MyBioSource.com's Rabbit anti-human stromal interaction molecule 1 polyclonal Antibody is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: ELISA, Immunofluorescence, Immunohistochemistry, Immunoprecipitation, and Western Blot. The Rabbit anti-human stromal interaction molecule 1 polyclonal Antibody was generated using GOK, and STIM1 as the antigen and it reacts with Human, Mouse, and Bovine.
Description
Plays a role in mediating store-operated Ca2+ entry (SOCE), a Ca2+ influx following depletion of intracellular Ca2+ stores. Acts as Ca2+ sensor in the endoplasmic reticulum via its EF-hand domain. Upon Ca2+ depletion, translocates from the endoplasmic reticulum to the plasma membrane where it activates the Ca2+ release-activated Ca2+ (CRAC) channel subunit, TMEM142A/ORAI1