Anti-Cdk6 antibody ab151247 from Abcam

Product Specs
ItemAnti-Cdk6 antibody
CompanyAbcam
Price Supplier Page View Company Product Page
Catalog Numberab151247
Quantity100 µL
ApplicationsICC/IF, IHC-P, WB
Conjugate/TagUnconjugated
ClonalityPolyclonal
IsotypeIgG
HostRabbit
NCBI Gene AliasesMCPH12, PLSTIRE
Concentration0.9 mg/ml
Research AreaOncology
Gene NameCDK6
ReactivityHuman, Mouse, Rat
Antibody TypePrimary Antibody
TargetCDK6
NCBI Full Gene Namecyclin dependent kinase 6

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Abcam

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Cambridge CB2 0AX

United Kingdom

Phone: +44 (0) 1223 696000 (option 1)
+44 (0) 1223 696000 (option 2)
+44 (0) 1223 771600

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Website: http://www.abcam.com

(1) Proteasome activity maintains cell-type-specific gene expressionCell ReportsFebruary 24, 2026Xiuxiu Lu, Vasty Osei-Amponsa, Germán Michelis, Rithik E. Castelino, Hitendra Negi, Sudipto Das, Jesse L. Turner, Julianna C. King, Daniel Martin, Yan Wang, et al.anti-Rpn8 (ab140428, Abcam), anti-Rpt3 (ab140515, Abcam), anti-K48 ubiquitin (ab140601, Abcam), anti-CDK6 (Ab151247, Abcam), anti-SEC31A (ab86600, Abcam), anti-ubiquitin (3936, Cell Signaling Technology (CST)), anti-Rpn1

(2) A Machine-Learning Prognostic Model for Colorectal Cancer Using a Complement-Related Risk SignatureOncology ResearchOctober 22, 2025Jun Li, Kangmin Yu, Zhiyong Chen, Dan Xing, Binshan Zha, Wentao Xie, Huan Ouyang, Changjun YuUK), N-cadherin (Abcam, ab76011), E-cadherin (Abcam, ab40772), c-Myc (Abcam, ab32072), CDK6 (Abcam, ab151247), Bax (Abcam, ab216985), and Bcl-2 (Abcam, ab194583). The next day, blots were washed three times in

(3) A Machine-Learning Prognostic Model for Colorectal Cancer Using a Complement-Related Risk SignatureOncology ResearchOctober 22, 2025Jun Li, Kangmin Yu, Zhiyong Chen, Dan Xing, Binshan Zha, Wentao Xie, Huan Ouyang, Changjun YuUK), N-cadherin (Abcam, ab76011), E-cadherin (Abcam, ab40772), c-Myc (Abcam, ab32072), CDK6 (Abcam, ab151247), Bax (Abcam, ab216985), and Bcl-2 (Abcam, ab194583). The next day, blots were washed three times in

(4) Raddeanin A exerts potent efficacy against non-small cell lung cancer by inhibiting cyclin-dependent kinase 6Transl OncolApril 11, 2025Xian Wang, Xiao Lin, Yuxin Liu, Chunbo Ma, Mengchu Liu, Jiayu Bai, Yihan Ye, Chengguang Zhao, Lehe Yang, Xiaoying Huang, et al.Cell Signaling Technology, 1:1000), anti-CDK4 (ab199728, Abcam, 1:1000), anti-Rb (ab226979, Abcam, 1:1000), anti-CDK6 (ab151247, Abcam, 1:1000), anti-CyclinD1 (ab226977, Abcam, 1:1000), anti-Rb (phospho S807) (ab184796, Abcam, 1:1000),

(5) Lncrna FGFR3-AS1 Is a Prognostic Indicator for Ovarian Cancer and Induces Cell Proliferation and Hinders ApoptosisIranian Journal of Public HealthNovember 12, 2023Yuyang Zhang, Lili Sun, Tieshuang Chen, Yuanyuan Yue, Lin Zhao, Dan Zhangblocking liquid for 1 h. CCND1 antibody (1:3000, Cat. #ab134175, Abcam), CDK6 antibody (1:1000, Cat. #ab151247, Abcam), MAPK9 antibody (1:3000, Cat. #ab76125, Abcam), PIK3CA antibody (1:1000, Cat. #ab40776, Abcam),

