pADPr (10H) Antibody sc-56198 from Santa Cruz Biotechnology, Inc.

Product Specs
ItempADPr (10H) Antibody
CompanySanta Cruz Biotechnology, Inc.
Price $316.00Supplier Page View Company Product Page
Catalog Numbersc-56198
Antibody TypePrimary Antibodies
Clone10H
Quantity100 µg/ml
ReactivityNSR
ApplicationsWB, IF, ELISA
Conjugate/TagUnconjugated
Hostmouse
ClonalityMonoclonal
FormatPurified
IsotypeIgG3
TargetpADPr

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Santa Cruz Biotechnology, Inc.

10410 Finnell Street

Dallas, Texas 75220

United States

Phone: 1-800-457-3801
831-457-3801

Company Profile

Website: http://www.scbt.com/

(1) Delaying Stress Granule Disassembly by PARG Inhibition Attenuates Renal Tubular Cell Pyroptosis in Acute Kidney InjuryInt J Mol SciAugust 12, 2026Yiyun Song, Shan Jiang, Min Yang, Jinchai Zhu, Banghuan Hu, Hua Su(1:1000, A5637, ABclonal, China). PARylation levels were detected using an anti-PAR antibody (1:100, sc-56198, Santa Cruz, Santa Cruz, CA, USA) and a goat anti-rabbit IgG (H+L) cross-adsorbed secondary antibody

(2) Lactylome Reprogramming Mediates Therapeutic Response and Adaptation to Neoadjuvant Chemotherapy in Esophageal Squamous Cell CarcinomaMolecular & Cellular ProteomicsApril 1, 2026Panpan Peng, Xinyi Cen, Tianxiao Wang, Shuang Wei, Xinbo Wang, Xuelian Ren, Cong Yan, Yongjun Zhu, Qian Niu, Lu Chen, et al.and anti-sirtuin 2 (SIRT2) (19655-1-AP) antibodies were generated by Proteintech Group. Anti-pADPr (sc-56198) antibody was obtained from Santa Cruz Biotechnology. Anti-H2AX (7631) antibody was purchased from Cell Signaling Technology

(3) CRISPR/Cas9 generated DSB clusters mimic complex lesions induced by high-LET radiation and shift repair from c-NHEJ to mutagenic repair pathwaysSci RepOctober 20, 2025Emil Mladenov, Mathias Kallies, Martin Stuschke, Eleni Gkika, George IliakisGeneTex, GTX628789), and mouse-monoclonal, anti-PAR (pADPr Antibody (10 H), Santa Cruz Biotechnology, sc-56198) - all diluted to the company recommended dilutions in PBG. Coverslips were washed three times with

(4) Autophagy-dependent sensitization effects of PARP inhibitors on recurrent nasopharyngeal carcinoma treated with carbon ion and photon irradiationActa Biochimica et Biophysica SinicaSeptember 2, 2025Ziyu Le, Haojiong Zhang, Li Chen, Wanzun Lin, Qingting Huang, Shikai Geng, Wei Hu, Huaiyuan Chen, Fangzhu Wan, Xingyu Liu, et al.1:1000), anti-mouse IgG HRP (7076; 1:1000) and anti-rabbit IgG HRP (7074; 1:1000). pADPr antibody (sc-56198) was purchased from Santa Cruz Biotechnology (Dallas, USA), and its dilution ratio for western blot

(5) PARG Mutation Uncovers Critical Structural Determinant for Poly(ADP-Ribose) Hydrolysis and Chromatin Regulation in Embryonic Stem CellsCellsJuly 9, 2025Yaroslava Karpova, Sara Piatz, Guillaume Bordet, Alexei V. Tulin(Rockland) for 1 h and stained overnight at 4 °C with primary antibodies against pADPr H10 (1:1000, sc-56198, Santa Cruz), β-actin (1:5000, A2228, Millipore Sigma), H3 (1:3000, ab1791, Abcam, Cambridge, MA, USA),

