CaMKII-alpha (D10C11) Rabbit mAb 11945S from Cell Signaling Technology

Product Specs
ItemCaMKII-alpha (D10C11) Rabbit mAb
CompanyCell Signaling Technology
Price $339.00 Inquire
Catalog Number11945S
Quantity100 µl
ApplicationsW
ReactivityH, M, R
ClonalityMonoclonal
TargetCaMK2-alpha
HostRabbit
NCBI Full Gene Namecalcium/calmodulin dependent protein kinase II alpha
NCBI Gene AliasesCAMKA, CaMKIINalpha, CaMKIIalpha, MRD53, MRT63
ModificationsCaMK2-alpha (Tyr437) phosphate
Research AreaNeuroscience
IsotypeIgG
CloneD10C11
Molecular Weight50

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Cell Signaling Technology

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Danvers, Massachusetts 01923

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Phone: 877-616-CELL
Phone: 978-867-2388
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Website: http://www.cellsignal.com/

Website: Technical Support

(1) METTL3-mediated m6A modification of CACNA1E promotes osteosarcoma progression and chemoresistance by enhancing WNT7B-mediated Ca2+ signalingMolecular CancerJanuary 19, 2026Chaotao Chen, Kai Xiong, Feiyuan Liang, Yanping Zhong, Xiong Qin, Nanchang Huang, Yuqi Fang, Bo Zhu, Jianwen Cheng, Qingjun Wei, et al.(ab195352), WNT7B (ab227607), and P-gp (ab129450) from Abcam (Cambridge, MA, USA); CAMK2A antibody (#11945) from CST (Danvers, MA, USA); antibodies of CAMK2N (SAB4300530) and PLCB2 (HPA041298) from Sigma-Aldrich

(2) Calcium/calmodulin-dependent protein kinase II α and β differentially regulate mammalian sleepCommun BiolJanuary 5, 2025Weiwen Yang, Jingyi Shi, Chenggang Li, Jingqun Yang, Jianjun Yu, Juan Huang, Yi Raoinstructions. Antibodies used in this study included anti-β-actin antibody (ab213262, Abcam); anti-CaMKIIα (#11945, Cell Signaling), anti-CaMKIIβ anitibody (ab34703, Abcam); anti-phospho-CaMKII (Thr286) (#12716, Cell Signaling

(3) HDAC9‐mediated calmodulin deacetylation induces memory impairment in Alzheimer's diseaseCNS Neuroscience & TherapeuticsFebruary 7, 2024Hai‐Long Zhang, Shufen Hu, Pin Yang, Han‐Chun Long, Quan‐Hong Ma, Dong‐Min Yin, Guang‐Yin Xu(CaM) (Millipore, 05‐173), anti‐Acetylated‐Lysine (Cell Signaling, 9441), anti‐CaMKIIα (Cell Signaling, 11945), anti‐p‐CaMKIIα Thr286 (Sigma, SAB4300228), anti‐GluR1 (Abcam, ab109450), anti‐p‐GluR1 Ser831 (Abcam,

(4) Prenatal Cannabinoid Exposure Elicits Memory Deficits Associated with Reduced PSA-NCAM Expression, Altered Glutamatergic Signaling, and Adaptations in Hippocampal Synaptic PlasticityCellsOctober 26, 2023Priyanka D. Pinky, Jenna Bloemer, Warren D. Smith, Yifeng Du, Ryan T. Heslin, Sharay E. Setti, Jeremiah C. Pfitzer, Kawsar Chowdhury, Hao Hong, Subhrajit Bhattacharya, et al.Signaling Technology,75574,AB_2799873,1:1000 CaMKII,"Rabbit, monoclonal",H M R,Cell Signaling Technology,11945,AB_2797775,1:1000 Phospho-CaMKII,"Rabbit, monoclonal",H M R Dr,EMD Millipore,AB3865,AB_11212950,1:1000 Synaptophysin,"Rabbit,

(5) Using ΔK280 Tau(RD) Folding Reporter Cells to Screen TRKB Agonists as Alzheimer's Disease Treatment StrategyBiomoleculesJanuary 23, 2023Weng ZK, Lin TH, Chang KH, Chiu YJ, Lin CH, Tseng PH, Sun YC, Lin W, Lee-Chen GJ, Chen CM.CST), BCL2 (1:1000; #3033, BioVision), BDNF (1:1000; #ab108319, Abcam, Cambridge, UK), CaMKII (1:1000; #11945, CST), p-CaMKII T286 (1:1000; #12716, CST), CASP3 (1:1000; #9661, CST), CREB (1:500; #sc-186, Santa Cruz Biotechnology

