MMP13 Antibody PA5-27242 from Thermo Fisher Scientific

Product Specs
ItemMMP13 Antibody
CompanyThermo Fisher Scientific
Price Supplier Page
Catalog NumberPA5-27242
Quantity100 µL
ApplicationsImmunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot
Conjugate/TagUnconjugated
FormatPBS with 20% glycerol and 0.025% ProClin 300; pH 7
ReactivityHuman, Mouse, Rat
ClonalityPolyclonal
TargetMMP13
IsotypeIgG
HostRabbit
NCBI Full Gene Namematrix metallopeptidase 13
NCBI Gene AliasesClg, CLG3, MANDP1, MMP-13, MDST, Mmp1
Concentration0.56 mg/mL
ImmunogenCarrier-protein conjugated synthetic peptide encompassing a sequence within the center region of human MMP13. The exact sequence is proprietary
Storage Temperature-20° C, Avoid Freeze/Thaw Cycles
PurityAntigen affinity chromatography
Antibody TypePrimary
StorageStore at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles

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Waltham, MA 02451

United States

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Fax: 800-331-2286

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Website: www.thermofisher.com

(1) Local delivery of OSK factors enables partial cellular reprogramming to mitigate osteoarthritis and cartilage fibrosisExperimental & Molecular MedicineMarch 5, 2026Yi-Wei Liu, Jing-Tao Zou, Jiang-Shan Gong, Ling Jin, Jia Cao, Ze-Hui He, Yu-Xuan Qian, Xin Wang, Mei-Dan Wan, Xin-Yue Hu, et al.against COL2α1 (PA1-26206, Invitrogen), ACAN (GB11373, Servicebio), COLX (ab182563, Abcam), MMP13 (PA5-27242, Invitrogen), P21 (GB11153, Servicebio), DNMT3a (ab188470, Abcam) and the corresponding horseradish

(2) Accelerated cartilage regeneration via chondrocyte metabolic reprogramming using nano-steroid-conjugated mesenchymal stem cells in osteoarthritisTheranosticsJanuary 1, 2026Jong Yeong Lee, Jun Young Park, In Ah Kwon, Su Hyun Lim, Ki Bum Kim, Jun-Young Park, Youn Joo Kang, Sang-Hyun Kim, Dongwoo Khang, Jin Kyeong Choi(1:500, #PA5-119639; Invitrogen), anti-MMP-9 (1:2000, #PA5-13199; Invitrogen), anti-MMP-13 (1:1000, #PA5-27242; Invitrogen), and anti-β-actin (1:1000, #4970; Cell Signaling). Goat anti-rabbit IgG (polyclonal, 1:10000;

(3) Neuropeptide Y1 receptor antagonist alleviated osteoarthritis by restoring chondrocyte autophagy through PI3K/AKT/mTOR signaling pathwayJournal of Orthopaedic TranslationNovember 1, 2025Song Liu, Jianqun Wu, Yucong Lin, Haifeng Liang, Yu Cai, Le Wang, Zhao Wang, Hongxun Sangand were probed with the following primary antibodies: COL II (Abcam, ab34712), MMP13(Thermofisher, PA5-27242), PI3K (Starter, S0B0265), p-PI3K (Absin, abs130868), AKT (Starter, S0B0114), p-AKT (Absin, abs130890),

(4) Amelogenin Null Mice Develop Osteoarthritis, While Its Application Mitigates Disease Phenotypes in a Rat ModelFASEB JJuly 31, 2025Omer Helwa-Shalom, Yarden Kahlon-Suki, Shany Ivon Markowitz, Koby Goren, Dekel Shilo, Shira Schoonmaker, Chen Yochanan, Yechiel N. Gellman, Shaul Beyth, Dan Deutsch, et al.(MILESTONE) solution; (ii) immunohistochemical staining for MMP‐13 was performed using the primary antibody (PA5‐27242 Invitrogen) and secondary antibody (ZUC032 Zytomed); and (iii) immunohistochemical staining for amelogenin

(5) Amelogenin Null Mice Develop Osteoarthritis, While Its Application Mitigates Disease Phenotypes in a Rat ModelFASEB JJuly 18, 2025Omer Helwa‐Shalom, Yarden Kahlon‐Suki, Shany Ivon Markowitz, Koby Goren, Dekel Shilo, Shira Schoonmaker, Chen Yochanan, Yechiel N. Gellman, Shaul Beyth, Dan Deutsch, et al.(MILESTONE) solution; (ii) immunohistochemical staining for MMP‐13 was performed using the primary antibody (PA5‐27242 Invitrogen) and secondary antibody (ZUC032 Zytomed); and (iii) immunohistochemical staining for amelogenin