(6) Celastrol-regulated gut microbiota and bile acid metabolism alleviate hepatocellular carcinoma proliferation by regulating the interaction between FXR and RXRα in vivo and in vitroFrontiers in PharmacologyFebruary 15, 2023Dequan Zeng, Lipen Zhang, Qiang LuoStates","55,506" Anti-CDK4,"CST, Boston, United States","3,136" Anti-CDK6,"Abcam, Cambridge, UK",AB151247 Anti-cdc25A,"Abcam, Cambridge, UK",Ab79252 Anti-p21,"Abcam, Cambridge, UK",Ab109520 Anti-ki67,"Abcam,

(7) XTP1 facilitates the growth and development of gastric cancer by activating CDK6Annals of Translational MedicineJanuary 31, 2023Kang Li, Rulan Ma, Lei Meng, Qing Wang, Jun Cao, Dawei Yuan, Tuanhe Sun, Li Kang, Nan Hao, Haonan Wang, et al.differentiation (CD)44 (Abcam, USA, ab157107, 1:2000), anti-cyclin-dependent kinase 6 (CDK6) (Abcam, USA, ab151247, 1:1,000), anti-ras homolog family member U (RHOU) (Abcam, USA, ab80315, 1:1,000), and anti-rabbit IgG

(8) Hsa_circ_0005050 regulated the progression of oral squamous cell carcinoma via miR-487a-3p/CHSY1 axisJournal of Dental SciencesJanuary 1, 2023Xubin Chen, Qiaojiang Chen, Chen Zhao, Zhiqi Luincubated overnight with primary antibodies: PCNA (ab18197, 1:1000, Abcam, Cambridge, MA, USA), CDK6 (ab151247, 1:1000, Abcam), Bcl2 (ab32124, 1:1000, Abcam), Bax (ab182733, 1:1000, Abcam), CHSY1 (ab153813, 1:1000,

(9) Alpha Protein Kinase 2 Promotes Esophageal Cancer via Integrin Alpha 11BioMed Research InternationalJune 29, 2022Julaiti Ainiwaer, Liwei Zhang, Maidiniyeti Niyazi, Edris Awut, Shutao Zheng, Ilyar Sheyhidin, JiangHong Dai(1 : 3000, CST, #2972), P-mTOR (1 : 1000, Beijing Solebold Antibody, #K006205P), CDK6 (1 : 1000, Abcam, #ab151247), and PIK3CA (1 : 1000, Abcam, #ab40776). Goat Anti-Rabbit (1 : 3000, Beyotime, #A0208) was the secondary

(10) Identification of NLE1/CDK1 axis as key regulator in the development and progression of non-small cell lung cancerFrontiers in oncologyJanuary 1, 2022Xu P, Wang L, Mo B, Xie X, Hu R, Jiang L, Hu F, Ding F, Xiao H.(1:500, #4370, CST); mTOR (1:2000, #ab2732, Abcam); P-mTOR (1:1000, #ab2732, Abcam); CDK6 (1:1000, #ab151247, Abcam); PIK3CA (1:1000, #ab40776, Abcam); AKT (1:2000, #10176-2-AP, Proteintech); p-AKT (1:1000, #10176-2-AP,

(11) CircMYH9 drives colorectal cancer growth by regulating serine metabolism and redox homeostasis in a p53-dependent mannerMolecular cancerSeptember 8, 2021Liu X, Liu Y, Liu Z, Lin C, Meng F, Xu L, Zhang X, Zhang C, Zhang P, Gong S, et al.antibodies were used: anti-CDK1 (abcam, 2546 ab133327), anti-cyclin D1 (CST, 2922), anti-CDK6 (Abcam, ab151247), anti-cyclin E2 (CST, 4132), anti-PHGDH (Proteintech, 14,719–1-AP), anti-PSPH (Proteintech, 14,513–1-AP),

(12) HSPA4 Knockdown Retarded Progression and Development of Colorectal CancerCancer Manag ResJune 14, 2021Mingliang Zhang, Weigang Dai, Zhanyu Li, Liang Tang, Jianhui Chen, Chuangqi Chen(1:1000, CST, #4685), p-Akt (1:1000, Bioss, #BS-5193R), CCND1 (1:2000, CST, #2978), CDK6 (1:1000, Abcam, #ab151247), PIK3CA (1:1000, Abcam, #ab40776) and GAPDH (1:3000, Bioworld, #AP0063). The blots were visualized

(13) HSPA4 Knockdown Retarded Progression and Development of Colorectal CancerCancer Management and ResearchJune 14, 2021Mingliang Zhang, Weigang Dai, Zhanyu Li, Liang Tang, Jianhui Chen, Chuangqi Chen(1:1000, CST, #4685), p-Akt (1:1000, Bioss, #BS-5193R), CCND1 (1:2000, CST, #2978), CDK6 (1:1000, Abcam, #ab151247), PIK3CA (1:1000, Abcam, #ab40776) and GAPDH (1:3000, Bioworld, #AP0063). The blots were visualized

