PI3 Kinase p55 (D2B3) Rabbit mAb 11889S from Cell Signaling Technology

Product Specs
ItemPI3 Kinase p55 (D2B3) Rabbit mAb
CompanyCell Signaling Technology
Price $339.00 Inquire
Catalog Number11889S
Quantity100 µl
ApplicationsW, IP
ReactivityH, M
ClonalityMonoclonal
TargetPI3K p55
HostRabbit
NCBI Full Gene Namephosphoinositide-3-kinase regulatory subunit 3
NCBI Gene Aliasesp55, p55-GAMMA, p55PIK
Research AreaPI3K / Akt Signaling
IsotypeIgG
CloneD2B3
Molecular Weight55

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Cell Signaling Technology

3 Trask Lane

Danvers, Massachusetts 01923

United States

Phone: 877-616-CELL
Phone: 978-867-2388
Fax: 866-432-6112
Fax: 978-867-2488

Company Profile

Website: http://www.cellsignal.com/

Website: Technical Support

(1) KIN17 facilitates the initiation and progression of renal tumor progression through the PI3K-AKT-mTOR pathwayScientific ReportsJanuary 19, 2026Yibo Wen, Lei Lyu, He Zhang, Yanping Zhang, Shuai Yang, Qingwei Wang, Yue Song, Jianguo Wen60203–2-Ig, 1:10,000), mTOR (Proteintech, Catalog number: 66888–1-Ig, 1:10,000), PI3K(CST, Catalog number: 11889, 1:1000), p-AKT(CST, Catalog number: 4060S, 1:2000), p-mTOR(CST, Catalog number: 5536S, 1:1000), p-PI3K(CST,

(2) Adenovirus E4ORF1 activates isoform-specific phosphatidylinositol 3-kinase signaling in human endothelial cellsJournal of Biological ChemistryNovember 13, 2025Fuqiang Geng, Mariko Kobayashi, Yang Lin, Jesus Maria Gomez-Salinero, Dominick Romano, Jean Kanyo, Jennifer Geng, Ying Liu, Michael Ginsberg, Jae-Hung Shieh, et al.ab191606, rabbit), p85β (Abcam ab180967, rabbit); p55γ (Proteintech Group 27035-1-P; Cell Signaling 11889; both rabbit); Rab7 (Cell Signaling 95,746, mouse); EEA1 (Cell Signaling 48453, mouse); Paxillin (BD Biosciences

(3) miR‑100‑5p and miR‑203a‑3p suppress esophageal squamous cell carcinoma progression by targeting FKBP5Oncol RepOctober 3, 2025Hiroto Tanaka, Suguru Maruyama, Katsutoshi Shoda, Yoshihiko Kawaguchi, Yudai Higuchi, Takaomi Ozawa, Takashi Nakayama, Ryo Saito, Wataru Izumo, Koichi Takiguchi, et al.phosphorylated (p-)PI3K (1:1,000; cat. no. 17366; Cell Signaling Technology, Inc.), PI3K (1:1,000; cat. no. 11889; Cell Signaling Technology, Inc.), p-AKT (1:1,000; cat. no. 4060; Cell Signaling Technology, Inc.),

(4) BACE1 Inhibition Protects Against Type 2 Diabetes Mellitus by Restoring Insulin Receptor in MiceInternational Journal of Molecular SciencesMay 26, 2025Tingting Lin, Ting Liang, Yong Shen, Feng GaoUSA), rabbit anti-phosphor-AKT (9271, Cell signaling technology, Danvers, MA, USA), rabbit anti-PI3K (11889S, Cell signaling technology, Danvers, MA, USA), rabbit anti-phosphor-PI3K (4228S, Cell signaling technology,

(5) STEAP3 promotes triple-negative breast cancer growth through the FGFR1-mediated activation of PI3K/AKT/mTOR signalingiScienceApril 24, 2025Lifang Yuan, Yuhan Bao, Junbao Liu, Ping SunAB_10913811 STEAP3 (IHC),Bioss USA,Cat# bs-12825R; RRID: AB_3675913 PI3K(P55),Cell Signaling Technology,Cat# 11889S; RRID: AB_2797756 p-PI3K(Tyr199),Cell Signaling Technology,Cat# 4228T RRID: AB_659940 AKT,Abcam,Cat#

(6) Proteomics uncovers ICAM2 (CD102) as a novel serum biomarker of proliferative lupus nephritisLupus Sci MedApril 23, 2025Zhengyong Li, Yifang Sun, Yixue Wang, Fengxun Liu, Shaokang Pan, Songwei Li, Zuishuang Guo, Dan Gao, Jinghua Yang, Zhangsuo Liu, et al.(10121-2-AP, Proteintech), anti-VCAM1 (ab134047, Abcam), Akt (75692T, CST), p-Akt (9018T, CST), PI3K (11889s, CST) and p-PI3K (11889s, CST) overnight at 4°C. Then the membranes were incubated with secondary antibodies

