MyBioSource.com's Anti-Dopamine Receptor D3 antibody is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: Immunohistochemistry, Immunohistochemistry - fixed, and Western Blot. The Anti-Dopamine Receptor D3 antibody was generated using D3DR, Dopamine D3 Receptor, dopamine receptor D3, and DRD3 as the antigen and it reacts with Human, Mouse, and Rat.
Description
Description: Rabbit IgG polyclonal antibody for D(3) dopamine receptor(DRD3) detection. Tested with WB, IHC-P in Human, Mouse, Rat.
Background: DRD3 is a dopamine receptor that differs in its pharmacology and signaling system from the D1 and D2 receptors and represents both an autoreceptor and a postsynaptic receptor. DRD3 is localized to limbic areas of the brain, which are associated with cognitive, emotional, and endocrine functions. The DRD3 gene, which is mapped to chromosome 3, is like the DRD2 gene but unlike most other members of this superfamily and it contains introns, 5 in number. The position of 2 of the introns corresponds to that of introns in DRD2. The D3 receptor appeared to mediate some of the effects of antipsychotic drugs and drugs used in the treatment of Parkinson disease, which were previously though to interact only with D2 receptors