ACE2 Antibody 4355S from Cell Signaling Technology

Product Specs
ItemACE2 Antibody
CompanyCell Signaling Technology
Price $306.00 Inquire
Catalog Number4355S
Quantity100 µl
ApplicationsW, IP
ReactivityH
TargetACE2
HostRabbit
NCBI Full Gene Nameangiotensin converting enzyme 2
NCBI Gene AliasesACEH
ClonalityPolyclonal
Research AreaProtein Folding and Trafficking

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Cell Signaling Technology

3 Trask Lane

Danvers, Massachusetts 01923

United States

Phone: 877-616-CELL
Phone: 978-867-2388
Fax: 866-432-6112
Fax: 978-867-2488

Company Profile

Website: http://www.cellsignal.com/

Website: Technical Support

(1) SARS-CoV-2 ORF3a blocks lysosomal cholesterol egress by disrupting VPS39-regulated NPC2 trafficking and BMP metabolismCell ReportsJune 23, 2026Baley A. Goodson, Valeria Montenegro Montenegro Vazquez, Aliza Doyle, Oralia M. Kolaczkowski, Rui Liu, Jingyue Jia, Morié Ishida, Chunyan Ye, Alison M. Kell, Steven B. Bradfute, et al.RESOURCE,SOURCE,IDENTIFIER Antibodies,Antibodies,Antibodies ABHD6,Protein Tech,RRID:AB_2878694; 20494-1-AP ACE2,Cell signaling technologies,RRID: AB_2797606; 4355 ATG5,Protein Tech,RRID:AB_2062045; 10181-2-AP ATG7,ThermoFisher Scientific,RRID: AB_2809507; MA5-32221 Calnexin,Cell Signaling Technologies

(2) Targeting PTP4A3 with KVX-053 mitigates alcohol-amplified SARS-CoV-2 spike protein–induced acute lung injuryFrontiers in PharmacologyJune 19, 2026Pavel A. Solopov, Ruben Manuel Luciano Colunga Biancatelli, Elizabeth R. Sharlow, John S. Lazo, John D. Catravas(Cell Signaling, #9145S), total STAT3 (#4904S), phospho-IκBα (#2859S), total IκBα (#9242S), NLRP3 (#15101), ACE2 (#4355), and β-actin (loading control, Invitrogen, #3290431), followed by IRDye-conjugated secondary antibodies.

(3) Skin as a Potential Entry Point for SARS-CoV-2 VirusInt J Mol SciJune 15, 2026Dimitri Trubetskoy, Patrick Grudzien, Daria Chudakova, Anna Klopot, Bo Shi, Pankaj Bhalla, Bethany Perez White, Irina Budunovatwo-tailed Welch’s t-test. We used following antibodies for Western blot analyses: ACE2 (Cell Signaling #4355S, Cell Signaling, Danvers, MA, USA), TMPRSS2 (#sc515727, Santa Cruz, Dallas, TX, USA), GAPDH (Cell Signaling

(4) SKIN AS A POTENTIAL ENTRY POINT FOR SARS-COV-2bioRxivApril 11, 2026Dmitry Trubetskoy, Patrick Grudzien, Daria A. Chudakova, Anna Klopot, Bo Shi, Pankaj Bhalla, Bethany Perez White, Irina Budunovatwo-tailed Welch’s t-test. We used following antibodies for Western blot analyses: ACE2 (Cell Sig #4355S, Cell Signaling, Danvers, MA, USA), TMPRSS2 (#sc515727, Santa Cruz, Dallas, TX, USA), GAPDH (Cell Sig

(5) Evolution of a truncated nucleocapsid protein enhances SARS-CoV-2 fitness by suppressing antiviral responsesPLoS BiolApril 1, 2026Rory P. Mulloy, Danyel Evseev, Noga Sharlin, Maxwell P. Bui-Marinos, Émile Lacasse, Isabelle Dubuc, Louis Flamand, Jennifer A. CorcoranAntibody,Species,Vendor/Catalog #,Application,Dilution ACE2,Rabbit,CST/4355S,Immunoblot,"1:1,000" Actin-HRP conjugated,Rabbit,CST/5125S,Immunoblot,"1:10,000" FLAG,Chicken,Abcam/ab1170,Immunofluorescence,1:100 FLAG,Mouse,CST/8146S,ImmunoblotImmunoprecipitation,"1:1,0001:1,000" FLAG,Rabbit,CST/14793T,ImmunoblotImmunofluorescence,"1:1,0001:1,000" G3BP1,Mouse,BD/611126,ImmunoblotImmunofluorescence,"1:1,0001:1,000" Hedls,Mouse,Santa

