MyBioSource.com's PRP8 Pre-mRNA Processing Factor 8 Homolog (PRPF8, PRP8, hPRP8, PRPC8, RP13) is a Human, and Mouse monoclonal antibody. The PRP8 Pre-mRNA Processing Factor 8 Homolog (PRPF8, PRP8, hPRP8, PRPC8, RP13) Antibody was generated using PRP8, and Prpf8 as the antigen. It reacts with Human, Mouse, and Rat. This antibody has been shown to work in applications such as: Flow Cytometry, Immunocytochemistry, Super Shift Assay, and Western Blot.
Description
Pre-mRNA splicing occurs in 2 sequential transesterification steps. The protein encoded by this gene is a component of both U2- and U12-dependent spliceosomes, and found to be essential for the catalytic step II in pre-mRNA splicing process. It contains several WD repeats, which function in protein-protein interactions. This protein has a sequence similarity to yeast Prp8 protein. This gene is a candidate gene for autosomal dominant retinitis pigmentosa