MyBioSource.com's Anti-MTA1 antibody is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: Immunohistochemistry, Immunohistochemistry - fixed, and Western Blot. The Anti-MTA1 antibody was generated using MTA1 as the antigen and it reacts with Human, Mouse, and Rat.
Description
Description: Rabbit IgG polyclonal antibody for Metastasis-associated protein MTA1(MTA1) detection. Tested with WB, IHC-P, IHC-F in Human, Mouse, Rat.
Background: Metastasis-associated protein MTA1 is a protein that in humans is encoded by the MTA1 gene. This gene encodes a protein that was identified in a screen for genes expressed in metastatic cells, specifically, mammary adenocarcinoma cell lines. Expression of this gene has been correlated with the metastatic potential of at least two types of carcinomas although it is also expressed in many normal tissues.By fluorescence in situ hybridization, mapped the MTA1gene to chromosome 14q32.3. MTA1 is a component of the chromatin remodeling complex that influences gene transcription by modulating target gene chromatin. MTA1 is widely upregulated in many carcinomas