(6) Ursodeoxycholic Acid Attenuates B Cell Susceptibility to SARS-CoV-2 Spike Protein by Interfering Its Binding to ACE2Biomolecules & TherapeuticsNovember 1, 2025So-Jeong Park, Eun-Yi MoonCellTiter-Glo® Luminescent cell viability assay kit (G9241) was purchased from Promega Co. (Madison, WI, USA). Antibody to ACE2 (4355S) were obtained from Cell signaling Technology (Beverly, MA USA). Antibody which is reactive with LC3

(7) ACE2 from Pipistrellus abramus bats is a receptor for HKU5 coronavirusesNat CommunMay 28, 2025Nicholas J. Catanzaro, Ziyan Wu, Chengcheng Fan, Victoria Jefferson, Anfal Abdelgadir, Alexandra Schäfer, Boyd L. Yount, Pamela J. Bjorkman, Ralph Baric, Michael LetkoHuh-7.5 ACE2/DPP4 double KO cells with the following antibodies: ACE2 (Cell Signaling Technology - 4355S, 1:2000), DPP4 (Cell Signaling Technology - 67138S, 1:2000), APN (Cell Signaling Technology - 1372S,

(8) AI Promoted Virtual Screening, Structure-Based Hit Optimization, and Synthesis of Novel COVID-19 S-RBD Domain InhibitorsJournal of Chemical Information and ModelingNovember 25, 2024Ioannis Gkekas, Sotirios Katsamakas, Stelios Mylonas, Theano Fotopoulou, George Ε. Magoulas, Alia Cristina Tenchiu, Marios Dimitriou, Apostolos Axenopoulos, Nafsika Rossopoulou, Simona Kostova, et al.(aa19–615) was verified by Western Blotting using an anti-Spike (69323, CST) and an anti-ACE2 antibody (4355, CST), respectively. GAPDH was used as loading control and was detected with a rabbit anti-GAPDH antibody

(9) Lung‐Targeted Lipid Nanoparticle‐Delivered siUSP33 Attenuates SARS‐CoV‐2 Replication and Virulence by Promoting Envelope DegradationAdvanced ScienceNovember 1, 2024Yuzheng Zhou, Yujie Liao, Lujie Fan, Xiafei Wei, Qiang Huang, Chuwei Yang, Wei Feng, Yezi Wu, Xiang Gao, Xiaotong Shen, et al.anti‐SARS‐CoV‐2 NSP3 monoclonal antibody (CST, 88 086); Rabbit anti‐hACE2 polyclonal antibody (CST, 4355); Goat anti‐Rabbit and anti‐Mouse HRP Conjugated secondary antibodies (TransGen Biotech); Goat anti‐Rabbit

(10) Dandelion root extracts and taraxasterol inhibit LPS‑induced colorectal cancer cell viability by blocking TLR4‑NFκB‑driven ACE2 and TMPRSS2 pathwaysExperimental and Therapeutic MedicineApril 19, 2024Kerry Yang, Yuehong WangCell Signaling Technology, Inc.), NFκB-p65 (cat. no. 8242; 1:1,000; Cell Signaling Technology, Inc.), ACE2 (cat. no. 4355; 1:1,000; Cell Signaling Technology, Inc.), TMPRSS2 (cat. no. PAB11593; 1:1,000; Abnova) and GAPDH (cat.

(11) Herbal Compounds Dauricine and Isoliensinine Impede SARS-CoV-2 Viral EntryBiomedicinesOctober 27, 2023Dabrell SN, Li YC, Yamaguchi H, Chen HF, Hung MC.with an enhanced chemiluminescence (ECL) substrate. Primary antibodies used in this study were ACE2 (4355S; Cell Signaling Technology, Danvers, MA, USA), flag (MA1-91878; Invitrogen, Carlsbad, CA, USA), and

(12) P21-activated kinase 1 (PAK1)-mediated cytoskeleton rearrangement promotes SARS-CoV-2 entry and ACE2 autophagic degradationSignal Transduction and Targeted TherapyOctober 9, 2023Ming Liu, Bingtai Lu, Yue Li, Shuofeng Yuan, Zhen Zhuang, Guangyu Li, Dong Wang, Liuheyi Ma, Jianheng Zhu, Jinglu Zhao, et al.were used for western blot, immunofluorescence and flow cytometry: anti-human ACE2 antibody (CST, Cat#4355S), HRP conjugated anti-Flag antibody (Sigma-Aldrich, Cat#A8592), HRP conjugated anti-Myc antibody (CST,

(13) The anti-SARS-CoV-2 effect and mechanism of Chiehyuan herbal oral protection solutionHeliyonJuly 1, 2023Wu CY, Yang YH, Lin YS, Shu LH, Cheng YC, Liu HT, Lin YY, Lee IY, Shih WT, Yang PR, et al.temperature. The enlisted primary antibodies included: anti-ACE2 antibody (1:1000, Cell Signaling, #4355) and anti-GAPDH antibody (1:10000, GeneTex, GTX100118). Both primary and secondary antibodies were diluted

