The Anti-ABCB6 antibody from MyBioSource.com is a Rabbit Polyclonal antibody to ABC, and ABCB6. This antibody recognizes Human antigen. The Anti-ABCB6 antibody has been shown to work in the following applications: Immunocytochemistry, Immunohistochemistry, Immunohistochemistry - fixed, and Western Blot.
Description
Description: Rabbit IgG polyclonal antibody for ATP-binding cassette sub-family B member 6, mitochondrial(ABCB6) detection. Tested with WB, IHC-P, ICC in Human.
Background: ABCB6, ATP-binding cassette sub-family B member 6, mitochondrialis a protein that in humans is encoded by the ABCB6 gene. The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette(ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies(ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. This half-transporter likely plays a role in mitochondrial function. Localized to 2q26, this gene is considered a candidate gene for lethal neonatal metabolic syndrome, a disorder of mitochondrial function