The HIG2 Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to HIGD2A, and Miscellaneous. This antibody recognizes Human, and Mouse antigen. The HIG2 Antibody has been shown to work in the following applications: ELISA, and Western Blot.
Description
HIG2 Antibody: HIG1 and HIG2 (Hypoxia-inducible gene 1 and 2, respectively) are known to be induced by hypoxic conditions. HIG2 is induced by hypoxia and by glucose deprivation in cultured cells. In addition, tumor xenografts derived from human cervical cancer cells display increased expression of HIG1 and HIG2 when they are deprived of oxygen. Unlike HIG2, which is ubiquitously expressed and might be an activator and target of the canonical Wnt pathway, the function and the mechanisms underlying its regulation of HIG1 still remained unknown. The putative link between hypoxia and an oncogenic signaling pathway might play an important role in tumorigenesis