(6) Proteomic-Based Approach Reveals the Involvement of Apolipoprotein A-I in Related Phenotypes of Autism Spectrum Disorder in the BTBR Mouse ModelInternational journal of molecular sciencesDecember 4, 2022Li Q, Shi Y, Li X, Yang Y, Zhang X, Xu L, Ma Z, Wang J, Fan L, Wu L.phospho-CaMKII (Thr286) (D21E4) (Cat. 12716s, RRID: AB_2713889, 1:1000, Cell Signaling), CaMKII-α (D10C11) (Cat. 11945s, RRID: AB_2797775, 1:1000, Cell Signaling), CREB (Cat. 9197s, RRID: AB_331277, 1:1000, Cell Signaling),

(7) Metabolic dyshomeostasis induced by SARS-CoV-2 structural proteins reveals immunological insights into viral olfactory interactionsFrontiers in ImmunologySeptember 8, 2022Mercedes Lachén-Montes et al.anti-phospho-MEK1/2 (S217/221) (ref. 9154), anti-phospho CAMKII (Y86) (ref.12716) and anti-CAMKII (ref.11945) were purchased from Cell Signaling Technology. Anti-PKC-pan was from Sigma Aldrich (ref. SAB4502356).

(8) Steroid Receptor Coactivator 3 Regulates Synaptic Plasticity and Hippocampus-dependent MemoryNeuroscience BulletinDecember 1, 2021Hai-Long Zhang, Bing Zhao, Pin Yang, Yin-Quan Du, Wei Han, Jianming Xu, Dong-Min YinCell Signaling); anti-Calmodulin (05-173, Millipore, Merck KGaA, Darmstadt, Germany); anti-CaMKIIα (11945, Cell Signaling); anti-phospho-CaMKIIα (pThr286) (SAB4300228, Sigma, Merck KGaA); anti-NR2A (04-901,

(9) Antenatal low-intensity pulsed ultrasound reduces neurobehavioral deficits and brain injury following dexamethasone-induced intrauterine growth restrictionBrain pathology (Zurich, Switzerland)November 1, 2021Hung TH, Liu YC, Wu CH, Chen CC, Chao H, Yang FY, Chen SF.GTX102643) from GeneTex (Irvine, CA, USA); anti‐pCaMKII (1:1000; #12716), anti‐total CaMKII (1:1000; #11945), anti‐pAkt S473 (1:1000; #9271), anti‐pAktT308 (1:1000; #4056), anti‐total Akt (1:1000; #9272), anti‐pERK

(10) SRC3 acetylates calmodulin in the mouse brain to regulate synaptic plasticity and fear learningThe Journal of biological chemistrySeptember 1, 2021Zhang HL, Han W, Du YQ, Zhao B, Yang P, Yin DM.Cell Signaling (9715); anti-Flag, Sigma (F7425); anti-CaM, Millipore (05-173); anti-CaMKIIα, Cell Signaling (11945); anti-p-CaMKIIα Thr286, Sigma (SAB4300228); anti-Acetyllysine, Cell Signaling (9441); anti-p-GluR1

(11) Acetylation of calmodulin regulates synaptic plasticity and fear learningThe Journal of biological chemistrySeptember 1, 2021Zhang HL, Zhao B, Han W, Sun YB, Yang P, Chen Y, Ni D, Zhang J, Yin DM.anti-Histone H3, Cell Signaling (9715); anti-Calmodulin, Millipore (05-173); anti-CaMKIIα, Cell Signaling (11945); anti-p-CaMKIIα Thr286, Sigma (SAB4300228); anti-Acetyllysine, Cell Signaling (9441); anti-p-GluR1

(12) Effects of N-Methyl-D-aspartate receptor (NMDAR) and Ca2+/ calmodulin-dependent protein kinase IIα (CaMKIIα) on learning and memory impairment in depressed rats with different charge by modified electroconvulsive shockAnnals of Translational MedicineAugust 1, 2021Yuxi Zhang, Li Ren, Su Min, Feng Lv, Jian YuCambridge, MA, USA), GluN2A (1:1,000, ab14596, Abcam), GluN2B (1:1,000, ab65783, Abcam), CaMKIIα (1:1,000, 11945S, Cell Signaling Technology, Danvers, MA, USA), p-T305-CaMKII (1:1,000, AF3492, Affinity, Cincinnati,

(13) Doxorubicin induces dysregulation of AMPA receptor and impairs hippocampal synaptic plasticity leading to learning and memory deficitsHeliyonJuly 1, 2021Alhowail AH, Pinky PD, Eggert M, Bloemer J, Woodie LN, Buabeid MA, Bhattacharya S, Jasper SL, Bhattacharya D, Dhanasekaran M, et al.,Cell Signaling Technology,13607,AB_2650557,"1:1,000" Anti-CaMKII,"Rabbit, monoclonal",H M R,Cell Signaling Technology,11945,AB_2797775,"1:1,000" Anti-phospho-CaMKII,"Rabbit, monoclonal",H M R Dr,EMD Millipore,AB3865,AB_11212950,"1:1,000" Anti-BDNF,"mouse,

