MyBioSource.com's Cardiotrophin 1 antibody is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: Block/Neutralize/Inhibit, ELISA, and Western Blot. The Cardiotrophin 1 antibody was generated using cardiotrophin 1, and CTF1 as the antigen and it reacts with Human.
Description
Affinity purified Rabbit polyclonal Cardiotrophin 1 antibody
CT-1 is a member of the IL6 family of cytokines which also includes LIF, CNTF, OSM (Oncostatin M), IL11, IL6 and possibly NT-1/ BSF-3. CT-1 is a pleiotropic cytokine which is expressed in various tissues including the adult heart, skeletal muscle, ovary, colon, prostate and fetal lung and signals through the LIF receptor and the gp130 receptor subunit. CT-1 has the ability to induce cardiac myocyte hypertrophy, and enhances the survival of cardiomyocyte and different neuronal populations. Biologically active human CT-1 is synthesized as a 201 amino acid polypeptide lacking a hydrophobic N-terminal secretion signal sequence