Bak (D4E4) Rabbit mAb 12105S from Cell Signaling Technology

Product Specs
ItemBak (D4E4) Rabbit mAb
CompanyCell Signaling Technology
Price $339.00 Inquire
Catalog Number12105S
Quantity100 µl
ApplicationsW, IP, IHC-P, IF-IC, FC-FP
ReactivityH, M, R, Mk
ClonalityMonoclonal
TargetBak1
HostRabbit
NCBI Full Gene NameBCL2 antagonist/killer 1
NCBI Gene AliasesBAK, BAK-LIKE, BCL2L7, CDN1
Research AreaApoptosis
IsotypeIgG
CloneD4E4
Molecular Weight25

Add to Compare List

Cell Signaling Technology

3 Trask Lane

Danvers, Massachusetts 01923

United States

Phone: 877-616-CELL
Phone: 978-867-2388
Fax: 866-432-6112
Fax: 978-867-2488

Company Profile

Website: http://www.cellsignal.com/

Website: Technical Support

(1) mRNA lipid-nanoparticle-mediated mitochondrial apoptosis augments adoptive T cell immunotherapyCell Reports MedicineApril 21, 2026Jiayan Fu, Yaoqi Liu, Zhenyu Zhong, Benyuan Cao, Luna Ran, Zijia Guo, Haiyang Dong, Nengcheng Bao, Rongqing Pan, Jinqiang Wang, et al.antibody,Cell Signaling Technology,Cat#2772; RRID:AB_10695870 Bak antibody,Cell Signaling Technology,Cat#12105; RRID:AB_2716685 Bcl-2 (D17C4) Rabbit mAb,Cell Signaling Technology,Cat#3498; RRID:AB_1903907 Puma (E2P7G) Rabbit mAb

(2) Synaptojanin-2-binding protein ameliorates oxidative stress, neuroinflammation and depression-like behaviors via SYNJ2/PIP2/IP3 signaling pathwayRedox BiolApril 7, 2026Wenjing Wang, Xiao Chen, Ye Li, Changmin Wang, Mengni Chang, Ruojing Guo, Penghui Wei, Zhipeng Xu, Shuyan Yu9252; Cell Signaling Technology), anti-BAX (1:1000; 2772; Cell Signaling Technology), anti-BAK (1:1000; 12105; Cell Signaling Technology), anti-IL-1β (1:100; sc-12742; Santa Cruz). After three washes with TBST

(3) Carnosic Acid Activates the STING/IRF3 Pathway to Induce Nitric Oxide-Mediated Apoptosis in Osteosarcoma CellsAntioxidants (Basel)March 16, 2026Weixiong Guo, Lanlan Yin, Qiang Wu, Jiaqi Chuanti-PARP (CST, Cat# 9542), anti-Bax (CST, Cat# 5023), anti-Bcl-2 (CST, Cat# 3498), anti-Bak (CST, Cat# 12105), anti-Bcl-xL (CST, Cat# 2764), and anti-α-Tubulin (CST, Cat# 2148). Alexa Fluor 488- or 594-conjugated

(4) The human antibacterial factor APOL3 couples lysosomal damage to mitochondrial DNA efflux and type I IFN inductionMol CellFebruary 24, 2026Dominic A. Ritacco, Hamna Shahnawaz, Antonia Oduguwa, Jacob Hawk, Brianna Vizcaino, Donna L. Farber, Ryan G. GaudetRESOURCE,SOURCE,IDENTIFIER Antibodies,Antibodies,Antibodies Rabbit anti-BAX,Cell Signaling,411162 Rabbit anti-BAK,Cell Signaling,12105 Rabbit anti-APOL3,Abcam,Ab154869 Rabbit anti-GAPDH,Abcam,Ab9485 Rabbit anti-β-Actin,Cell Signaling,4970 Rabbit

(5) Shear stress-induced Ca2+ influx triggers endoplasmic reticulum stress and cardiomyocyte apoptosis: implications for mitral regulationBiological ResearchFebruary 8, 2026Wei-Ting Chang, Jun-Ming Su, Fan-E Mo, Jhih-Yuan Shih, Wen-Tai Chiusc390063), CHOP (Cell Signaling, 2895), Bax (Genetex, GTX109683), Bcl-2 (BD, 610538), Bak (Cell Signaling, 12105), caspase 9 (Santa Cruz, sc56076), caspase 12 (Cell Signaling, 35965), caspase 3 (Abcam, ab32042), caspase

(6) SOX21 suppresses glioblastoma growth by repressing AP-1 activityCell Death DisJanuary 31, 2026Eltjona Rrapaj, Juan Yuan, Idha Kurtsdotter, Vsevolod Misyurin, Guido Alessandro Baselli, Johan Holmberg, Oscar Persson, Maria Bergsland, Jonas MuhrH3K4me1 (Diagenode, C15410194). BIM (Cell Signaling Technology, #2933), BAK (Cell Signaling Technology, #12105), BAX (Cell Signaling Technology, #2772), CASPASE3 (Cell Signaling Technology, #9665), cleaved CASPASE3

