MyBioSource.com's CD8 Antibody is a Mouse monoclonal antibody. The CD8 Antibody was generated using CD8, and CD8A as the antigen. It reacts with Human. This antibody has been shown to work in applications such as: ELISA, and Flow Cytometry.
Description
Background: CD8 T cell surface antigen is heterodimer of an alpha and a beta chain linked by two disulfide bonds.It belongs type I membrane protein. Selectively expressing of CD8 on a subset of T cells leads to CD8 T cell development. Through identifying cytotoxic/suppressor T-cells that interact with MHC class I bearing targets, CD8 is thought to play a role in the process of T-cell mediated killing. Veillette et al (1988) found the CD8 is associated with the internal membrane tyrosine-protein kinase p56lck