FKBP5 (D5G2) Rabbit mAb 12210S from Cell Signaling Technology

Product Specs
ItemFKBP5 (D5G2) Rabbit mAb
CompanyCell Signaling Technology
Price $339.00 Inquire
Catalog Number12210S
Quantity100 µl
ApplicationsW, IP
ReactivityH, M, R, Mk
ClonalityMonoclonal
TargetFKBP5
HostRabbit
NCBI Full Gene NameFKBP prolyl isomerase 5
NCBI Gene AliasesAIG6, FKBP51, FKBP54, P54, PPIase, Ptg-10
Research AreaProtein Folding and Trafficking
IsotypeIgG
CloneD5G2
Molecular Weight51

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Cell Signaling Technology

3 Trask Lane

Danvers, Massachusetts 01923

United States

Phone: 877-616-CELL
Phone: 978-867-2388
Fax: 866-432-6112
Fax: 978-867-2488

Company Profile

Website: http://www.cellsignal.com/

Website: Technical Support

(1) Vitamin D deficiency alters prostate epithelial differentiation and increases prostate cancer aggressiveness in ex vivo and in vivo modelsbioRxivFebruary 20, 2026Adriana Duraki, Kirsten D. Krieger, Sasha Celada, Robert A. Holt, Ryan M. Brown, Luyu Wang, Michael J. Schlicht, Maarten C. Bosland, Robert M. Sargis, Donald Vander Griend, et al.primary antibodies specific to VDR (D2K6W; CST 12550), AR (PG-21; EMD Millipore 06–680), FKBP5 (D5G2; CST 12210), and housekeeper H3 (96C10; CST 3638). All primary antibodies were diluted 1:1000 in blocking buffer

(2) FKBP51 disrupts the insulin signaling pathway and impairs mitochondrial bioenergetics in HepG2 cellsScientific ReportsFebruary 19, 2026Camila Donoso-Barraza, Melissa Díaz-Roblero, Carlos Sepúlveda, Anais Villegas-Bravo, Sandra A. Soto-Alarcón, Danitza Durán-Castillo, Valeska Castillo, Roberto Bravo-Sagua, Rodrigo TroncosoSDS-polyacrylamide gels and subjected to immunoblotting overnight using antibodies specific for FKBP51 (1:1000, 12210 S, Cell Signaling, Massachusetts, USA), Akt (1:2,000, 2920 S, Cell Signaling), phospho-Ser473 AKT (1:1000,

(3) FKBP5 regulates interferon signaling leading to myeloid cell activation in multiple sclerosisJournal of NeuroinflammationFebruary 10, 2026Cinthia Gonzalez Cruz, Jessica Gibson, Maggie Kita, Narendra V. Sankpal, Ignazio S. Piras, Claudia CantoniAfter blocking in 5% milk in TBST, primary antibodies FKBP5 (1:1000; Cell Signaling Technology (CST), 12210S, ULK (1:1000; CST, 8054), pULK (1:1000; CST, 5869), AKT (1:1000; CST, 9272), or LC3B (1:200; Santa Cruz

(4) Inhibition of FKBP5 alleviates obstetric antiphospholipid syndrome by regulating macrophage polarizationScientific ReportsNovember 21, 2025Mingjie Song, Juan Wang, Wenli Mu, Yanwei Zheng, Rongzhen Jiang, Yanjun Cai, Yincheng Teng, Yu Xialoading controls. The antibodies used in this investigation included the following: anti-FKBP5 antibody (#12210, CST, Danvers, USA), anti-iNOS antibody (#13120, CST, Danvers, USA), anti-Arg-1 antibody (#93668, CST,

(5) Germline–Somatic Liaison Dictates Cancer Subtypes via de novo Steroid BiosynthesisCancer DiscoveryOctober 6, 2025Paola Gasperini, Alessandro Alaimo, Blerta Stringa, Yoon-Mi Chung, Yari Ciani, Francesca Lorenzin, Giulia Fracassi, Yanis Zekri, Francesco Orlando, Orsetta Quaini, et al.2281105), NKX3.1 (Millipore, cat. # AB5983, RRID: AB_ 92188), FKBP5 (Cell Signaling Technology, cat. # 12210, RRID: AB_ 2797846), FIBRILLARIN (Abcam, cat. # ab4566, RRID: AB_304523), β-TUBULIN (Santa Cruz Biotechnology,

(6) Novel PROTAC to target FKBP12: the potential to enhance bone morphogenetic protein activity and apoptosis in multiple myelomaHaematologicaOctober 1, 2025Ingrid Quist-Lokken, Mira Tilseth, Clara Andersson-Rusch, Md Abu Hanif, Michael Walz, Johanna Fredrikke Nordstrand Moen, Megan Anne Vik, Tobias Schmidt Slordahl, Anders Sundan, Felix Hausch, et al.AB_2102847, #SC-133067, Santa Cruz, TX, USA), FKBP4 (RRID:AB_2797737, #11826), FKBP5 (RRID:AB_2797846, #12210) (Cell Signaling Technology, BioNordika AS, Oslo, Norway), and glyceraldehyde-3-phosphate dehydrogenase

