Fig 1: MRL/LPR mice were injected with the adenovirus containing the shRNA-NC or HE4 shRNA. The protein level of C3, HE4, MMP2, MMP9, p-P65, prss23, and prss35 in renal tissues was determined by the Western blotting assay (n=3, *p<0.05 vs. control, #p<0.05 vs. model, @p<0.05 vs. M+ NC)