(14) Eukaryotic Translation Initiation Factor 3 Subunit B Is a Promoter in the Development and Progression of Pancreatic CancerFrontiers in OncologyApril 29, 2021Haoyuan Ren, Gang Mai, Yong Liu, Rongchao Xiang, Chong Yang, Wenjie Su(1:1,000, CST, 4685), p-Akt (1:500, R&D, AF887-sp), CCND1 (1:2,000, Abcam, 2978), CDK6 (1:1,000, Abcam, ab151247), and PIK3CA (1:1,000, Abcam, ab40776). The secondary antibody used in western blotting was goat anti-rabbit

(15) Silencing of PSMC2 inhibits development and metastasis of prostate cancer through regulating proliferation, apoptosis and migrationCancer cell internationalApril 26, 2021Chen Q, Fu L, Hu J, Guo G, Xie A.D1 (Cat #4685/2978, CST, Danvers, MA, USA), p-Akt (Cat #bs-5193r, Bioss, Beijing, China), CDK6 (Cat #ab151247, Abcam, Cambridge, MA, USA), P21 (Cat #BM3990, Boster, Wuhan, China), Ki67 (Cat #ab16667, Abcam, Cambridge,

(16) MicroRNA‑524‑5p regulates the proliferation and invasion of HTR‑8/SVneo trophoblasts by targeting NUMB in the Notch signaling pathwayMolecular Medicine ReportsApril 8, 2021Linmei Zheng, Jie Song, Rong Tang, Xiaoju Chen, Li Wang, Dongcai Wu, Hui Cen, Lei Shiab196495), Notch1 (1:1,000; cat. no. ab52627), cyclin D1 (1:500; cat. no. ab40754), CDK6 (1:2,000; cat. no. ab151247) and GAPDH (1:10,000; cat. no. ab181602) (all Abcam) at 4°C overnight, then incubated with horseradish

(17) MicroRNA-185 inhibits the proliferation and migration of HaCaT keratinocytes by targeting peroxisome proliferator-activated receptor βExperimental and therapeutic medicineApril 1, 2021Yang J, Deng P, Qi Y, Feng X, Wen H, Chen F.with the following primary antibodies: Cyclin D1 (1:200; cat. no. ab16663), CDK6 (1:3,000; cat. no. ab151247), CDK4 (1:1,000; cat. no. ab95255), p-AKT-T308 (1:1,000; cat. no. ab8933), AKT (1:500; cat. no. ab8805)

(18) Silencing LMNB1 Contributes to the Suppression of Lung Adenocarcinoma DevelopmentCancer Management and ResearchMarch 18, 2021Dan Tang, Haihai Luo, An Xie, Zhichun He, Bin Zou, Fei Xu, Wei Zhang, Xinping Xu(CST, Cat. #4685), P-Akt (R&D, Cat. #AF887-sp), CCND1 (cyclin D1, CST, Cat. #2978), CDK6 (Abcam, Cat. #ab151247), PIK3CA (Abcam, Cat. #ab40776) and GAPDH (Bioworld, Cat. #AP0063). Goat anti-rabbit (Beyotime, Cat.

(19) Silencing LMNB1 Contributes to the Suppression of Lung Adenocarcinoma DevelopmentCancer Manag ResMarch 18, 2021Dan Tang, Haihai Luo, An Xie, Zhichun He, Bin Zou, Fei Xu, Wei Zhang, Xinping Xu(CST, Cat. #4685), P-Akt (R&D, Cat. #AF887-sp), CCND1 (cyclin D1, CST, Cat. #2978), CDK6 (Abcam, Cat. #ab151247), PIK3CA (Abcam, Cat. #ab40776) and GAPDH (Bioworld, Cat. #AP0063). Goat anti-rabbit (Beyotime, Cat.

(20) Knockdown of TMED3 inhibits cell viability and migration and increases apoptosis in human chordoma cellsInternational Journal of OncologyMarch 3, 2021Jinxing Yang, Hanwen Huang, Dan Xiao, Yang Duan, Yanfang Zheng, Zhong Chenanti-cyclin D1 (1:2,000; cat. no. 2978; Cell Signaling Technology, Inc.); rabbit anti-CDK6 (1:1,000; cat. no. ab151247; Abcam); and rabbit anti-MAPK9 (1:1,000; cat. no. ab76125; Abcam). The membranes were washed, followed

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Anti-Cdk6 antibody from Abcam

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Anti-Cdk6 antibody from Abcam

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