MyBioSource.com's IGF BP5 antibody is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: Block/Neutralize/Inhibit, ELISA, and Western Blot. The IGF BP5 antibody was generated using IBP5, and IGFBP5 as the antigen and it reacts with Rat.
Description
Affinity purified Rabbit polyclonal IGF BP5 antibody
IGF-BPs controls the distribution, function and activity of IGFs in various cell tissues and body fluids. Currently there are seven named IGF-BPs that form high affinity complexes with both IGF-I and IGF-II. IGF-BP5 is a 28.6 kDa cysteine-rich secreted protein produced by vascular smooth muscle cells. It is the major IGF-binding protein present in bone tissue and helps potentiate the action of IGF-I on smooth muscle cells, fibroblasts or osteoblasts. Data shows that IGFBP-5 acts as a growth inhibitor and pro-apoptotic agent in breast cancer cells