SLC7A11 Antibody PA1-16893 from Thermo Fisher Scientific

Product Specs
ItemSLC7A11 Antibody
CompanyThermo Fisher Scientific
Price Supplier Page
Catalog NumberPA1-16893
NCBI Gene Aliasessut, CCBR1, xCT, 9930009M05Rik
ClonalityPolyclonal
Quantity100 µL
ReactivityHuman, Mouse, Rat
FormatPBS with 0.02% sodium azide
TargetSLC7A11
HostRabbit
Conjugate/TagUnconjugated
ApplicationsFlow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), In Situ Hybridization, Western Blot
NCBI Full Gene Namesolute carrier family 7 member 11, solute carrier family 7 (cationic amino acid transporter, y+ system), member 11
Concentration1 mg/mL
ImmunogenSynthetic peptide made to an N-terminal region of the human xCT protein (between residues 1-50)
IsotypeIgG
PurityAntigen affinity chromatography
Antibody TypePrimary
StorageStore at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles

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Thermo Fisher Scientific

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Waltham, MA 02451

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Website: www.thermofisher.com

(1) MYLK4 promotes colorectal cancer progression by regulating lipid metabolism reprogramming via targeting ferroptosisNeoplasiaMarch 1, 2026Bishi Wang, Kongxiu Wu, Xin Liu, Yuhai Shen, Yanliang Li1/1000-1/1500 dilutions). Thermo Fisher Scientific (Shanghai, China) provided the antibodies against SLC7A11 (#PA1-16893; 1/1000 dilutions) and MYLK4 (#PA5-100622 and #PA5-25869, 1/150-1/1000 dilutions). Furthermore, Santa Cruz Biotechnology

(2) Ferroptosis is a novel pathogenic mechanism of FDXR-related disease via disruption of the NRF2 pathwayCell Death DiscovDecember 23, 2025Teresa Campbell, Jesse Slone, Jimmy Vu, Wensheng Liu, Li Yang, Adam Dourson, Luis F. Queme, Michael P. Jankowski, Taosheng Huanganti-FDXR (ab204310, Abcam) at 1:1000 dilution. For staining SLC7A11 protein, rabbit anti-SLC7A11 (PA1-16893 Thermo Fisher) was used at 1:1000 dilution for staining mouse tissues, and rabbit anti-SLC7A11 (12691,

(3) Inhibition of mettl3-mediated m6a rna modification of HMGCS1 protects retinal ganglion cells from glutamate excitotoxicity-induced ferroptosis in a rat model of glaucomaInternational Journal of SurgeryDecember 1, 2025Chao Wang, Lemeng Feng, Weizhou Fang, Cheng Zhang, Wulong Zhang, Weiming Zhu, Ye He, Zhaohua Xia, Weitao Song, Xiaobo Xia4°C: beta-actin monoclonal antibody (# 66009-1-Ig; Proteintech; 1:1000), SLC7A11 Polyclonal Antibody (#PA1-16893; Thermofisher; 1:1000), HMGCS1 Polyclonal antibody (#17643-1-AP; Proteintech; 1:1000), glutathione peroxidase

(4) Therapeutic effects of Bushen Chushi formula on knee osteoarthritis via modulation of MAPK/SLC7A11/GPX4 signaling in ratsHereditasOctober 29, 2025Yuanyuan Li, Hai Tang, Mingjiang He, Xinyue Wang, Yanbai Chen, Siye Liu, Hongmei Zhangthe following primary antibodies were applied: SLC7A11 Polyclonal Antibody (Thermo Fisher Scientific, PA1-16893, 1:200), GPX4 Polyclonal Antibody (Proteintech, 30388-1-AP, 1:200), and MMP-13 Polyclonal Antibody (Proteintech,

(5) Renoprotective Effects of MIT-001 in Ischemia-Reperfusion Injury: Modulation of Ferroptosis, ROS and Fibrotic MarkersJ Cell Mol MedOctober 22, 2025Jin Ah Shin, Yunkyeong Hwang, Hyerim Park, Hyunsu Choi, Yoon-Kyung Chang, Ki Ryang Na, Soon Ha Kim, Jae Young Kim, Young Rok Ham, Dae Eun ChoiBiotechnology, Dallas, TX, USA), HO‐1 (1:1000, SPA‐895: Enzo Life Sciences, Vienna, Austria) and xCT (1:1000, PA1‐16893: Invitrogen, Waltham, MA, USA). The membranes were incubated with horseradish peroxidase–conjugated