(6) A CRISPR-Cas9 screen reveals genetic determinants of the cellular response to decitabineEMBO ReportsFebruary 10, 2025Pinqi Zhang, Zhuqiang Zhang, Yiyi Wang, Wenlong Du, Xingrui Song, Weiyi Lai, Hailin Wang, Bing Zhu, Jun Xiong,Thermo Scientific,PA5-51862 RCOR1,Sigma,07-455 RCOR2,ABcam,ab37113 HDAC1,Proteintech,6085-1-Ig ACTB,ABclonal,AC026 GFP,ABclonal,AE011 GFP,ABcam,ab13970 GFP,MBL,598 H3,ABclonal,A2348 FLAG,Sigma,B3111 PARylation,Santa Cruz,sc-56198 XRCC1,ABclonal,A0442 Alexa Fluor Plus 555-conjugated goat anti-mouse IgG (H + L),Thermo Scientific,A32727 Alexa

(7) An NAD+ with dually modified adenine for labeling ADP-ribosylation-specific proteinsTetrahedronDecember 1, 2024Lei Zhang, Xiao-Nan Zhang, Arshad J. Ansari, Yong Zhangng), Fc-Macro (200 ng, EMD Millipore, MABE1016), and 10H antibody (100 ng, Santa Cruz Biotechnology, sc-56198), in PCR tubes and incubated at 25°C for 10 min. Following 10-min UV irradiation at 365 nm, samples

(8) Adaptive genetic mechanisms in mammalian Parp1 locusG3: Genes, Genomes, GeneticsSeptember 4, 2024Yaroslava Karpova, Alexei V Tulinnonfat milk (Rockland) and stained overnight at 4°C with primary antibodies against pADPr (1:1000, sc-56198, Santa Cruz), β-actin (1:5000, A2228, Millipore Sigma), β-tubulin (1:20.000, B512, Sigma), PARP1 (1:1000,

(9) 1,25-Dihydroxyvitamin D3 Suppresses UV-Induced Poly(ADP-Ribose) Levels in Primary Human Keratinocytes, as Detected by a Novel Whole-Cell ELISAInternational Journal of Molecular SciencesMay 21, 2024Warusavithana Gunawardena Manori De Silva, Vanessa Bernadette Sequeira, Chen Yang, Katie Marie Dixon, Andrew J. A. Holland, Rebecca Sara Mason, Mark Stephen Rybchynin PBS, pH 7.4, and pADPr was detected by incubation of mouse monoclonal IgG3 pADPr Antibody (10H): sc-56198 antibody (Santa Cruz Biotechnologies, Dallas, TX, USA) at 5 µg/mL in HDC overnight at 4 °C. Isotype

(10) Mono-methylated histones control PARP-1 in chromatin and transcriptioneLifeMay 1, 2024Gbolahan Bamgbose, Guillaume Bordet, Niraj Lodhi, Alexei TulinAbcam, ab9051), anti-H4 (Mouse, 1:1000, Abcam, ab31830), anti-pADPr (Mouse monoclonal, 1:500, 10 H - sc-56198, Santa Cruz), anti-H3 (Rabbit polyclonal, 1/1000, FL-136 sc-10809 Santa Cruz). Gene ontology (GO) Gene

(11) Mono-methylated histones control PARP-1 in chromatin and transcriptionElifeMay 1, 2024Gbolahan Bamgbose, Guillaume Bordet, Niraj Lodhi, Alexei TulinAbcam, ab9051), anti-H4 (Mouse, 1:1000, Abcam, ab31830), anti-pADPr (Mouse monoclonal, 1:500, 10 H - sc-56198, Santa Cruz), anti-H3 (Rabbit polyclonal, 1/1000, FL-136 sc-10809 Santa Cruz). Gene ontology (GO) Gene

(12) A synergistic two-drug therapy specifically targets a DNA repair dysregulation that occurs in p53-deficient colorectal and pancreatic cancersCell reports. MedicineMarch 19, 2024Alruwaili MM, Zonneville J, Naranjo MN, Serio H, Melendy T, Straubinger RM, Gillard B, Foster BA, Rajan P, Attwood K, et al.RRID:AB_331464 "anti-PAR (mouse monoclonal anti-PADPr, Clone 10h)",Santa Cruz Biotechnology,"Cat# sc-56198, RRID:AB_785249" "anti-PARP1 (mouse monoclonal antibody, Clone 5a5)",Santa Cruz Biotechnology,Cat#

