrf2/PRX2/ASK1/JNK signaling pathwayNaunyn-Schmiedeberg's archives of pharmacologyNovember 1, 2025El Sayed NF, Ragab D, Abdo W, Ghoneim ME.(Cell Signaling Technology, USA, Cat# 9251, dilution 1:1000); LC3 (ThermoFisher Scientific, USA, Cat # PA1 - 16931, dilution 1:1000); β-actin (Cell Signaling Technology, USA, dilution 1:1000). The membrane was then

(3) Boric Acid Suppresses Cell Survival by Triggering Endoplasmic Reticulum Stress-Induced Autophagy in Cervical CancersJ Cell Mol MedJuly 19, 2025Betul Keyif, Ceyhan Hacioglu(CDK4) (1:2500, PA5‐27827, Invitrogen), Beclin1 (1:1000, PA1‐16857, Invitrogen), LC3‐I/II (2 μg/mL, PA1‐16931, Invitrogen), p62 (1 μg/mL, P0067, Sigma‐Aldrich), GRP78 (2 μg/mL, PA1‐014A, Invitrogen), p‐PERK (1:1000,

(4) Impact of LITAF on Mitophagy and Neuronal Damage in Epilepsy via MCL-1 UbiquitinationCNS neuroscience & therapeuticsJanuary 1, 2025Min F, Dong Z, Zhong S, Li Z, Wu H, Zhang S, Zhang L, Zeng T.(Mouse),Thermofisherr,PA5‐96333,1:1000 PINK1 (Mouse),Thermofisherr,PA1‐16604,1:500 LC3‐I/LC3‐II (Mouse),Thermofisherr,PA1‐16931,1:500 TIMM23 (Mouse),Thermofisherr,MA5‐27384,1:1000 TOMM20 (Mouse),Thermofisherr,PA5‐52843,1:250 GAPDH

(5) Renogrit selectively protects against cisplatin-induced injury in human renal tubular cells and in Caenorhabditis elegans by harmonizing apoptosis and mitophagyScientific reportsAugust 21, 2024Balkrishna A, Gohel V, Pathak N, Joshi M, Singh R, Kumari A, Dev R, Varshney A.(LXR-α),H00010062-M08,MA131-3E9 ERK1/ERK2,13-6200,UG286805 p-ERK1/p-ERK1,36-8800,VB2933212 JNK1/JNK2,AHO1362,RA23154 p-JNK1/p-JNK2,44-682G,2259453 p38,MA5-15116,WA3165876 p-p38,44-684G,2249202 LC3A/LC3B,PA1-16931,WF3308803A p-PINK-1,PA5-105356,YD3880896A β-actin,MA5-11869,XE3585078 List of antibodies used for western blotting

(6) Burkholderia pseudomallei BipD modulates host mitophagy to evade killingNature communicationsJune 4, 2024Nan D, Rao C, Tang Z, Yang W, Wu P, Chen J, Xia Y, Yan J, Liu W, Zhang Z, et al.

(7) Effects of Reduced Extracellular Sodium Concentrations on Cisplatin Treatment in Human Tumor Cells: The Role of AutophagyInternational journal of molecular sciencesApril 16, 2024Naldi L, Fibbi B, Anceschi C, Nardini P, Guasti D, Peri A, Marroncini G.membranes were incubated with specific primary antibodies as follows: rabbit monoclonal anti-LC3AB (1:500, PA1-16931, Thermo Fisher Scientific, Waltham, MA, USA), mouse monoclonal anti-beclin 1 (1:1000, D40C5, Cell Signaling

(8) Effect of Blueberry Supplementation on a Diet-Induced Rat Model of Prediabetes-Focus on Hepatic Lipid Deposition, Endoplasmic Stress Response and AutophagyNutrientsFebruary 13, 2024Ferreira G, Vieira P, Alves A, Nunes S, Preguiça I, Martins-Marques T, Ribeiro T, Girão H, Figueirinha A, Salgueiro L, et al.h Anti-SQSTMI/p62,5114S,Cell Signaling Technology,Rabbit,5% BSA in TBS-T,1% BSA in TBS-T,1:1000,24 h Anti-LC3,PA1-16931,Thermo Fisher Scientific,Rabbit,5% BSA in TBS-T,1% BSA in TBS-T,1:1000,24 h Loading Controls,Loading

(9) Intra-tumor ROS amplification by melatonin interferes in the apoptosis-autophagy-inflammation-EMT collusion in the breast tumor microenvironmentHeliyonJanuary 15, 2024Das N, Mukherjee S, Das A, Gupta P, Bandyopadhyay A, Chattopadhyay S.(ab109268), Twist (ab49254) from abcam (Cambridge, UK); H3B (PA5-22388), beta-actin (MA5-15739), LC3A/LC3B (PA1-16931), p-STAT3 (Tyr705) (MA5-15193), Cleaved caspase 3 (PA5-64749) from ThermoFisher Scientific (Waltham,

(10) Immunohistochemical Expression of Autophagy-Related Marker (LC3B) and Stem Cell Marker (CD44) in Molecular Subtypes of Breast CancerAsian Pacific journal of cancer prevention : APJCPJanuary 1, 2024El-Deek HEM, El-Naggar MS, Sayed SG.

(11) Update on a brain-penetrant cardiac glycoside that can lower cellular prion protein levels in human and guinea pig paradigmsPloS oneJanuary 1, 2024Eid S, Zhao W, Williams D, Nasser Z, Griffin J, Nagorny P, Schmitt-Ulms G.

