beta-TrCP (D12C8) Rabbit mAb 11984S from Cell Signaling Technology

Product Specs
Itembeta-TrCP (D12C8) Rabbit mAb
CompanyCell Signaling Technology
Price $339.00 Inquire
Catalog Number11984S
Quantity100 µl
ApplicationsW
ReactivityH, M, R, Mk
Targetbeta-Trcp
Molecular Weight62
HostRabbit
NCBI Full Gene Namebeta-transducin repeat containing E3 ubiquitin protein ligase
NCBI Gene AliasesBETA-TRCP, FBW1A, FBXW1, FBXW1A, FWD1, bTrCP, bTrCP1, betaTrCP
ClonalityMonoclonal

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Cell Signaling Technology

3 Trask Lane

Danvers, Massachusetts 01923

United States

Phone: 877-616-CELL
Phone: 978-867-2388
Fax: 866-432-6112
Fax: 978-867-2488

Company Profile

Website: http://www.cellsignal.com/

Website: Technical Support

(1) SelK promotes glioblastoma cell proliferation by inhibiting β-TrCP1 mediated ubiquitin-dependent degradation of CDK4Journal of Experimental & Clinical Cancer ResearchAugust 19, 2024Jizhen Li, Lingling Zhao, Zerui Wu, Shirui Huang, Junyu Wang, Yuanyuan Chang, Li Liu, Honglei Jin, Jianglong Lu, Chuanshu Huang, et al.purchased from Santa Cruz Biotechnology (Santa Cruz, CA, USA). Antibodies specific against β-TrCP1 (11984S), SKP2 (2652S), P-PERK (3179S), HA (3724S), Myc (2276S), ATF4 (11815S), and P-eIF2α (Ser51,3597S) were

(2) Casein kinase 1α mediates phosphorylation of the Merkel cell polyomavirus large T antigen for β-TrCP destruction complex interaction and subsequent degradationmBioAugust 14, 2024Alexander M. Pham, Hyun Jin Kwun(Cell Signaling, 2655), HA (Cell Signaling, 3724), β-actin (Cell Signaling, 4970), β-TrCP (Cell Signaling, 11984), Skp2 (Cell Signaling, 2652), and alpha-tubulin (DSHB, 12G10). Cycloheximide chase assay HEK293 cells

(3) HPV infection alters vaginal microbiome through down-regulating host mucosal innate peptides used by Lactobacilli as amino acid sourcesNature communicationsFebruary 28, 2022Lebeau A, Bruyere D, Roncarati P, Peixoto P, Hervouet E, Cobraiville G, Taminiau B, Masson M, Gallego C, Mazzucchelli G, et al.(1/1000, clone E247, Abcam), anti-CK1 (1/1000, #2655, Cell Signaling Technology), anti-β-TrCP (1/1000, #11984, Cell Signaling Technology), anti-phospho-β-catenin (1/1000, Ser45, #9564, Cell Signaling Technology),

(4) Crotonylation sensitizes IAPi-induced disruption of latent HIV by enhancing p100 cleavage into p52iScienceJanuary 21, 2022Dajiang Li, Morgan G. Dewey, Li Wang, Shane D. Falcinelli, Lilly M. Wong, Yuyang Tang, Edward P. Browne, Xian Chen, Nancie M. Archin, David M. Margolis, et al.signaling,Cat#3017 anti-RelB,Cell signaling,Cat#10544 anti-AceS1 (ACSS2),Cell signaling,Cat#81464 anti-β-TrCP,Cell signaling,Cat#11984 anti-β-actin,Cell signaling,Cat#4970 anti-Caspase-3,Cell signaling,Cat#9662 normal rabbit IgG,Cell signaling

(5) SIRT4-Catalyzed Deacetylation of Axin1 Modulates the Wnt/β-Catenin Signaling PathwayFrontiers in oncologyJanuary 1, 2022Wang Y, Yue J, Xiao M, Lu X, Chin YE.anti-β-TrCP antibody (Cell Signaling Technology, 4394); anti-β-TrCP antibody (Cell Signaling Technology, 11984) and anti-dishevelled 2 antibody (Abcam, ab228804); anti-GSK3β antibody (Cell Signaling Technology,