(7) Psychological stress-induced systemic corticosterone directly sabotages intestinal stem cells and exacerbates colitisCell DiscovMay 13, 2025Xiaole Sheng, Lanfei Jin, Zhengrong Yao, Jiaji Gu, Longtao Zhu, Andi Huang, Junxuan Peng, Xin Xu, Xiaolong Ge, Wei Zhou, et al.(NR3C1) (Cell Signaling Technology, 12041S), mouse monoclonal anti-FKBP5 (Cell Signaling Technology, 12210S), rabbit polyclonal anti-Akt (Cell Signaling Technology, 9272S), rabbit monoclonal anti-phospho-Akt (Ser473

(8) Uncoupling of Akt and mTOR signaling drives resistance to Akt inhibition in PTEN loss prostate cancersSci AdvFebruary 7, 2025Ninghui Mao, Young Sun Lee, Nazifa Salsabeel, Zeda Zhang, Dan Li, Harmanpreet Kaur, Xiaoping Chen, Qing Chang, Sanjay Mehta, Jesse Barnes, et al.5262S), BIP (Cell Signaling Technology, 3177S), AR (Abcam, AB108341), FKBP5 (Cell Signaling Technology, 12210S), STEAP1 (Santa Cruz Biotechnology, SC-271872), and PMEPA1 (Santa Cruz Biotechnology, SC-293372). CellTiter-Glo–based

(9) NSD2 is a requisite subunit of the AR/FOXA1 neo-enhanceosome in promoting prostate tumorigenesisNature geneticsOctober 1, 2024Parolia A, Eyunni S, Verma BK, Young E, Liu Y, Liu L, George J, Aras S, Das CK, Mannan R, et al.(Cell Signaling Technologies: 92056 S, 1:1,000); KLK3/PSA (Dako:A0562, 1:1,000); FKBP5(Cell Signaling Technologies: 12210, 1:1,000); NKX3-1 (Cell Signaling Technologies:83700 S, 1:1,000); FOXA1 N-terminal (Cell Signaling Technologies:

(10) Dysregulation of Glucocorticoid Receptor Homeostasis and Glucocorticoid-Associated Genes in Umbilical Cord Endothelial Cells of Diet-Induced Obese Pregnant SheepInternational Journal of Molecular SciencesFebruary 15, 2024Eugenia Mata-Greenwood, Wendy L. Chow, Nana A. O. Anti, LeeAnna D. Sands, Olayemi Adeoye, Stephen P. Ford, Peter W. Nathanielsz,Cell Signaling Technology,12041,1:1000,95/90 FKBP prolyl isomerase 5 (FKBP5),Cell Signaling Technology,12210,1:1000,55 NFKB p65 subunit (RELA),Cell Signaling Technology,8242,1:1000,65 TATA binding protein (TBP),Proteintech,22006-1-AP,1:1000,38 Specificity

(11) FABP5 Inhibition against PTEN-Mutant Therapy Resistant Prostate CancerCancers (Basel)December 21, 2023Manojit M. Swamynathan, Grinu Mathew, Andrei Aziz, Chris Gordon, Andrew Hillowe, Hehe Wang, Aashna Jhaveri, Jude Kendall, Hilary Cox, Michael Giarrizzo, et al.39926), AR (Santa Cruz Biotechnology (Dallas, TX, USA), sc-7305), FKBP5 (Cell Signaling Technology, 12210S), NKX3.1 (Santa Cruz Biotechnology, sc-393190), β-Tubulin (Cell Signaling Technology, 2146), and Vinculin

(12) Mediobasal hypothalamic FKBP51 acts as a molecular switch linking autophagy to whole-body metabolismScience advancesMarch 11, 2022Häusl AS, Bajaj T, Brix LM, Pöhlmann ML, Hafner K, De Angelis M, Nagler J, Dethloff F, Balsevich G, Schramm KW, et al.rabbit polyclonal anti-FKBP51 (A301-430A, Bethyl Laboratories), rabbit monoclonal anti-FKBP5 (D5G2, #12210, Cell Signaling Technology), rabbit monoclonal anti-LKB1 (D60C5, #3047, Cell Signaling Technology),

(13) MicroRNA‑149 inhibits cancer cell malignant phenotype by regulating Akt1 in C4‑2 CRPC cell lineOncology reportsDecember 1, 2021Zhao J, Li Q, Feng B, Wei D, Han Y, Li M, Wang Y, Luo Y, Jiang Y.Cell Signaling Technology, Inc.), PSA (1:1,000; cat. no. 5365; Cell Signaling Technology, Inc.), FKBP5 (1:1,000; cat. no. 12210; Cell Signaling Technology, Inc.), E-cadherin (1:1,000; cat. no. sc-8426; Santa Cruz Biotechnology, Inc