(7) Stc1-expressing myofibroblasts are a developmentally distinct lineage cleared through apoptosis in the neonatal lungCell ReportsJanuary 27, 2026Melinda E. Snitow, Sylvia N. Michki, Fatima N. Chaudhry, Youbin Park, Rachna Dherwani, Jeremy B. Katzen, David B. Frank, Jarod A. Zepp,Cell Signaling Technologies,Cat# 14796; RRID:AB_2716251 Rabbit Monoclonal Anti-Bak (D4E4),Cell Signaling Technology,"Cat# 12105, RRID:AB_2716685" Goat Polyclonal Anti-Human/Mouse EBF-1 Antibody,R&D Systems,Cat# AF5165; RRID: AB_2097398 Rabbit

(8) Synaptotagmin-7 drives stress-induced cardiomyocyte necroptosis via the p53-Bak-mPTP axisTheranosticsJanuary 1, 2026Jialei Li, Shuang Wang, Yu Han, Jinhong Liu, Yuhan Li, Jingyu Zhang, Liping Guo, Yue Jin, Jiasong Chang, Ting Liu, et al.105173), anti-p53 (CST, USA, #32532S), anti-Histone (Beyotime, China, AF0009), anti-Bak (CST, USA, #12105), anti-Cleaved Caspase 3 (CST, USA, #9664), anti-Cleaved Caspase 9 (CST, USA, #52873), anti-Cleaved

(9) Mitochondrial DNA release via mPTP and BAX/BAK drives inflammatory injury in intestinal ischemia reperfusionCell Communication and SignalingDecember 24, 2025Yixin Jing, Yiguo Zhang, Tulanisa Kadier, Ke Ding, Rong Chen, Qingtao Mengfollows: anti-BAX (1:10000, Proteintech, 50599-2-Ig, China), anti-BAK (1:1000, Cell Signaling Technology, 12105, USA), anti-MCU (1:1000, Cell Signaling Technology, 14997 S, USA), anti-Occludin (1:1000, Cell Signaling Technology

(10) Developing therapeutic strategies to target MCL1 and BCLXL in lethal prostate canceriScienceDecember 19, 2025Daniel Westaby, Juan M. Jiménez-Vacas, Ines Figueiredo, Jonathan Welti, Bora Gurel, Denisa Bogdan, Lorenzo Buroni, Antje J. Neeb, Jan Rekowski, Ana Padilha, et al.RRID:AB_2228008 BAX,Cell Signaling Technology,5023: RRID:AB_10557411 BAK,Cell Signaling Technology,12105; RRID:AB_2716685 PARP,Cell Signaling Technology,9542; RRID:AB_2160739 Cleaved caspase 3,Cell Signaling Technology

(11) Loss of Lipin1 Contributes to Multiple Pathological Processes in the Development of Heart FailureJournal of the American Heart AssociationDecember 16, 2025John Karanja Kamau, Anthony Milard Young, Clintoria R. Williams, Eric S. Bennett, Andrew R. Ednie, Hongmei Ren597, Santa Cruz Biotechnology Inc.), BAX (#2772, CST), CD68 (#97778, CST), CD206 (#24595, CST), BAK (#12105, CST), RIPK1 (receptor‐interacting serine/threonine‐protein kinase; #3493, CST), RIPK3 (#95702, CST),

(12) Innate immune and metabolic signals induce mitochondria-dependent membrane lysis via mitoxyperiosisCellDecember 11, 2025Yaqiu Wang, Jianlin Lu, Alexandre F. Carisey, Sangappa B. Chadchan, Ha Won Lee, R.K. Subbarao Malireddi, Bhesh Raj Sharma, Nagakannan Pandian, Rebecca E. Tweedell, Gustavo Palacios, et al.CST, 1:1000), MyD88 (4283, CST, 1:1000), TNF-R1 (13377, CST, 1:1000), BAX (2772, CST, 1:1000), BAK1 (12105, CST, 1:1000), BID (2003, CST, 1:1000), phospho-IκBα (Ser32, 2859, CST, 1:1000), IκBα (9242, CST, 1:1000),

(13) Current Advances in Anticancer Properties of Heptamethine Carbocyanine DZ‐1 Conjugated to Artesunate: Generation of Reactive Oxygen SpeciesJournal of Cellular BiochemistryDecember 10, 2025Badrinath Narayanasamy, Sarah Helmueller, Yi Zhang, Yong J. Leeanti-PARP-1 (Cat# 9532), anti-caspase-8 (Cat# 9746), anti-cleaved caspase-9 (Cat# 7237), anti-Bak (Cat #12105), anti-Bax (Cat# 2772), and anti-ATF-4 (Cat# 11815) were obtained from Cell Signaling Technology. Anti-β-actin

