O-GlcNAc (CTD110.6) Antibody sc-59623 from Santa Cruz Biotechnology, Inc.

Product Specs
ItemO-GlcNAc (CTD110.6) Antibody
CompanySanta Cruz Biotechnology, Inc.
Price $316.00Supplier Page View Company Product Page
Catalog Numbersc-59623
Antibody TypePrimary Antibodies
CloneCTD110.6
Quantity200 µg/ml
Reactivitybroad species
ApplicationsWB, IP
FormatPurified
Hostmouse
Conjugate/TagUnconjugated
ClonalityMonoclonal
IsotypeIgM
TargetO-GlcNAc

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Santa Cruz Biotechnology, Inc.

10410 Finnell Street

Dallas, Texas 75220

United States

Phone: 1-800-457-3801
831-457-3801

Company Profile

Website: http://www.scbt.com/

(1) Everolimus destabilizes thymidylate synthase via suppressing its O-GlcNAcylation and sensitizes HER2-negative breast cancer to fluorouracilCell Death & DiseaseApril 4, 2026Xiao-Ting Jiang, Huipei Gan, Shaoyi Wang, Linghan Wang, Zijie Cai, Lok Lam Wong, Jingru Wang, Mengdi Zhu, Nianqiu Liu, Wang Yang, et al.Thymidine Kinase 1 Rabbit mAb,Abclonal,A13612 DPYD Rabbit pAb,Proteintech,27662-1-AP Anti-mouse O-GlcNAc Antibody,Santa Cruz,sc-59623 MGEA5 Rabbit pAb,Proteintech,14711-1-AP OGT Rabbit mAb,Abclonal,A3501 HRP-conjugated GAPDH Mouse

(2) O-GlcNAcylation regulates microglial neuroinflammation in Parkinson’s diseasenpj Parkinson's DiseaseMarch 28, 2026Dong Yeol Kim, Sang-Min Kim, Chanhaeng Lee, Inn-Oc Hanincubated overnight at 4 °C with primary antibodies (1:1000) against various targets, including O-GlcNAc (sc-59623, RL2, Santa Cruz, Dallas, TX, USA), OGT (sc-74546, Santa Cruz), OGA (14771-1-AP, Proteintech, Rosemont,

(3) Enhancing protein O-GlcNAcylation in down syndrome mice mitigates memory dysfunctions through the rescue of mitochondrial bioenergetics, stress responses and pathological markersRedox biologySeptember 1, 2025Lanzillotta C, Prestia F, Greco V, Iavarone F, Cordella F, Sette C, Forte E, Tramutola A, Lanzillotta S, Cassano T, et al.incubated overnight at 4 °C with the following primary antibodies: anti-O-GlcNAc CTD110.6 (1:100; mouse, SC-59623, Santa Cruz Biotechnology), anti-O-GlcNAc RL2 (1:50; mouse, MABS157, Sigma-Aldrich), anti-Tau S202/Y205

(4) Evidence for functional regulation of the KLHL3/WNK pathway by O-GlcNAcylationGlycobiologyAugust 11, 2025Jimin Hu, Duc T. Huynh, Denise E. Dunn, Jianli Wu, Cindy Manriquez-Rodriguez, Qianyi E. Zhang, Gabrielle A. Hirschkorn, Tetsuya Hirata, George R. Georgiou, Samuel A. Myers, et al.sc-59624 (discontinued)","1:1000 (WB), 1:400 (IF)" O-GlcNAc (CTD110.6),"Santa Cruz Biotechnology, sc-59623",1:200 phospho-WNK4 (Ser575),"ThermoFisher, PA5–114673",1:1000 V5,"Cell Signaling Technology, 13202

(5) O-GlcNAcylation-dependent liquid-liquid phase separation regulates the nuclear translocation of YAP to exacerbate vascular neointimal hyperplasiaTheranosticsJuly 11, 2025Ping Weng, Yilin Wen, Zhiyi Yuan, Limei Ma, Liming Yang, Chengju Li, Wanping Zhang, Chao YuOPN (proteintech, 22952-1-AP, 1:1000), STAT3 (Cell Signaling, #9139, 1:1000), O-GlcNAc (Santa Cruz, sc-59623, 1:1000). Quantitative Real-Time PCR (qRT-PCR): Relative quantitative RT-PCR (qPCR) was carried out

(6) Dynamic regulation of the COPII interactome and collagen trafficking by site-specific glycosylation of Sec24DbioRxivJune 17, 2025Tetsuya Hirata, Dharmendra Choudhary, Brittany J. Bisnett, Erik J. Soderblom, Ela W. Knapik, Michael Boycefrom Abcam; Mouse anti-Calnexin (2A2C6, #66903–1-Ig) from Proteintech; mouse anti-O-GlcNAc (CTD110.6, #sc-59623), and mouse anti-ERGIC53 (C-6, #sc-365158) from Santa Cruz Biotechnology; anti-procollagen I (PIP, #42024)

