The Anti-Cullin1 antibody from MyBioSource.com is a Rabbit Polyclonal antibody to CUL1, and Cullin 1. This antibody recognizes Human, Mouse, and Rat antigen. The Anti-Cullin1 antibody has been shown to work in the following applications: Immunohistochemistry, Immunohistochemistry - fixed, and Western Blot.
Description
Description: Rabbit IgG polyclonal antibody for Cullin-1(Cul1) detection. Tested with WB, IHC-P in Human, Mouse, Rat.
Background: Cullin 1, also known as CUL1, is a human protein and gene from cullin family. This protein plays an important role in protein degradation and protein ubiquitination. This is an essential component of the SCF(SKP1-CUL1-F-box protein) E3 ubiquitin ligase complex, which mediates the ubiquitination of proteins involved in cell cycle progression, signal transduction and transcription. Human cullin 1, but not the other closely related cullins 2, 3, 4A, and 5, selectively interacts with human SKP1