The Rabbit anti BCL-W Polyclonal antibody from MyBioSource.com is a Rabbit Polyclonal antibody. This antibody recognizes Human, Mouse, Rat, Bovine, Canine, and Chicken/Bird antigen. The Rabbit anti BCL-W Polyclonal antibody has been shown to work in the following applications: ELISA, Immunohistochemistry, and Western Blot.
Description
BCL-w is a member of the Bcl-2 family. The gene codes for a 21 kDa protein which is essential for the regulation of cellular survival, and that is up-regulated in different human tumors, such as gastric and colorectal carcinomas. Inhibition of AKT activity may promote apoptosis through the down-regulation of Bcl-w protein and the consequential reduction in interaction of Bcl-w with pro-apoptotic members of the Bcl-2 family