(7) Tudor-SN exacerbates pathological vascular remodeling by promoting the polyubiquitination of PTEN via NEDD4-1Journal of Biomedical ScienceSeptember 5, 2024Yichen Wu, Zilong Chen, Zhe Zheng, Xiaoguang Li, Jiangcheng Shu, Ruiqi Mao, Jie An, Siyuan Fan, Ruijie Luo, Yi Guo, et al.1:1000 dilution), AKT (CST, #4691, 1:1000 dilution), p-P13K (CST, #17366, 1:1000 dilution), PI3K (CST, #11889), PTEN (Abclonal, A19104, 1:1000 dilution), P53 (Abclonal, A0263, 1:1000 dilution), CREBBP (Abclonal,

(8) Von Hippel Lindau tumor suppressor controls m6A-dependent gene expression in renal tumorigenesisThe Journal of clinical investigationApril 15, 2024Zhang C, Yu M, Hepperla AJ, Zhang Z, Raj R, Zhong H, Zhou J, Hu L, Fang J, Liu H, et al.manufacture’s instruction. IHC. Rabbit polyclonal antibody against PIK3R3 (Cell Signaling Technology, 11889S) or Phospho-AKT (Thr308) PIK3R3 (Cell Signaling Technology, 9275S) were used for IHC staining. The IHC

(9) Functional high-throughput screen identifies microRNAs that promote butyrate-induced death in colorectal cancer cellsMolecular therapy. Nucleic acidsDecember 13, 2022Ali SR, Humphreys KJ, Simpson KJ, McKinnon RA, Meech R, Michael MZ.Antibody #3218, eEF2k Antibody #3692, Met (D1C2) XP Rabbit mAb #8198, PI3 Kinase p55 (D2B3) Rabbit mAb #11889 (Cell Signaling Technology), NUP62 Antibody ab140651 (Abcam), TRIM29 Antibody GTX115749 (Genetex, CA,

(10) Vespakinin-M, a natural peptide from Vespa magnifica, promotes functional recovery in stroke miceCommunications biologyJanuary 20, 2022Zhao H, Wang M, Gao Y, Wu X, Xiao H, Yang D, He F, Lv J, Xie, Wang Q, et al.(L35A5) Mouse mAb (1:1000, 4814S, CST), phospho-IκBα (Ser32) (1:1000,2859S, CST), PI3 kinase p85α (1:1000,11889S, CST), and phospho-PI3 kinase p85 (Tyr458)/p55 (Tyr199) (1:1000, 17366S, CST). Transmission electron microscopy

(11) Lnc-ORA interacts with microRNA-532-3p and IGF2BP2 to inhibit skeletal muscle myogenesisThe Journal of biological chemistryJanuary 1, 2021Cai R, Zhang Q, Wang Y, Yong W, Zhao R, Pang W.Novus Biologicals), AKT (1:1000; no. 9272S; CST), p-AKT (Ser473) (1:2000; no. 4060S; CST), PI3K (p55α) (1:1000; no. 11889S; CST), p-PI3K p55 (Tyr199) (1:1000; no. 4228S; CST), β-tubulin (1:200; no. sc-58880; Santa Cruz Biotechnology),

(12) RON signalling promotes therapeutic resistance in ESR1 mutant breast cancerBritish journal of cancerJanuary 1, 2021Dustin D, Gu G, Beyer AR, Herzog SK, Edwards DG, Lin H, Gonzalez TL, Grimm SL, Coarfa C, Chan DW, et al.(cat# 4060S), AKT (cat# 9272S), p-p44/42 (cat# 4370S), p44/42 (cat# 4695S), p85 (cat# 4257S), p55 (cat# 11889S) were purchased from Cell Signaling Technologies, Danvers, MA. GAPDH (cat# sc-25778) was purchased from

(13) PIK3R3 inhibits cell senescence through p53/p21 signalingCell death & diseaseSeptember 24, 2020Chen Q, Sun X, Luo X, Wang J, Hu J, Feng Y.Eagle’s medium including 10% fetal bovine serum. Antibodies and reagents The antibody to PIK3R3 (#11889) and HP1α (#2616) were purchased from Cell Signaling Technology Company (MA, USA). Antibodies to p53

