MyBioSource.com's Mouse Anti Human Caspase-2 Antibody is a Mouse monoclonal antibody. The Mouse Anti Human Caspase-2 Antibody was generated using ICH1, and NEDD2 as the antigen. It reacts with Human. This antibody has been shown to work in applications such as: ELISA, and Western Blot.
Description
Introduction: Caspase-2 is a protein which belongs to the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases has a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. The proteolytic cleavage of Caspase-2 is induced by a variety of apoptotic stimuli