(6) Alleviating the IL-1β-stimulated extracellular matrix degradation in osteoarthritis, and chondrocyte inflammation by Morinda officinalis polysaccharide via the SIRT6/NF-κB pathwayBiomolecules and BiomedicineJuly 1, 2025Dongfang Zhao, Shuqin Xing, Jiao Qi, Zhiqiang Wei, Jianghai Huang, Jigao Sun, Xinzhu Wen, Yafei WangALPHA 1 chain (COL2A1, 1:1000; PA5-99159, Invitrogen), matrix metalloproteinase 13 (MMP13, 1:2000; PA5-27242, Invitrogen), a disintegrin and metalloproteinase with thrombospondin motifs 5 (ADAMTS5, 1:1000; PA5-14350,

(7) Unveiling the role of TCF19 in intervertebral disc degeneration with single-cell and bulk RNA sequencingScientific reportsMay 8, 2025He X, Wu L, Zhou H.used: anti-Collagen X from Invitrogen (catalog #PA5-115039) and anti-MMP13 from Invitrogen (catalog #PA5-27242). The following secondary antibodies were used: Goat anti-Rabbit 488 IgG from Invitrogen (catalog #A-11008). Real-time

(8) Regulating macrophage phenotypes with IL4I1-mimetic nanoparticles in IDD treatmentJournal of nanobiotechnologyMarch 6, 2025Luo J, Jin G, Cui S, Wang H, Liu Q.(1:500; ThermoFisher, MA3-16888), ADAMTS5 (1:500; ThermoFisher, PA5-27165), MMP13 (1:500; ThermoFisher, PA5-27242), IL4I1 (1:500; ThermoFisher, PA5-113266), and GAPDH (1:10000; ThermoFisher, AM4300) were added and

(9) Hybrid Nanoparticle Engineered with Transforming Growth Factor -β1-Overexpressed Extracellular Vesicle and Cartilage-Targeted Anti-Inflammatory Liposome for OsteoarthritisACS NanoDecember 17, 2024Jun Yong Kim, Won-Kyu Rhim, Seung Yeon Lee, Jung Min Park, Duck Hyun Song, Seung-Gyu Cha, Sang-Hyuk Lee, Dong-Youn Hwang, Byoung Ju Kim, Seungsoo Rho, et al.Apo-A1 (Santa Cruz Biotechnology, CA, USA), Col2A1 (sc-52658, Santa Cruz Biotechnology, CA, USA), MMP13 (PA5–27242, Thermo Fisher Scientific, OH, USA), and β-actin (sc-47778, Santa Cruz Biotechnology, CA, USA), respectively.

(10) Immune regulatory and anti-resorptive activities of tanshinone IIA sulfonate attenuates rheumatoid arthritis in miceBritish journal of pharmacologyDecember 1, 2024Panwar P, Andrault PM, Saha D, Brömme D.

(11) Functionally improved mesenchymal stem cells via nanosecond pulsed electric fields for better treatment of osteoarthritisJournal of orthopaedic translationJuly 1, 2024Lin J, Li K, Yang Z, Cao F, Gao L, Ning T, Xing D, Zeng H, Liu Q, Ge Z, et al.fast green and immunohistochemical staining (Collagen II (1: 400; ab34712, Abcam) or MMP13 (1: 500; PA5-27242, ThermoFisher)). The severity of cartilage degeneration was evaluated using Mankin scoring system (Table

(12) Modulation of early osteoarthritis by tibiofemoral re-alignment in sheepOsteoarthritis and cartilageJune 1, 2024Reinhard J, Oláh T, Laschke MW, Goebel LKH, Schmitt G, Speicher-Mentges S, Menger MD, Cucchiarini M, Pape D, Madry H.

(13) IRF1 governs the expression of SMARCC1 via the GCN5-SETD2 axis and actively engages in the advancement of osteoarthritisJournal of orthopaedic translationMarch 1, 2024Wang D, Zhang Y, Zhang L, He D, Zhao L, Miao Z, Cheng W, Zhu C, Zhu L, Zhang W, et al.(ab96183, Abcam), iNOS (ab178945, Abcam), Collagen II (MA5-12789, Thermo Fisher Scientific), MMP13 (#PA5-27242, Thermo Fisher Scientific), and GAPDH (ab8245, Abcam) overnight at 4 °C. Afterward, the membrane was

(14) CircSFMBT2-OA alleviates chondrocyte apoptosis and extracellular matrix degradation through repressing NF-κB/NLRP3 inflammasome activationHeliyonJune 1, 2023He A, Liu Y, Zhang R, Mao Y, Liu W.(Thermo Fisher Scientific), membranes were incubated with primary antibodies against MMP-13 (1:2000, PA5-27242, Thermo Fisher Scientific), ADAMTS-5 (1:1000, PA5-14350, Thermo Fisher Scientific), Collagen II (1:2000,

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MMP13 Antibody

MMP13 Antibody from Thermo Fisher Scientific

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MMP13 Antibody from Thermo Fisher Scientific

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