The Mouse Anti Human Cellular Retinoic Acid binding Protein 2 Antibody from MyBioSource.com is a Mouse Monoclonal antibody to CRABP2. This antibody recognizes Human antigen. The Mouse Anti Human Cellular Retinoic Acid binding Protein 2 Antibody has been shown to work in the following applications: ELISA, and Western Blot.
Description
Introduction: CRABP2 NCBI Accession No: NP_001869 regulates the access of retinoic acid to the nuclear retinoic acid receptors. CRABP2 is involved in a regulatory feedback mechanism that controls the action of retinoic acid on cell differentiation. CRABP2 is involved in the conversion of vitamin A into its intracellular active form retinoic acid, which regulate the genes responsible for lipid metabolism and adipocyte differentiation. CRABP2 gene is located on chromosome 1q21-23 and this region has been linked with related disorders such as familial combined hyperlipidemia (FCHL) and type 2 diabetes mellitus. CRABP proteins are of low molecular weight having an important function in retinoic acid-mediated regulation of human skin growth and differentiation