(14) Targeting 2-Oxoglutarate–Dependent Dioxygenases Promotes Metabolic Reprogramming That Protects against Lethal SARS-CoV-2 Infection in the K18-hACE2 Transgenic Mouse ModelImmunoHorizonsJuly 1, 2023Forrest Jessop, Benjamin Schwarz, Eric Bohrnsen, Molly Miltko, Carl Shaia, Catharine M. BosioCell Signaling Technology). ACE2 was quantified in A549 cell lysates (using anti–ACE-2 Ab, catalog no. 4355S, Cell Signaling Technology) using a ProteinSimple Wes microcapillary Western blot. Total protein levels

(15) Interferon-inducible phospholipids govern IFITM3-dependent endosomal antiviral immunityThe EMBO journalMay 15, 2023Unali G, Crivicich G, Pagani I, Abou-Alezz M, Folchini F, Valeri E, Matafora V, Reisz JA, Giordano AMS, Cuccovillo I, et al.monoclonal Ab (1:5,000, proteintech Cat# 60074‐1‐Ig), rabbit anti‐ACE2 (1:1,000, Cell Signaling Technology 4355S), rabbit anti‐HA tag antibody—ChIP Grade (1:10,000 Abcam Cat# ab9110), mouse anti‐his (1:10,000 Millipore

(16) The Screening of Broadly Neutralizing Antibodies Targeting the SARS-CoV-2 Spike Protein by mRNA Immunization in MicePharmaceuticsMay 5, 2023Zhiyin An, Yu Zhang, Xiang Yu, Jia Xia, Yanan Yin, Guoming Li, Jing Lu, Xuemei Fan, Yingjie XuChina), the mouse β-actin antibody (66009; Proteintech, Wuhan, China), and the rabbit-ACE2 antibody (4355; Cell Signaling technology, Danvers, MA, USA). 2.9. Cryo-TEM Sample Preparation and Imaging A glow-discharged

(17) The SARS-CoV-2 Spike Protein Activates the Epidermal Growth Factor Receptor-Mediated SignalingVaccines (Basel)March 30, 2023Abdul Rasheed Palakkott, Aysha Alneyadi, Khalid Muhammad, Ali Hussein Eid, Khaled M. A. Amiri, Mohammed Akli Ayoub, Rabah IratniERK1/2 (Cat. # 4695), phospho-AKT (Cat. # 9271), AKT (Cat. # 9272), Survivin (Cat. # 2803), ACE2 (Cat. # 4355), anti-mouse (Cat. # 7076), and anti-rabbit (Cat. # 7074) were purchased from Cell Signaling, Technology,

(18) Targeting ACE2-BRD4 crosstalk in colorectal cancer and the deregulation of DNA repair and apoptosisNPJ precision oncologyFebruary 18, 2023Zhang S, Kapoor S, Tripathi C, Perez JT, Mohan N, Dashwood WM, Zhang K, Rajendran P, Dashwood R.antibodies for BRD4 (1:1000, #E2A7X), c-Myc (1:1000, #D3N8F), PARP (1:1000, #9542) and ACE2 (1:1000, #4355) from Cell Signaling (Danvers), pH2AX Ser139 (Santa Cruz, 1:1000, #101696), pRPA32 S4/S8 (Bethyl Laboratories,

(19) SARS-CoV-2 seroassay optimization and performance in a population with high background reactivity in MalimedRxivSeptember 27, 2022Issaka Sagara et al.The expression was further confirmed by western blot using ACE2 Antibody (Cell Signaling Technology, #4355). VSVdG-EGFP-SARS2-Sgp virus production To generate non-replicative self-reporting VSVdG-EGFP-SARS2-Sgp,

(20) Suppression of ACE2 SUMOylation protects against SARS-CoV-2 infection through TOLLIP-mediated selective autophagyNature communicationsSeptember 3, 2022Jin S, He X, Ma L, Zhuang Z, Wang Y, Lin M, Cai S, Wei L, Wang Z, Zhao Z, et al.K48-linkage specific polyubiquitin antibody (#4289), anti-ULK1 (D8H5) [#8054], anti-ATG13 (E1Y9V) [#13468], anti-ACE2 (#4355), anti-EEA1 (C45B10) [#3288], and anti-Rab7 (D95F2) [#9367] were purchased from Cell Signaling Technology.

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ACE2 Antibody

ACE2 Antibody from Cell Signaling Technology

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ACE2 Antibody from Cell Signaling Technology

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