The Anti-TNF beta antibody from MyBioSource.com is a Rabbit Polyclonal antibody to LTA, Lymphotoxin alpha, TNF beta, TNFB, and Tnfsf1b. This antibody recognizes Human antigen. The Anti-TNF beta antibody has been shown to work in the following applications: Western Blot.
Description
Description: Rabbit IgG polyclonal antibody for Lymphotoxin-alpha(LTA) detection. Tested with WB in Human.
Background: Lymphotoxin(previously known as tumor necrosis factor-beta) is a lymphokine cytokine. It is a protein that is produced by Th1 type T-cells and induces vascular endothelial cells to change their surface adhesion molecules to allow phagocytic cells to bind to them. Lymphotoxin is homologous to Tumor Necrosis Factor beta, but secreted by T-cells. It is paracrine due to the small amounts produced. The effects are similar to TNF-alpha, but TNF-beta is also important for the development of lymphoid organs. Nedwin et al.(1985) found that TNFA and TNFB are closely linked on chromosome 6. Study of hybrid cells made with rearranged human chromosome 6 showed that both TNFA and TNFB map to the 6p23-q12 segment