(7) Evidence for Functional Regulation of the KLHL3/WNK Pathway by O-GlcNAcylationbioRxivMarch 1, 2025Jimin Hu, Duc T. Huynh, Denise E. Dunn, Jijanli We, Cindy Manriquez-Rodriguez, Qianyi E. Zhang, Gabrielle A. Hirschkorn, George R. Georgiou, Tetsuya Hirata, Samuel A. Myers, et al.sc-59624 (discontinued)","1:1000 (WB), 1:400 (IF)" O-GlcNAc (CTD110.6),"Santa Cruz Biotechnology, sc-59623",1:200 phospho-WNK4 (Ser575),"ThermoFisher, PA5-114673",1:1000 V5,"Cell Signaling Technology, 13202

(8) Pharmacological Dissection Identifies Retatrutide Overcomes the Therapeutic Barrier of Obese TNBC Treatments through Suppressing the Interplay between Glycosylation and Ubiquitylation of YAPAdvanced ScienceJanuary 27, 2025Xin Cui, Yueming Zhu, Lidan Zeng, Mengyuan Zhang, Amad Uddin, Theresa W. Gillespie, Lauren E. McCullough, Shaying Zhao, Mylin A. Torres, Yong Wan#14074; p‐YAP (S127): CST #4911; EIF3H: Santa Cruz sc‐271283; Ubquitin: CST #43124; O‐GlcNAc: Santa Cruz sc‐59623; OGT: Invitrogen PA5‐22071; STT3A: Proteintech 12034‐1‐AP; MGAT1: Sigma SAB1400165; MAN1C1: Sigma SAB1409548;

(9) KDM2B regulates stroke injury by modulating OGT-mediated 0-GlcNAcylation of SLC7A11Communications BiologyNovember 18, 2024Yi Li, Liangbo Niu, Dai Zheng, Xinxing Zhang, Lu Feng, Jing Fu(Z045801-5, Dako), SLC7A11 (26864‐1‐AP, 1:1000, Proteintech), OGT (ab96718, 1:1000, Abcam), O‐GlcNAcylation (sc‐59623, 1:1000, Santa Cruz), NeuN (ab104224, 1:1000, Abcam), PSD95 (ab18258, 1:1000, Abcam), CD206 (ab64693,

(10) The DNA damage-independent ATM signalling maintains CBP/DOT1L axis in MLL rearranged acute myeloid leukaemiaOncogeneJune 14, 2024Guangming Wang, Wenjun Zhang, Jie Ren, Yu Zeng, Xiuyong Dang, Xiaoxue Tian, Wenlei Yu, Zheng Li, Yuting Ma, Pingping Yang, et al.gift from Weiguo Zhu lab, Shenzhen University, WB, 1:1000), Mouse Anti-O-GlcNAcylation (Santa Cruz, #sc-59623, WB 1:1000), Rabbit Anti-CBP (Cell Signalling Technology, #7389, WB 1:1000, IP 1:100), Mouse Anti-CBP

(11) Protective effect of increased O-GlcNAc cycling against 6-OHDA induced Parkinson’s disease pathologyCell Death & DiseaseApril 23, 2024Dong Yeol Kim, Sang-Min Kim, Eun-Jeong Cho, Hyo-Bum Kwak, Inn-Oc Hananti-OGA (1:100, 14711-1-AP, Proteintech), anti-OGT (1:100, sc-74546, Santa Cruz), anti-O-GlcNAc (1:100, sc-59623, Santa Cruz), anti-GFAP (1:100, G3893, Sigma-Aldrich), anti-Iba 1 (1:100, ab178864, Abcam), and anti-iNOS

(12) Zbtb16 increases susceptibility of atrial fibrillation in type 2 diabetic mice via Txnip-Trx2 signalingCellular and molecular life sciences : CMLSFebruary 13, 2024Wei ZX, Cai XX, Fei YD, Wang Q, Hu XL, Li C, Hou JW, Yang YL, Chen TZ, Xu XL, et al.phospho-CaMKIIδ (1:1000; ab182647; Abcam), oxidized CaMKII (1:1000; GTX36254; GeneTex, USA), O-GlcNAc (1:1000; sc-59623; Santa Cruz, USA), Txnip (1:1000; 14715S; Cell Signaling Technology, Danvers, MA), Trx2 antibody (1:1000;

(13) T‐2 Toxin‐Mediated β‐Arrestin‐1 O‐GlcNAcylation Exacerbates Glomerular Podocyte Injury via Regulating Histone AcetylationAdvanced ScienceFebruary 1, 2024Tushuai Li, Wenxue Sun, Shenglong Zhu, Chengsheng He, Tong Chang, Jie Zhang, Yongquan Chenanti‐Lamin A (ab8980) were acquired from Abcam Corporation (Cambridge, MA, USA). Mouse anti‐O‐GlcNAc (Sc‐59623) and mouse anti‐β‐actin (Sc‐8432) were acquired from Santa Cruz Biotechnology Co., Ltd (Santa Cruz,