(6) TRIB2 modulates proteasome function to reduce ubiquitin stability and protect liver cancer cells against oxidative stressCell death & diseaseJanuary 7, 2021Guo S, Chen Y, Yang Y, Zhang X, Ma L, Xue X, Qiao Y, Wang J.1:1000), anti-K48-Ub (8081, 1:1000), anti-K63-Ub (5621, 1:1000), anti-LAMP2 (49067, 1:1000), anti-βTrCP (11984, 1:1000), anti-POMP (15141, 1:1000), anti-HIF1α (36169, 1:1000), anti-HIF1α-OH (3434, 1:1000), and anti-MYPT1

(7) Coiled-Coil Domain-Containing 68 Downregulation Promotes Colorectal Cancer Cell Growth by Inhibiting ITCH-Mediated CDK4 DegradationFrontiers in oncologyJanuary 1, 2021Wang C, Li H, Wu L, Jiao X, Jin Z, Zhu Y, Fang Z, Zhang X, Huang H, Zhao L.Santa Cruz Biotechnology (Santa Cruz, CA, USA). Antibodies against CDC37 (4793S), cyclin E2 (4132S), HA (3724S), BTRC (11984S), and RXRα (3085S) were purchased from Cell Signaling Technology (Boston, MA, USA). Antibodies against

(8) Low-Dose Decitabine Augments the Activation and Anti-Tumor Immune Response of IFN-γ(+) CD4(+) T Cells Through Enhancing IκBα Degradation and NF-κB ActivationFrontiers in cell and developmental biologyJanuary 1, 2021Li X, Dong L, Liu J, Wang C, Zhang Y, Mei Q, Han W, Xie P, Nie J.(2697)/IKKβ (8943), phosphor-IκBα Ser32 (2859)/IκBα (9242), phosphor-p65 Ser536 (3031)/p65 (6956), β-TrCP (11984), β-actin (3700). Anti-SP1 antibody was purchased from Abcam (ab157123). The relevant secondary antibodies

(9) Rotavirus NSP1 Requires Casein Kinase II-Mediated Phosphorylation for Hijacking of Cullin-RING LigasesmBioAugust 29, 2017Davis KA, Morelli M, Patton JT.NSP1 proteins (4) and PCNA (sc-7907; Santa Cruz Biotech [SCB]), rabbit monoclonal antibody to β-TrCP (11984S; Cell Signaling Technology, Inc. [CST]), and mouse monoclonal antibodies to IκB (4814; CST), p-IκB (9246;

(10) Dalbinol, a rotenoid from Amorpha fruticosa L., exerts anti-proliferative activity by facilitating β-catenin degradation in hepatocellular carcinoma cellsOncotargetJuly 18, 2017Zhu X, Wu X, Cheng J, Liao H, Di X, Li L, Li R, Zhou Y, Zhang X.(#5453), Bim (#2933), Bax (#5023), Ubiquitin (#3936), β-catenin (#8480), GSK-3β (pSer9) (#9322), β-TrCP (#11984) and β-actin (#3700) were from Cell Signaling Technology (Danvers, MA, USA). Protein A/G PLUS-Agarose

(11) MLL-AF4 binds directly to a BCL-2 specific enhancer and modulates H3K27 acetylationExperimental HematologyMarch 1, 2017Laura Godfrey et al.PBX1/2/3 (Santa Cruz, sc888 lot J0212), cleaved PARP (Cell Signaling 5625), and β-TrCP (Cell Signaling 11984). Nascent RNA-seq Cells (108) were treated with 500 μmol/L 4-thiouridine (4-SU) for 1 hour. Cells

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Frontiers in oncology

beta-TrCP (D12C8) Rabbit mAb from Cell Signaling Technology

Cell Signaling Technology

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beta-TrCP (D12C8) Rabbit mAb from Cell Signaling Technology

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