(6) Identifying a role for oxytosis/ferroptosis in Pde6b-associated retinitis pigmentosaExperimental Eye ResearchAugust 1, 2025Madison E. Weiss, Paola E. Parrales, Maumita Datta, Michelle Fleishaker, Galina Dvoriantchikova, Dmitry Ivanov, Abigail S. HackamDifferential expression of Gpx4 (#52455, Cell Signaling Technology, Danvers, MA, USA) and Slc7a11 (PA1–16893, Thermo Fisher Scientific, Waltham, MA, USA) was confirmed by Western blotting (Gapdh [GTX627408, GeneTex,

(7) Exploration of the role and mechanism of Rhizoma Paridis total saponins in osteosarcoma based on SPI1/LCN2-mediated ferroptosisFrontiers in OncologyJune 25, 2025Ge Yang, Fenghui Li, Xiongke Hu, Miao Li, Yaoxi Liu, Guanghui Zhu, Qian Tanhour, followed by overnight incubation at 4°C with primary antibodies, including anti-SLC7A11 (1:1,000, PA1-16893, Thermo Fisher Scientific), anti-GPX4 (1:10,000, MA5-32827, Thermo Fisher Scientific), anti-LCN2 (1:1,000,

(8) Endoplasmic reticulum-mitochondria contacts are prime hotspots of phospholipid peroxidation driving ferroptosisNat Cell BiolJune 13, 2025Maria Livia Sassano, Yulia Y. Tyurina, Antigoni Diometzidou, Ellen Vervoort, Vladimir A. Tyurin, Sanket More, Rita La Rovere, Francesca Giordano, Geert Bultynck, Benjamin Pavie, et al.polyclonal VDAC1 (Cell Signaling, 4866S; 1:1,000); rabbit polyclonal anti SLC7A11 (Thermo Fisher Scientific, PA1-16893, 1:1,000). The reagents used were: Bodipy 581/591 C11 (Thermo Fisher Scientific); Liperfluo (Dojindo),

(9) PF4 regulates neuronal ferroptosis in cerebral hemorrhage through CXCR3/PI3K/AKT/Nrf2 pathwayBiomolecules and BiomedicineJune 1, 2025Na Hu, Yunfeng Li, Guohong Zhang, Wei Wang, Liping An, Ran An, Yu Liufamily member 4 (ACSL4, PA5-27137, 1:500, Invitrogen), Solute carrier family 7 member 11 (SLC7A11, PA1-16893, 1:1000, Invitrogen), Cyclooxygenase-2 (COX-2, 35–8200, 1:100, Invitrogen), p-PI3K (PA5-104853, 1:1000,

(10) Gastrodia protects HT22 cells from damage caused by oxygen glucose deprivation and reperfusion through inhibiting ferroptosisSci RepMay 27, 2025Dongyue Zhou, Zhixuan Huang, Jian Liu, Jinlong Tan, Hui Li, Yangwen Aimembrane, placed at a temperature of 4℃ for an overnight incubation with SLC7A11 primary antibody (PA1-16893, 1:1000, Invitrogen), acyl-CoA synthetase long-chain family member 4 (ACSL4) primary antibody (PA5-27137,

(11) circFADS2 inhibits ferroptosis associated with IGF2BP2-dependent SLC7A11 m6A modification in colorectal cancer cellsJournal of Gastrointestinal OncologyApril 30, 2025Liangjun Jiang, Xianzhou Lu, Wei Lithe membrane was sealed with 5% skimmed milk powder for 1 hour. Following blocking, SLC7A11 (1:1,000, PA1-16893, Thermo Fisher Scientific) and GAPDH (1:5,000, MA5-35235, Invitrogen) antibodies were added to treat

(12) Epigenetic mechanisms of Nsd1-mediated histone methylation modifications in chondrocyte ferroptosis in knee osteoarthritisBiomol BiomedMarch 7, 2025Wang R, Shi D, Pan X, Ren A, Jiang K.ab155282, Abcam), SOX9 (1:1000, 702016, Invitrogen), solute carrier family 7 member 11 (SLC7A11) (1:1000, PA1-16893, Invitrogen), and MMP13 or β-actin (1:5000, ab8227, Abcam). After incubation with secondary antibodies

(13) Knockdown of Gfi1 increases BMSCs exosomal miR-150-3p to inhibit osteoblast ferroptosis in steroid-induced osteonecrosis of the femoral head through BTRC/Nrf2 axisEndocrine journalFebruary 3, 2025Zheng L, Zhang C, Liao L, Hai Z, Luo X, Xiao H.(BSA) and incubated with primary antibodies overnight at 4°C: GPX4 (ab125066, 1:1,000, Abcam), SLC7A11 (PA1-16893, 1:1,000, Invitrogen), ACSL4 (ab155282, 1:1,000, Abcam), BTRC (37-3400, 1:1,000, Invitrogen), and Nrf2

(14) Lycopene Ameliorates Polycystic Ovary Syndrome in Rats by Inhibiting Ovarian Ferroptosis Through Activation of the AMPK/Nrf2 PathwayJournal of biochemical and molecular toxicologyFebruary 1, 2025Wang K, Wang L, Wu C, Chen H, Cai D, Lu L, Liu X, Jiao Z.