(14) Nutlin-3a induces KRAS mutant/p53 wild type lung cancer specific methuosis-like cell death that is dependent on GFPT2J Exp Clin Cancer ResDecember 14, 2023Dasom Kim, Dongwha Min, Joohee Kim, Min Jung Kim, Yerim Seo, Byung Hwa Jung, Seung-Hae Kwon, Hyunju Ro, Seoee Lee, Jason K. Sa, et al.manufacturer’s instructions. Primary antibodies against p53 (sc-126), B-Raf (sc-5284), c-Myc (sc-40), O-GlcNAc (sc-59623), and β-actin (sc-47778) were purchased from Santa Cruz Biotechnology (CA, USA). Antibody against KRAS

(15) Targeting USP8 Inhibits O‐GlcNAcylation of SLC7A11 to Promote Ferroptosis of Hepatocellular Carcinoma via Stabilization of OGTAdvanced ScienceNovember 1, 2023Jianing Tang, Guo Long, Kuan Hu, Desheng Xiao, Shuang Liu, Liang Xiao, Ledu Zhou, Yongguang Tao26864‐1‐AP), OGT (Proteintech, 11576‐2‐AP), USP8 (Proteintech, 67321‐1‐Ig), O‐GlcNAcylation (Santa Cruz, sc‐59623) GAPDH (Proteintech, 60004‐1‐Ig), Flag (Proteintech, 66008‐4‐Ig), Myc (Proteintech, 60003‐2‐Ig), HA

(16) Critical Role of Novel O-GlcNAcylation of S550 and S551 on the p65 Subunit of NF-κB in Pancreatic CancerCancersSeptember 27, 2023Motolani A, Martin M, Wang B, Jiang G, Alipourgivi F, Huang X, Safa A, Liu Y, Lu T.USA), anti-FLAG (Sigma-Aldrich, F1804, St. Louis, MI, USA), anti-O-GlcNAc (Santa Cruz Biotechnology, sc-59623, Dallas, TX, USA), anti-IκBα (Cell signaling technology, 9242s, Dallas, TX, USA), anti-pS536 (Cell signaling,

(17) Antioxidant activity of glucosamine and its effects on ROS production, Nrf2, and O-GlcNAc expression in HMEC-1 cellsCurrent Research in ToxicologySeptember 22, 2023B. Fernández-Rojas, T. Gómez-Sierra, O.N. Medina-Campos, J. Hernández-Juárez, P.A. Hernández-Cruz, I.B. Gallegos-Velasco, Y. Pérez-Cervera, J. Pedraza-Chaverri4′,6-diamidino-2-phenylindole dihydrochloride (DAPI, from Invitrogen, CA, USA), Nrf2 (SC-722) and O-GlcNAc (SC-59623) antibodies were from Santa Cruz Biotechnology (Dallas, TX, USA). Ethylenediaminetetraacetic acid disodium

(18) The deubiquitinase EIF3H promotes hepatocellular carcinoma progression by stabilizing OGT and inhibiting ferroptosisCell communication and signaling : CCSAugust 9, 2023Tang J, Long G, Li X, Zhou L, Zhou Y, Wu Z.antibodies were EIF3H (Proteintech, 11,310–1-AP), OGT (Proteintech, 66,823–1-Ig), O-GlcNAc (Santa cruz, sc-59623), Myc (Proteintech, 60,003–2-Ig), HA (Proteintech, 51,064–2-AP), and GAPDH (Proteintech, 60,004–1-Ig).

(19) Glucose enrichment impair neurotransmission and induce Aβ oligomerization that cannot be reversed by manipulating O-β-GlcNAcylation in the C. elegans model of Alzheimer''s diseaseThe Journal of nutritional biochemistryOctober 1, 2022Ahmad W.

(20) GFAT1-linked TAB1 glutamylation sustains p38 MAPK activation and promotes lung cancer cell survival under glucose starvationCell discoveryAugust 9, 2022Wei S, Zhao Q, Zheng K, Liu P, Sha N, Li Y, Ma C, Li J, Zhuo L, Liu G, et al.(ab8227, 1:1000) were purchased from Abcam. Antibodies that recognize p62 (sc-28359, 1:1000), O-GlcNAc (sc-59623, 1:1000) LC3B (sc-271625, 1:1000) and p-p38 (sc-7973, 1:1000) were obtained from Santa Cruz. Antibody

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O-GlcNAc (CTD110.6) Antibody

O-GlcNAc (CTD110.6) Antibody from Santa Cruz Biotechnology, Inc.

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Santa Cruz Biotechnology, Inc.

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O-GlcNAc (CTD110.6) Antibody from Santa Cruz Biotechnology, Inc.

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