(14) Entamoeba histolytica stimulates the alarmin molecule HMGB1 from macrophages to amplify innate host defensesMucosal immunologyMarch 1, 2020Begum S, Moreau F, Leon Coria A, Chadee K.anti-HMGB1 (ab18256), anti-phospho-PI3K (Cell Signaling, 4228), total anti-PI3K p55 (Cell Signaling, 11889), anti-phospho-IκB (Cell Signaling, 9246), total anti-IκB (Cell Signaling, 4812), and antiGAPDH (Millipore,

(15) Synaptotagmin 12 (SYT12) Gene Expression Promotes Cell Proliferation and Progression of Lung Adenocarcinoma and Involves the Phosphoinositide 3-Kinase (PI3K)/AKT/Mammalian Target of Rapamycin (mTOR) PathwayMedical science monitor : international medical journal of experimental and clinical researchFebruary 28, 2020Liu K, Luo J, Shao C, Ren Z, Sun S, Zhu Y, Zhou H, Jiang Z, Li X, Gu W, et al.were to SYT12 (1: 1,000) (Cat. No. TA342629; Origene, Rockville, MD, USA), PIK3R3 (1: 1,000) (Cat. No. 11889; Cell Signaling Technology, Danvers, MA, USA), phospho-PIK3R3 (1: 1,000) (Cat. No. 4228; Cell Signaling Technology,

(16) Facilitating Granule Cell Survival and Maturation in Dentate Gyrus With Baicalin for Antidepressant TherapeuticsFrontiers in pharmacologyJanuary 1, 2020Zhao F, Tao W, Shang Z, Zhang W, Ruan J, Zhang C, Zhou L, Aiello H, Lai H, Qu R.membrane was incubated with a primary antibody at 4°C overnight. Primary antibodies include PI3K (1:1,000, 11889, Cell Signaling), Phospho-PI3K (1:1000,4228, Cell Signaling), AKT (1:500, 10176-2-A, Proteintech), Phospho-AKT

(17) Transfection with GLS2 Glutaminase (GAB) Sensitizes Human Glioblastoma Cell Lines to Oxidative Stress by a Common Mechanism Involving Suppression of the PI3K/AKT PathwayCancersJanuary 19, 2019Majewska E, Márquez J, Albrecht J, Szeliga M.PDK1 (#17086-1-AP, ProteinTech, Chicago, IL, USA), p-PI3K (Tyr199) (#4228, Cell signaling), PI3K (#11889, Cell Signaling), p-NF-κB (Ser536) (#MAB72261, Novus Biologicals, Littleton, CO, USA), and NF-κB (#4764,

(18) New Molecular Mechanism Underlying Myc-Mediated Cytochrome P450 2E1 Upregulation in Apoptosis and Energy Metabolism in the MyocardiumJournal of the American Heart AssociationJanuary 8, 2019Guan F, Yang X, Li J, Dong W, Zhang X, Liu N, Gao S, Wang J, Zhang L, Lu D.phosphor‐PI3 Kinase p85 (Tyr458)/p55 (Tyr199) (Cell Signaling; 4228, 1:1000), PI3 Kinase p85 (Cell Signaling; 11889, 1:1000), phosphor‐Akt (Ser473) (Cell Signaling; 4060, 1:2000), Akt (Cell Signaling; 8596, 1:1000),

(19) Naturally existing isoforms of miR-222 have distinct functionsNucleic Acids ResearchNovember 2, 2017Feng Yu, Katherine A. Pillman, Corine T. Neilsen, John Toubia, David M. Lawrence, Anna Tsykin, Michael P. Gantier, David F. Callen, Gregory J. Goodall, Cameron P. Brackenat 1:1000 - p53 (Santa Cruz sc-126), p21waf1/cip1 (Cell Signalling Technology #2947), PI3K p55 (CST #11889), phospo-Akt (CST #4051), Akt (CST #9272), PARP (CST #9542) and Casp3 (CST #9662). Puma (ProSci #41232)

(20) TMEM74 promotes tumor cell survival by inducing autophagy via interactions with ATG16L1 and ATG9ACell death & diseaseAugust 31, 2017Sun Y, Chen Y, Zhang J, Cao L, He M, Liu X, Zhao N, Yin A, Huang H, Wang L.5114); anti-p-AKT (CST,4051S); anti-AKT (CST, 4691S); anti-p-PI3K(CST, 4228P); anti-PI3K p55 (CST, 11889S); anti-p-p70S6K (CST,9234S); anti-p70S6K (CST, 2708S); anti-p-mTOR (CST, 2971S); anti-mTOR (CST,2983S);

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PI3 Kinase p55 (D2B3) Rabbit mAb

PI3 Kinase p55 (D2B3) Rabbit mAb from Cell Signaling Technology

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Cell Signaling Technology

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PI3 Kinase p55 (D2B3) Rabbit mAb from Cell Signaling Technology

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