The HVCN1 Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to Hv1, HVCN1, Miscellaneous, and VSOP. This antibody recognizes Human, Mouse, and Rat antigen. The HVCN1 Antibody has been shown to work in the following applications: ELISA, Immunohistochemistry, and Western Blot.
Description
HVCN1 (hydrogen voltage-gated channel 1), a voltage gated proton channel protein that is highly expressed in immune tissues, mediates the proton conductances required by phagocytic leukocytes for the oxidative burst that underlies microbial killing. HVCN1 moderates the voltage-dependent proton permeability of excitable membranes by allowing the flow of protons in accordance to their electrochemical gradient. HVCN1 is sensitive to zinc ions, and can be inhibited by them. HVCN1 may represent a new therapeutic target for B cell malignancies on continued signaling via the B cell antigen receptor