EphA3/A4/A5 (D2C11) Rabbit mAb 8793S from Cell Signaling Technology

Product Specs
ItemEphA3/A4/A5 (D2C11) Rabbit mAb
CompanyCell Signaling Technology
Price $339.00 Inquire
Catalog Number8793S
Quantity100 µl
ApplicationsW, IP
ReactivityH, M
TargetEphA5;EphA3;EphA4
IsotypeIgG
HostRabbit
NCBI Full Gene NameEPH receptor A5, EPH receptor A4, EPH receptor A3
ModificationsEphA3 (Tyr779) phosphate
CloneD2C11
Molecular Weight135
ClonalityMonoclonal
NCBI Gene AliasesEK4, HEK4, HEK7, HEK8, TYRO1, EK8, EHK1, EHK-1, TYRO4, EK7, ETK, ETK1, SEK, CEK7, HEK
Research AreaRTK

Questions and Answers

Can this antibody be used to study the role of EphA3 in prostate cancer?

Yes, the EphA3/A4/A5 (D2C11) Rabbit mAb has been utilized in research related to prostate cancer. Specifically, it was mentioned in a study where the knockdown of prostate-specific antigen (PSA) led to the down-regulation of EPHA3, indicating its involvement in the tumorigenesis and progression of prostate cancer cells (C4-2) in vitro and in vivo ().

What applications is this antibody suitable for in my experiments?

The EphA3/A4/A5 (D2C11) Rabbit mAb is suitable for Western blotting and immunoprecipitation. These applications allow for the detection and analysis of total EphA3, EphA4, and EphA5 proteins, which are crucial for studying receptor tyrosine kinase signaling pathways.

Is this antibody reactive with both human and mouse samples?

Yes, this antibody is reactive with both human (Homo sapiens) and mouse (Mus musculus) samples, making it versatile for comparative studies across species in cell biology research.

How has this antibody been validated in scientific literature?

The EphA3/A4/A5 (D2C11) Rabbit mAb has been cited in multiple scientific articles, indicating its reliability in research. For instance, it was used in a study that explored the protein-protein interactions involving EPHA3, contributing to the understanding of its role in prostate cancer progression ().

Cell Signaling Technology

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Danvers, Massachusetts 01923

United States

Phone: 877-616-CELL
Phone: 978-867-2388
Fax: 866-432-6112
Fax: 978-867-2488

Company Profile

Website: http://www.cellsignal.com/

Website: Technical Support

(1) The YAP1 and EPHA3 receptor tyrosine kinase axis regulates cellular plasticity and treatment responseCellular SignallingMay 1, 2026Marwah M. Al-Mathkour, Abdulrahman M. Dwead, Kezhan Khazaw, Bekir Cinaranalysis. IHC staining was performed with human EPHA3, Rabbit mAb (Cell Signaling Technology (CST), Cat# 8793, 1:200 dilution) and human YAP1, Rabbit mAb (CST, Cat#14074, 1:200 dilution) as instructed by the manufacturer.

(2) The Hippo effector YAP1/TEAD1 regulates EPHA3 expression to control cell contact and motilityScientific reportsMarch 9, 2022Al-Mathkour MM, Dwead AM, Alp E, Boston AM, Cinar B.The membranes were probed with the primary antibody to EPHA3/A4/A5 (Cell Signaling Technology (CST, #8793, 1:1000), SCBT (sc-514209, 1:100), phospho-EPHA3 (Tyr779) (CST, #8862, 1:1000), YAP1 (CST, #8418 and

(3) Comprehensive role of prostate-specific antigen identified with proteomic analysis in prostate cancerJournal of cellular and molecular medicineSeptember 1, 2020Li H, Ma Z, Che Z, Li Q, Fan J, Zhou Z, Wu Y, Jin Y, Liang P, Che X.(Cat. No. PA5‐24128, Thermo Fisher, USA), RAD51C (Cat. No. sc‐390697, SANTA CRUZ, USA), EPHA3 (Cat. No. 8793, CST, USA) and β‐Actin mouse monoclonal antibody (Cat. No. 3700, CST, USA). Secondary antibodies were

(4) Ephrin-B2 paces neuronal production in the developing neocortexBMC developmental biologyMay 13, 2020Kischel A, Audouard C, Fawal MA, Davy A.Rabbit, 9661, 1/300. Eph B2: R & D Systems, Goat, AF467, WB: 1/1000. Eph A4: Cell signaling, Rabbit, 8793, WB: 1/2000. P-Eph B1–2: Abcam, Rabbit, ab61791, WB: 1/1000. P-Eph A4: Gift from Greenberg’s lab, Harvard

(5) Enhanced efficacy of sitravatinib in metastatic models of antiangiogenic therapy resistancePloS oneJanuary 1, 2019Dolan M, Mastri M, Tracz A, Christensen JG, Chatta G, Ebos JML.Cell Signaling (phospho-MET, 3126; phospho-EphA2, 12677; phospho-EphA3, 8862; MET, 3127; EphA2, 6997; EphA3, 8793), R&D systems (phospho-AXL, AF2228-SP; AXL, AF854-SP), and Sigma-Aldrich (α-tubulin, T6074). Uncropped

(6) Factors Influencing Business Intelligence Data Collection StrategiesThe Indonesian Journal of Accounting ResearchMay 23, 2017Hanif Faidz Rahadian, Dekar Urumsah4 Composite Reliability dan Cronbach's Alpha CMP 0,8265 0,7321 Information Reliable COM 0,9172 0,8793 Reliable CST 0,9109 0,8644 Reliable INS 0,8911 0,8329 Reliable ISI 0,9246 0,8905 Reliable OTR 0,9279 0,8958 Reliable PBD 0,8917 0,8633 Reliable Code

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EphA3/A4/A5 (D2C11) Rabbit mAb

EphA3/A4/A5 (D2C11) Rabbit mAb from Cell Signaling Technology

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Questions and Answers

Cell Signaling Technology

Citations (6)

Reviews

EphA3/A4/A5 (D2C11) Rabbit mAb from Cell Signaling Technology

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