(14) Structure of a GRK5-Calmodulin Complex Reveals Molecular Mechanism of GRK Activation and Substrate TargetingMolecular CellJanuary 1, 2021Konstantin E. Komolov et al.phospho-α-synuclein (Ser129) (1:1000, 01525191: Wako), pan CaMKII (1:1000, 3362S: Cell Signaling), CaMKIIα (1:3000, 11945: Cell Signaling), phospho-CaMKIIα (Thr286) (1:1000, 12716: Cell Signaling), α-tubulin (1:20000, T5168:

(15) Amyotrophic Lateral Sclerosis Is Accompanied by Protein Derangements in the Olfactory Bulb-Tract AxisInternational Journal of Molecular SciencesNovember 5, 2020Mercedes Lachén-Montes, Naroa Mendizuri, Karina Ausin, Pol Andrés-Benito, Isidro Ferrer, Joaquín Fernández-Irigoyen, Enrique Santamaría(Thr180/Tyr182) (ref. 4511), anti p38 MAPK (ref. 9212), anti-pCAMKII (Thr286) (ref. 12,716), anti-CAMKII (ref.11945), anti-pPDK1 (ser241) (ref. 3061), anti-PDK1 (ref. 3062) and anti-pPKC-pan (ref. 9379) were purchased

(16) Epilepsy in a melanocyte-lineage mTOR hyperactivation mouse model: A novel epilepsy modelPloS oneJanuary 1, 2020Yang F, Yang L, Wataya-Kaneda M, Teng L, Katayama I.cFOS (ab208942, Abcam, Cambridge, UK) at 1:200, Parvalbumin (SAB4200545, Sigma) at 1:100, CaMKII-α (#11945, Cell Signaling Technology) at 1:100, COXIV (#459600, Invitrogen) at 1:200, GFAP (#12389, Cell Signaling Technology

(17) Regulation of intracellular Ca2+/CaMKII signaling by TRPV4 membrane translocation during osteoblastic differentiationBiophysics ReportsDecember 1, 2019Fen Hu, Yali Zhao, Zhenhai Hui, Fulin Xing, Jianyu Yang, Imshik Lee, Xinzheng Zhang, Leiting Pan, Jingjun Xuanti-TRPV4 (1:200, ACC-034, Alomone labs, Israel), anti-CaMKII and anti-phosphorylated CaMKII (1:1000, 11945S and 12716S, Cell Signaling Technology, USA), as well as mouse anti-b-actin (1:20,000, 60,008-1-lg, Proteintech, USA)

(18) Ethanol Exposure Impairs AMPK Signaling and Phagocytosis in Human Alveolar Macrophages: Role of Ethanol MetabolismAlcoholism, clinical and experimental researchAugust 1, 2019Kaphalia L, Srinivasan MP, Kakumanu RD, Kaphalia BS, Calhoun WJ.kinase (AMPK) α (62 kDa; Cat# 2535), Ca2+/calmodulin-dependent protein kinase (CaMKK) β (50 kDa; Cat# 11945), liver kinase β (LKB) 1 (54 kDa; Cat# 3047) or acetyl CoA carboxylase (ACC)1 (280 kDa; Cat # 3676)

(19) Blockade of MCU-Mediated Ca²⁺ Uptake Perturbs Lipid Metabolism via PP4-Dependent AMPK DephosphorylationCell reportsMarch 26, 2019Tomar D, Jaña F, Dong Z, Quinn WJ 3rd, Jadiya P, Breves SL, Daw CC, Srikantan S, Shanmughapriya S, Nemani N, et al.ATP5A,Abeam,Cat# ab14748 Rabbit monoclonal anti- CaMKII-α (D10C11),Cell Signaling Technology,Cat# 11945 Rabbit Polyclonal anti- Carnitine Palmitoyl Transferase-1,Alpha Diagnostic Intl. Inc.,Cat# CPT1M11-A Mouse

(20) SK Channel Modulates Synaptic Plasticity by Tuning CaMKIIα/β DynamicsFrontiers in synaptic neuroscienceJanuary 1, 2019Shrestha A, Sultana R, Lee CC, Ogundele OM.lysates. Here, we used the following primary antibodies—Rabbit anti CaMKIIα Antibody (Cell Signaling #11945S), Rabbit anti Phospho-CaMKIIα/β:T286/T287 (Cell Signaling #12716), Rabbit anti phospho-CaMKII T305/306

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CaMKII-alpha (D10C11) Rabbit mAb

CaMKII-alpha (D10C11) Rabbit mAb from Cell Signaling Technology

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Cell Signaling Technology

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CaMKII-alpha (D10C11) Rabbit mAb from Cell Signaling Technology

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