The Anti-human FGF1 antibody from MyBioSource.com is a Rabbit Polyclonal antibody to FGF1, and HBGF-1. This antibody recognizes Human antigen. The Anti-human FGF1 antibody has been shown to work in the following applications: Block/Neutralize/Inhibit, ELISA, Immunohistochemistry, Immunohistochemistry - fixed, Immunoprecipitation, and Western Blot.
Description
Description: Rabbit IgG polyclonal antibody for Fibroblast growth factor 1(FGF1) detection. Tested with WB, IHC-P, ELISA, Neu, IP in Human.
Background: Fibroblast growth factor 1(acidic), also known as FGF1/ECGF/HBGF1, is a human gene which is mapped to 5q31. Human FGF1 shares 96% amino acid sequence homology with both rat and mouse. The protein encoded by this gene is a member of the fibroblast growth factor(FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein functions as a modifier of endothelial cell migration and proliferation, as well as an angiogenic factor. It acts as a mitogen for a variety of mesoderm- and neuroectoderm-derived cells in vitro, thus is though to be involved in organogenesis. Additionally, Acidic fibroblast growth factor is derived from beta-endothelial cell growth factor(ECGFB) by posttranslational processing. Alpha-ECGF is also derived from ECGFB in the same manner