(14) Selective inhibitors of mTORC1 activate 4EBP1 and suppress tumor growthNature chemical biologyOctober 1, 2021Lee BJ, Boyer JA, Burnett GL, Thottumkara AP, Tibrewal N, Wilson SL, Hsieh T, Marquez A, Lorenzana EG, Evans JW, et al.anti-mTOR #2972, anti-β-actin (8H10D10) #3700, anti-HATag (C29F4) #3724, anti-FKBP51 (FKBP5) (D5G2) #12210 all from Cell Signaling Technologies (Danvers, MA, USA); anti-rpS6 (C-8) #sc-74459 from Santa Cruz Biotechnologies

(15) Stress-primed secretory autophagy promotes extracellular BDNF maturation by enhancing MMP9 secretionNature communicationsJuly 30, 2021Martinelli S, Anderzhanova EA, Bajaj T, Wiechmann S, Dethloff F, Weckmann K, Heinz DE, Ebert T, Hartmann J, Geiger TM, et al.Rockland, 600-401-383), FKBP51 (1:1000, Bethyl, A301-430A), FKBP5 (D5G2) (1:1000, Cell Signaling, #12210), Actin (1:5000, Santa Cruz Biotechnology, sc-1616), GAPDH (1:8000, Millipore CB1001), TRIM16 (1:1000,

(16) Fasting-induced FOXO4 blunts human CD4(+) T helper cell responsivenessNature metabolismMarch 1, 2021Han K, Singh K, Rodman MJ, Hassanzadeh S, Wu K, Nguyen A, Huffstutler RD, Seifuddin F, Dagur PK, Saxena A, et al.(T172),Cell Signaling,Cat. #2535S; RRID:AB_331250 Rabbit polyclonal anti-FKBP5,Cell Signaling,Cat. #12210S; RRID:AB_2797846 Rabbit polyclonal anti-FOXO4,Cell Signaling,Cat. #9472S; RRID:AB_10831833 Rabbit

(17) Dexamethasone and Glucocorticoid-Induced Matrix Temporally Modulate Key Integrins, Caveolins, Contractility, and Stiffness in Human Trabecular Meshwork CellsInvestigative Opthalmology & Visual ScienceNovember 10, 2020Felix Yemanyi, Hasna Baidouri, Alan R. Burns, VijayKrishna RaghunathanAntibody,Catalog Number,"Stock Concentration, µg/mL",Dilution,"Final Concentration, µg/mL",Source FKBP5,12210,918.0,1/5000,0.184,"Cell Signaling Technology, Danvers, MA, USA" αV Integrin,4711,53.0,1/2000,0.027, β1

(18) Moderate Aerobic Exercise Training Prevents the Augmented Hepatic Glucocorticoid Response Induced by High-Fat Diet in MiceInternational Journal of Molecular SciencesOctober 14, 2020Jonatan Dassonvalle, Francisco Díaz-Castro, Camila Donoso-Barraza, Carlos Sepúlveda, Francisco Pino-de la Fuente, Pamela Pino, Alejandra Espinosa, Mario Chiong, Miguel Llanos, Rodrigo Troncosopolyvinylidene fluoride (PVDF) membranes (0.45 µm). The primary antibodies and their dilution were FKBP5 1:1000 (12210S, Cell Signaling), G6Pase 1:500 (83690, Abcam, Cambridge, United Kingdom), and GAPDH 1:5000 (MAB374,

(19) Splicing factor PRPF6 upregulates oncogenic androgen receptor signaling pathway in hepatocellular carcinomaCancer scienceOctober 1, 2020Song H, Sun N, Lin L, Wei S, Zeng K, Liu W, Wang C, Zhong X, Wang M, Wang S, et al.anti‐Ki‐67 (sc‐15402, Santa Cruz Biotechnology), anti‐GAPDH (AC002, ABclonal Technology), anti‐FKBP5 (#12210S, Cell Signaling Technology), and anti‐trimethyl H3K36 (ABE435, Millipore). 2.2 Cell culture, siRNA

(20) Somatic Tissue Engineering in Mouse Models Reveals an Actionable Role for WNT Pathway Alterations in Prostate Cancer MetastasisCancer discoveryJuly 1, 2020Leibold J, Ruscetti M, Cao Z, Ho YJ, Baslan T, Zou M, Abida W, Feucht J, Han T, Barriga FM, et al.antibodies against Axin1 (2087), phospo-β-catenin S33/S37/T41 (9561), PTEN (9188), P53 (2524), and FKBP5 (12210) from Cell Signaling, AR (ab108341), cyclophilin B (ab16045), and NKX3.1 (ab196020) from Abcam, APC

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FKBP5 (D5G2) Rabbit mAb

FKBP5 (D5G2) Rabbit mAb from Cell Signaling Technology

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Cell Signaling Technology

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FKBP5 (D5G2) Rabbit mAb from Cell Signaling Technology

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