Mouse Anti Human Programmed Cell Death 12 from MyBioSource.com

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Mouse Anti Human Programmed Cell Death 12

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MyBioSource.com's Mouse Anti Human Programmed Cell Death 12 is a Mouse monoclonal antibody. This antibody has been shown to work in applications such as: ELISA, Immunohistochemistry, and Western Blot.

Description

Introduction: PDCD12 (AVEN) represents a new class of cell death regulator. PDCD12 is a conserved intracellular membrane protein which blocks apoptosis impeded by Apaf-1 mediated caspase activation. BAD and Bcl-2 also interact with PDCD12 to prevent apoptosis. PDCD12 is expressed in a wide variety of normal tissues including the heart, skeletal muscle, kidney, liver, testis, and also in diseases such as cancer