The Anti-SOCS1 antibody from MyBioSource.com is a Rabbit Polyclonal antibody to JAB, SOCS 1, and SOCS1. This antibody recognizes Human, Mouse, and Rat antigen. The Anti-SOCS1 antibody has been shown to work in the following applications: Immunohistochemistry, Immunohistochemistry - fixed, and Western Blot.
Description
Description: Rabbit IgG polyclonal antibody for Suppressor of cytokine signaling 1(SOCS1) detection. Tested with WB, IHC-P in Human, Mouse, Rat.
Background: Suppressor of cytokine signaling 1(SOCS1), also known as Jak-binding protein(JAB), is a negative regulator to a subset of protein-tyrosine kinases. This 211-amino acid protein has a molecular mass of about 23.5 kD. The TEC-binding region of SOCS1 resides in the N terminus. SOCS1 associates with Tec and suppresses its kinase activity. The SOCS1 gene is intronless and is mapped to on chromosome 16p13.13. SOCS1 regulates the JAK/STAT signal-transduction pathway. Moreover, it contributes to protection against hepatic injury and fibrosis, and may also protect against hepatocarcinogenesis