(14) DZ-1-Artesunate Induces Apoptosis Via a Bid-, Bax-, and Bak-Independent Caspase-3 Activation PathwayJ Oncol Res TherDecember 1, 2025Badrinath Narayanasamy, Sarah Helmueller, Yi Zhang, Alexandra Gangi, Heuiran Lee, Cheryn Song, Ha-Na Woo, Yong J. Lee(Mouse mAb; Cat#9668S), anti-cleaved caspase-3 (Rabbit mAb; Cat# 9664S), anti-Bak (Rabbit mAb; Cat #12105S), anti-Bax (Rabbit pAb; Cat #2772S), anti-Bid (Rabbit pAb; Cat#2002S), anti-cathepsin B (Rabbit mAb;

(15) Human umbilical cord mesenchymal stromal cell-derived exosomes alleviate antibiotic-induced intestinal barrier damage by regulating autophagy via the S100G/mTOR signaling pathwayCellular & Molecular Biology LettersNovember 17, 2025Yanji Guo, Yanpeng Li, Meng Shi, Yong Li, Jiayin Qiang, Jing Li, Hongyi Gao, Guoqiang Zhu, Bo Xie, Xiangjie Guo, et al.Boster), mTOR (1:1000, 2983, CST), P62 (1:2000, A7758, ABclonal), LC3 (1:1000, 12741 T, CST), Bak (1:1000, 12105, CST), Bax (1:1000, 2774, CST), GAPDH (1:5000, BM3874, Boster), and β-Actin (1:1000, AC026, ABclonal)

(16) Secondary Necrosis Following Caspase‐Activation can Occur Independently of Gasdermin EAdvanced ScienceNovember 4, 2025Shubhangi Gavali, Francesca Maremonti, Wulf Tonnus, Florian Gembardt, Marlena Nastassja Schlecht, Karolin Flade, Anne von Mässenhausen, Stephen W. G. Tait, Stefan R. Bornstein, Andreas Linkermannantibody,Abcam,ab202068 Anti‐MCL1 antibody,Abcam,ab32087 Anti‐BAX antibody,Cell Signaling,2772 Anti‐BAK antibody,Cell Signaling,12105 Anti‐GSDMD antibody,Cell Signaling,97558 Anti‐β‐actin antibody,Cell Signaling,3700S Anti‐mouse IgG; HRP‐linked

(17) Ro 31‐8220 suppresses bladder cancer progression via enhancing autophagy in vitro and in vivoFEBS Open BioNovember 1, 2025Shengjun Fu, Yan Tao, Shan Wu, Yuwen Gong, Youli Zhao, Shaomin Niu, Hui Cheng, You Mu, Na Xu, Ying Wang, et al.purchased from Abclonal (Wuhan, China). PARP (9532, Rabbit mAb), Bcl‐2 (2872, Rabbit mAb) and BAK (12105, Rabbit mAb) were purchased from Cell Signaling Technology (Danvers, MA, USA). Cell culture Human

(18) A microRNA CRISPR screen reveals microRNA-483-3p as an apoptotic regulator in prostate cancer cellsCell Death DisOctober 24, 2025Jonathan Tak-Sum Chow, Ayeisha Desjardins, Daniel K. C. Lee, Iulia A. Grigore, Linda Lee, Norman J. Fu, Stephanie Chau, Byeong Yeop Lee, Martino Marco Gabra, Leonardo SalmenaInvitrogen, PA5-55686), β-actin (1:10,000; CST, 4967), PUMA (1:1000; CST 12450T), BAK1 (1:1000; CST, 12105S), BAX (1:1000; CST, 5023T), IGF2 (1:1000; Invitrogen, MA5-17096). All uncropped original blots can be

(19) Subtype-specific divergent roles of calpain-1 and calpain-2 in basal A triple-negative breast cancerBMC Mol Cell BiolOctober 16, 2025Göklem Üner, Erdal Bedir, Petek Ballar Kirmizibayrakcaspase 3 (Cell Signaling-9661, UK), anti-PARP-1 (Cell Signaling-9532, UK), anti-BAK (Cell Signaling-12105, UK), and anti-Bcl-2 (Cell Signaling-15071, UK) and GAPDH (Cell Signaling-5174, UK). Densitometric analyses

(20) Atypical contribution of caspase-3 to melanoma cancer cell motility by regulation of coronin 1B activityCell Death DisOctober 6, 2025Kevin Berthenet, Serena Diazzi, Catherine Jamard, Kinga B. Stopa, Clara Gil, Stefan Dragan, Deborah Fanfone, Trang TM. Nguyen, Nathalie Al, Francois Virard, et al.TP401), Myc-tag (Thermo Fisher Scientific, 13-2500), BAX (Cell Signaling, 2772S), BAK (Cell Signaling, 12105S), P-PKCα (Invitrogen, 44-962G), PKCα (Cell Signaling, 2056T), ARP2/ARP3 (Bioss Antibodies, bs-12524R),

Be the First to Write a Review!

Bak (D4E4) Rabbit mAb

Bak (D4E4) Rabbit mAb from Cell Signaling Technology

Description

Cell Signaling Technology

Citations (217)

Reviews

Bak (D4E4) Rabbit mAb from Cell Signaling Technology

About Biocompare

Advertise with Us

Specialized Search Tools

Site Map