The Anti-survivin antibody from MyBioSource.com is a Rabbit Polyclonal antibody to BIRC5, and Survivin. This antibody recognizes Human antigen. The Anti-survivin antibody has been shown to work in the following applications: Western Blot.
Description
Description: Rabbit IgG polyclonal antibody for Baculoviral IAP repeat-containing protein 5(BIRC5) detection. Tested with WB in Human.
Background: Survivin, also called baculoviral inhibitor of apoptosis repeat-containing 5 or BIRC5, is a protein that, in humans, is encoded by the BIRC5 gene. Survivin is a member of the inhibitor of apoptosis(IAP) family. The survivin gene contains 4 exons. The survivin gene is mapped to chromosome 17q25 by pulsed field gel electrophoresis and single- and 2-color FISH. The survivin protein functions to inhibit caspase activation, thereby leading to negative regulation of apoptosis or programmed cell death. The survivin protein is expressed highly in most human tumours and fetal tissue, but is completely absent in terminally differentiated cells