The Anti-FADD antibody from MyBioSource.com is a Rabbit Polyclonal antibody to FADD. This antibody recognizes Human antigen. The Anti-FADD antibody has been shown to work in the following applications: Western Blot.
Description
Description: Rabbit IgG polyclonal antibody for Protein FADD(FADD) detection. Tested with WB in Human.
Background: FADD, Fas-Associated protein with Death Domain, is a universal adaptor protein in apoptosis that mediates signaling of all known death domain-containing members of the TNF receptor superfamily. The FADD gene contains 2 exons and spans approximately 3.6 kb. By analysis of somatic cell hybrid panels and by fluorescence in situ hybridization, the FADD gene is mapped to 11q13.3. The protein encoded by this gene is an adaptor molecule that interacts with various cell surface receptors and mediates cell apoptotic signals. Through its C-terminal death domain, this protein can be recruited by TNFRSF6/Fas-receptor, tumor necrosis factor receptor, TNFRSF25, and TNFSF10/TRAIL-receptor, thus, it participates in the death signaling initiated by these receptors