(13) Augmented Concentration of Isopentyl-Deoxynyboquinone in Tumors Selectively Kills NAD(P)H Quinone Oxidoreductase 1-Positive Cancer Cells through Programmed Necrotic and Apoptotic MechanismsCancers (Basel)December 14, 2023Jiangwei Wang, Xiaolin Su, Lingxiang Jiang, Matthew W. Boudreau, Lindsay E. Chatkewitz, Jessica A. Kilgore, Kashif Rafiq Zahid, Noelle S. Williams, Yaomin Chen, Shaohui Liu, et al.immunofluorescence included here: antibodies against NQO1 (1:200, sc-32793), β-actin (1:1000, sc-47778), PAR (1:200, sc-56198), α-tubulin (1:1000) and P53 (1:200, DO-1). These were obtained from Santa Cruz Biotechnology (Dallas,

(14) Disrupting Poly(ADP-ribosyl)ating Pathway Creates Premalignant Conditions in Mammalian LiverInt J Mol SciDecember 6, 2023Yaroslava Karpova, David J. Orlicky, Edward E. Schmidt, Alexei V. Tulinseparated in 14% PAAG gel and transferred to nitrocellulose membrane. Antibodies used were against pADPr (sc-56198, Santa Cruz, Dallas, TX, USA), H3 (sc-10809, Santa Cruz, Dallas, TX, USA), anti-mouse HRP (G21040, Invitrogen,

(15) Synthesis and Degradation of Poly(ADP-ribose) in Zebrafish Brain Exposed to AluminumInternational journal of molecular sciencesMay 15, 2023Bianchi AR, La Pietra A, Guerretti V, De Maio A, Capriello T, Ferrandino I.anti-PARP1 N20 (sc-1561, Santa Cruz, Biotechnology, Inc., 1:1000), monoclonal anti-poly ADP-ribose (PAR) (sc-56198, Santa Cruz, Biotechnology, Inc., 1:500), and monoclonal anti-β-actin (sc-517582, Santa Cruz Biotechnology, Inc

(16) Synthesis of Bispecific Antibody Conjugates Using Functionalized Poly-ADP-ribose PolymersBiochemistryMarch 21, 2023Cheng Q, Zhang XN, Li J, Chen J, Wang Y, Zhang Y.

(17) Thioparib inhibits homologous recombination repair, activates the type I IFN response, and overcomes olaparib resistanceEMBO molecular medicineMarch 8, 2023Wang LM, Wang P, Chen XM, Yang H, Song SS, Song Z, Jia L, Chen HD, Bao XB, Guo N, et al.(sc‐581), MSH2 (sc‐494), TNKS1/2 (sc‐365897), p‐JNK (sc‐6254), PARP1 (sc‐7150) and PAR [pADPr (10H) (sc‐56198)] were from Santa Cruz Biotechnology (Santa Cruz, CA). Antibody against p‐RPA32 (PLA0071) was from Sigma

(18) Attenuation of Tumor Burden in Response to Rucaparib in Lung Adenocarcinoma: The Contribution of Oxidative Stress, Apoptosis, and DNA DamageInternational journal of molecular sciencesJanuary 30, 2023Pérez-Peiró M, Valentí-Serra P, León-González B, Ampurdanés C, Duran X, Yélamos J, Barreiro E.Antibody,Dilution,Catalog Number,Supplier Anti-pADPr antibody,1:500,sc-56198,"Santa Cruz Biotechnology, Dallas, TX, USA" Anti-PARP-1 antibody,1:20,-,In-house generated affinity

(19) A Poly-ADP-Ribose Polymer-GCSF ConjugateBiomacromoleculesDecember 12, 2022Cheng Q, Zhang XN, Zhang L, Chen J, Wang Y, Zhang Y.

(20) Poly ADP-ribosylation of SET8 leads to aberrant H4K20 methylation in mammalian nuclear genomeCommunications biologyNovember 25, 2022Estève PO, Sen S, Vishnu US, Ruse C, Chin HG, Pradhan S.(Cell Signaling Technology # 83732S) or polyADP-ribose (monoclonal 10H, Santa Cruz Biotechnology # sc-56198) antibodies. For mass spectrometry analyses, 500 nM of PARP1 recombinant enzyme was incubated with 160

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pADPr (10H) Antibody

pADPr (10H) Antibody from Santa Cruz Biotechnology, Inc.

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Santa Cruz Biotechnology, Inc.

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pADPr (10H) Antibody from Santa Cruz Biotechnology, Inc.

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