(12) Infliximab Ameliorates Methotrexate-Induced Nephrotoxicity in Experimental Rat Model: Impact on Oxidative Stress, Mitochondrial Biogenesis, Apoptotic and Autophagic MachineriesCell biochemistry and biophysicsDecember 1, 2023Wasfey EF, Shaaban M, Essam M, Ayman Y, Kamar S, Mohasseb T, Rozik R, Khaled H, Eladly M, Elissawi M, et al.(Elabscience, Cat# E-AB-53242) and rabbit LC-3 Polyclonal antibody (Thermo-Fisher Scientific, Cat# PA1-16931), immunohistochemical staining was performed according to the manufacturer’s protocol. Immunohistochemical

(13) Elucidating the molecular mechanisms underlying the induction of autophagy by antidepressant-like substances in C57BL/6J mouse testis model upon LPS challengeCell communication and signaling : CCSSeptember 21, 2023Sołek P, Czechowska E, Sowa-Kućma M, Stachowicz K, Kaczka P, Tabęcka-Łonczyńska A.PA5-23186, RRID: AB_2540712), anti-ATG16L1 (1:1000; #PA1-46307, RRID: AB_2059398), anti-LC3A/B (1:1000, #PA1-16931, RRID: AB_2137583) (Thermo Scientific, Saint Louis, MO, USA) or anti-BCl2 (1:500; #sc-7382, RRID:AB_626736;

(14) Optogenetically engineered Ca2+ oscillation-mediated DRP1 activation promotes mitochondrial fission and cell deathJournal of cell scienceJune 15, 2023Lai YS, Chang CC, Chen YY, Nguyen TMH, Xu J, Chen YC, Chang YF, Wang CY, Chen PS, Lin SC, et al.(0.1 M Tris, 1 M NaCl and 0.05% Tween-20, pH 7.6); Invitrogen, MA3-024], anti-LC3 (1:1000; Invitrogen, PA1-16931), anti-phospho-ERK1/2 (1:1000; arigo Biolaboratories, ARG52277, Taiwan), anti-ERK2 (1:1000; arigo Biolaboratories,

(15) Accumulation of α-synuclein mediates podocyte injury in Fabry nephropathyThe Journal of clinical investigationJune 1, 2023Braun F, Abed A, Sellung D, Rogg M, Woidy M, Eikrem O, Wanner N, Gambardella J, Laufer SD, Haas F, et al.(Sigma-Aldrich, T9026), actinin 4 (Abcam, ab108198), p62 (Cell Signaling Technology, 5114), LC3 (Invitrogen, PA1-16931), SNCA (Santa Cruz Biotechnology, sc-12767), SCARB2 (Lifespan Biosciences, LS-B3225-0.05), TTYH3 (Origene,

(16) Metformin preconditioning protects against myocardial stunning and preserves protein translation in a mouse model of cardiac arrestJ Mol Cell Cardiol PlusJune 1, 2023Rutledge CA, Lagranha C, Chiba T, Redding K, Stolz DB, Goetzman E, Sims-Lucas S, Kaufman BA.(1:5000, Millipore, St. Louis, MO, #AB2302), p62 (1:1000, Sigma-Aldrich, #P0067), LC3 (Invitrogen, 1:1000, PA1–16931), OxPhos Rodent Antibody Cocktail 1:5000 (ThermoFisher, #458099), OPA1 (Invitrogen, 1:1000, PA5–57875),

(17) Diets Differently Regulate Tumorigenesis in Young E0771 Syngeneic Breast Cancer Mouse ModelJournal of clinical medicineJanuary 4, 2023Thangavel H, Lizardo K, Dhanyalayam D, De Assis S, Nagajyothi JF.Immunohistochemistry (IHC) was performed on tumor sections using rabbit polyclonal LC3A/LC3B antibody (#PA1-16931, Invitrogen, Waltham, MA, USA) and rabbit polyclonal Annexin V antibody (#8555, Cell Signaling Technology,

(18) Inhibition of Ubiquitin-Specific Protease-13 Improves Behavioral Performance in Alpha-Synuclein Expressing MiceInternational journal of molecular sciencesJuly 23, 2022Liu X, Balaraman K, Lynch CC, Hebron M, Shah PK, Hu S, Stevenson M, Wolf C, Moussa C.PA3-16717, Rockford, IL, USA). LC3-I and LC3-II were probed with polyclonal antibody (Thermo Fisher, PA1-16931, Rockford, IL, USA). WBs were quantified by densitometry using Quantity One 4.6.3 software (Bio Rad,

(19) Cx43-mediated sorting of miRNAs into extracellular vesiclesEMBO reportsJuly 5, 2022Martins-Marques T, Costa MC, Catarino S, Simoes I, Aasen T, Enguita FJ, Girao H.

(20) Mitochondrial rRNA Methylation by Mettl15 Contributes to the Exercise and Learning Capability in MiceInternational journal of molecular sciencesMay 27, 2022Averina OA, Laptev IG, Emelianova MA, Permyakov OA, Mariasina SS, Nikiforova AI, Manskikh VN, Grigorieva OO, Bolikhova AK, Kalabin GA, et al.Cell Signaling Technology, Danvers, MA, USA), pAKT (Thr308) (4056, Cell Signaling Technology, Danvers, MA, USA), LC3A/B (PA1-16931, ThermoFisher Scientific, Waltham, MA, USA), SDHB (PA5-29843, ThermoFisher Scientific, Waltham, MA,

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LC3A/LC3B Antibody

LC3A/LC3B Antibody from Thermo Fisher Scientific

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LC3A/LC3B Antibody from Thermo Fisher Scientific

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