Cdc73 Antibody PA5-26189 from Thermo Fisher Scientific

Product Specs
ItemCdc73 Antibody
CompanyThermo Fisher Scientific
Price Supplier Page
Catalog NumberPA5-26189
ApplicationsWB, FCM, ICC, IHC-p
ReactivityHuman (Hu)
Concentration0.5 mg/mL
Antibody TypePrimary
StorageStore at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles
PurityAntigen affinity chromatography, Protein A
Storage Temperature-20° C, Avoid Freeze/Thaw Cycles
ImmunogenKLH conjugated synthetic peptide between 132-161 amino acids from the central region of human CDC73
NCBI Gene AliasesC1orf28, FIHP, HPTJT, HRPT1, HRPT2, HYX
NCBI Full Gene Namecell division cycle 73
HostRabbit
IsotypeIgG
TargetCdc73
ClonalityPolyclonal
FormatPBS with 0.09% sodium azide; pH 7.4
Conjugate/TagUnconjugated
Quantity400 µL

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Thermo Fisher Scientific

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Waltham, MA 02451

United States

Phone: 800-678-5599
Fax: 800-331-2286

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Website: www.thermofisher.com

(1) Inhibition of RNA polymerase II-activating CDK9 and CDK12/13, but not of cell cycle relevant CDKs, induces apoptosis by downregulating the short-lived Bcl-2 proteins Mcl1 and Bfl1/A1Cell Death DisMay 27, 2026Karina S. Krings, Judith Hatzfeld, Sandra Weller, Nadine Borkowski, Tanya R. Llewellyn, Laura Schmitt, Bo Scherer, Harri M. Itkonen, Christoph Peter, Björn Stork, et al.(Cell Signaling, #4223S, 1:1000), anti-Bcl-xL (Cell Signaling, #54H6, 1:1000), anti-CDC73 (Fisher Scientific, PA5-26189, 1:1000), anti-GAPDH (glyceraldehyde 3-phosphate dehydrogenase; Abcam, ab8245, 1:5000), anti-Histon

(2) Stress-mediated aggregation of disease-associated proteins in amyloid bodiesScientific reportsSeptember 2, 2023Chandhok S, Pereira L, Momchilova EA, Marijan D, Zapf R, Lacroix E, Kaur A, Keymanesh S, Krieger C, Audas TE.fluorescence recovery after photobleaching Transfected cells were fixed with methanol (as described above), and probed with anti-CDC73 (Invitrogen, PA5-26189) antibody. Cells were then mounted on glass slides using Fluoromount G (ThermoFisher Scientific). Congo-red

(3) Translocation of cytosolic human Cdc73 to stress granules plays a role in arsenic stress-induced stabilization of p53 mRNAJournal of cell scienceJuly 15, 2023Lee H, Kim TH, Yoo JY.and immunoprecipitation (1:1000). For immunofluorescence microscopy of hCdc73, antibodies from Invitrogen (PA5-26189; 1:100) and Santa Cruz Biotechnology (Dallas, Texas, sc-33638; 1:100) were used. SG marker antibodies

(4) Evolutionary conservation of systemic and reversible amyloid aggregationJournal of cell scienceNovember 15, 2021Lacroix E, Pereira L, Yoo B, Coyle KM, Chandhok S, Zapf R, Marijan D, Morin RD, Vlachos S, Harden N, et al.

(5) Stress-specific aggregation of proteins in the amyloid bodiesFEBS lettersNovember 1, 2019Marijan D, Tse R, Elliott K, Chandhok S, Luo M, Lacroix E, Audas TE.

(6) Local translation in nuclear condensate amyloid bodiesProceedings of the National Academy of Sciences of the United States of AmericaJanuary 1, 0001"Theodoridis PR, Bokros M, Marijan D, Balukoff NC, Wang D, Kirk CC, Budine TD, Goldsmith HD, Wang M, Audas TE, et al."

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Cdc73 Antibody from Thermo Fisher Scientific

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