(15) Astrocytic HIV-1 Nef Expression Decreases Glutamate Transporter Expression in the Nucleus Accumbens and Increases Cocaine-Seeking Behavior in RatsPharmaceuticals (Basel)January 1, 2025Jessalyn Pla-Tenorio, Bethzaly Velazquez-Perez, Yainira Mendez-Borrero, Myrella L. Cruz, Marian T. Sepulveda-Orengo, Richard J. Noelcat#644701, Biolegend), EAAT2/GLT-1 (dil. 1/400, cat#AB1783, Millipore), and SCL711A/xCT (1/200 dil., cat# PA1-16893, Invitrogen), respectively. A tissue section was used as a negative control receiving PBS instead of

(16) xCT as a potential marker for neuroendocrine cells in high-risk prostate cancer and the relation to AL122023.1-miR-26a/30d/30e axisPloS oneJanuary 1, 2025Wilhelm ED, Dankert JT, Wiesehöfer M, Wach S, Wagner M, Spahn M, Kruithof-de Julio M, Wennemuth G.double-checked by a commercial vendor (LGC Genomics, Berlin, Germany). Using three different antibodies (PA1-16893, Invitrogen; #711589 (clone 3HCLC), Invitrogen; 12691S (clone D2M7A), Cell Signaling), xCT was uniquely

(17) Integrated multi-omics analysis identifies features that predict human pluripotent stem cell-derived progenitor differentiation to cardiomyocytesJournal of Molecular and Cellular CardiologyNovember 1, 2024Aaron D. Simmons, Claudia Baumann, Xiangyu Zhang, Timothy J. Kamp, Rabindranath De La Fuente, Sean P. Palecek39.4D5-S,msIgG2b,1:20 PDGFRA,BD 556002,msIgG2a (PE),20uL KDR,BD 560495,msIgGl (AF647),20uL SLC7A11,Thermo PA1-16893,rbIgG,1:100 RHOBTB3,Sigma SAB4500898,rbIgG,1:100 DGKI,sc-166439,msIgG1,1:100 TRIM55,sc-517149,msIgGl,1:200

(18) p38 MAPK inhibitor SB202190 suppresses ferroptosis in the glutamate-induced retinal excitotoxicity glaucoma modelNeural regeneration researchOctober 1, 2024Feng L, Wang C, Zhang C, Zhang W, Zhu W, He Y, Xia Z, Song W.Cat# ab125066, RRID: AB_10973901); and SLC7A11 polyclonal antibody (1:1000, Thermo Fisher Scientific, PA1-16893). The membranes were washed and incubated with the goat anti-rabbit IgG H&L (HRP; Zen Bio, Chengdu,

(19) HECTD2 as a target for veratric acid in the regulation of ferroptosis in renal cell carcinomaAmino acidsSeptember 30, 2024Lv D, Xiang Y, Song T, Li J, Chen Y, Huili Y, Shen T.(bs-20375R, BIOSS, China), rabbit anti-GPX4 (MA5-32,827, Invitrogen, USA), or rabbit anti-SLC7A11 (PA1-16893, Invitrogen, USA). After that, they were treated with goat anti-rabbit IgG (31460, Invitrogen, USA)

(20) 8-weeks aerobic exercise ameliorates cognitive deficit and mitigates ferroptosis triggered by iron overload in the prefrontal cortex of APP Swe/PSEN 1dE9 mice through Xc-/GPx4 pathwayFrontiers in NeuroscienceSeptember 9, 2024Chaoyang Li, Kaiyin Cui, Xinyuan Zhu, Shufan Wang, Qing Yang, Guoliang FangGPx4 (Beyotime, AF7020, 1:1000), β-actin (Beyotime, AA128, 1:1000), and Xc− (Thermo Fisher Scientific, PA1-16893, 1:1000). The next day, wash the membrane 3 times with TBST for 5 min each to remove residual primary

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SLC7A11 Antibody

SLC7A11 Antibody from Thermo Fisher Scientific

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SLC7A11 Antibody from Thermo Fisher Scientific

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