MYH7 (A4.840) Antibody sc-53089 from Santa Cruz Biotechnology, Inc.

Product Specs
ItemMYH7 (A4.840) Antibody
CompanySanta Cruz Biotechnology, Inc.
Price $316.00Supplier Page View Company Product Page
Catalog Numbersc-53089
Antibody TypePrimary Antibodies
NCBI Gene AliasesSPMD, SPMM, MYH-beta/slow, CMYP7A, CMYP7B, betaMHC, myHC-slow, CMD1S, MYHCB, Myhc-b, beta-MHC, B-MHC, myHC-beta, MPD1, CMH1, Myhcb, MyHC-I
Quantity200 µg/ml
CloneA4.840
ApplicationsWB, IP, IF, IHC(P)
Reactivitymouse, rat, human, rabbit, avian
ClonalityMonoclonal
Conjugate/TagUnconjugated
FormatPurified
Hostmouse
NCBI Full Gene Namemyosin heavy chain 7, myosin, heavy polypeptide 7, cardiac muscle, beta
Targetadult skeletal muscle myosin
IsotypeIgM

Questions and Answers

What applications has the MYH7 antibody been used for in research studies?

The MYH7 antibody has been shown to work in various applications, including Western blotting, immunofluorescence, immunohistochemistry, and immunoprecipitation, as evidenced by its use in studies examining cardiac remodeling and hypertrophy in mouse models and human tissues.

Can this antibody be used to study cardiac hypertrophy in mouse models?

Yes, the MYH7 antibody has been utilized in studies investigating cardiac hypertrophy, such as in the research by Xiong et al. (2017), where it was used to assess protein expression in the context of pressure overload-induced cardiac remodeling.

Is the MYH7 antibody effective for immunostaining in human tissues?

The MYH7 antibody has been effectively used for immunostaining in human tissues, as demonstrated in studies like that of Yu et al. (2024), where it was employed to analyze cardiac hypertrophy and apoptosis in response to radiation.

What species does the MYH7 antibody react with?

The MYH7 antibody is reactive with multiple species, including humans, mice, rats, chickens, and rabbits, making it versatile for various experimental models in cardiac research.

Santa Cruz Biotechnology, Inc.

10410 Finnell Street

Dallas, Texas 75220

United States

Phone: 1-800-457-3801
831-457-3801

Company Profile

Website: http://www.scbt.com/

(1) Amelioration of CKD-induced cardiomyocyte hypertrophy by pegmolesatide: involvement of JAK2/STAT3 inhibition and mitochondrial protectionFront PharmacolMay 13, 2026Xinyu Zhang, Sufang Li, Tingru Lin, Liangying Gan, Hanze Zheng, Li Zhu, Li Zuo(Cell Signaling Technology, 9,145; 1:1,000), anti-BNP (Abcam, ab19645; 1:800), anti-β-MHC (Santa Cruz, sc-53089; 1:500), and anti-GAPDH (Proteintech, 60004-1-Ig; 1:5,000) as a loading control. Subsequent to three

(2) PGAM2 Regulates Sepsis-Induced Diaphragmatic Atrophy via the JAK2/STAT3 PathwayBiomedicinesMay 9, 2026Yun Chu, Xinrun Yuan, Xiaopo Gao, Jinlong Luo(Santa Cruz Biotechnology, Dallas, TX, USA, sc-59854, 1:1000), and mouse anti-MYH antibody (B-5) (Santa Cruz Biotechnology, sc-53089, 1:1000), a pan-myosin heavy chain antibody that does not distinguish between different muscle fiber

(3) Development of conditional-siRNA programmable riboswitch for targeting adverse cardiac remodelingMol Ther Nucleic AcidsAugust 5, 2025Priyanka Gokulnath, Ane M. Salvador, Caleb Graham, Si-ping Han, Guoping Li, Ramaswamy Kannappan, Christopher Azzam, Michail Spanos, Lisa Scherer, Palaniappan Sethu, et al.2614S), NFATc1 NFATc1(Sigma-Aldrich, cat. no. SAB2101576), MYH7 (Santa Cruz Biotechnology, cat. no. sc-53089), phospho p44/42 MAPK (Erk1/2) (Thr202/Tyr204) (Cell Signaling Technology, cat. no. 4370S), and P44/42

(4) Perinatal Inflammation Results in Sex-Dependent Cardiac DysfunctionJournal of Cardiovascular Development and DiseaseNovember 1, 2024Leeann R. Pavlek, Kathryn M. Heyob, Nitya R. Jacob, Saichidroopi Korada, Zahra Khuhro, Aiman Q. Khan, Terri A. Shaffer, Sara Conroy, Markus Velten, Lynette K. Rogersprimary antibodies (MYH6, 1:200, sc-168676, Santa Cruz Biotechnology, Dallas, TX, USA), (MYH7, 1:200, sc-53089, Santa Cruz Biotechnology, Dallas, TX, USA). The membranes were subsequently probed with species-specific

(5) Endurance exercise-induced histone methylation modification involved in skeletal muscle fiber type transition and mitochondrial biogenesisScientific ReportsSeptember 10, 2024Jialin Li, Sheng Zhang, Can Li, Xiaoxia Zhang, Yuhui Shan, Ziyi Zhang, Hai Bo, Yong ZhangTechnology, USA, #ab191838), COX IV (1:1000, Abcam, USA, #ab209727), MYH7 (1:1000, Santa Cruz, USA, #sc-53089), MYH4 (1:1000, Proteintech, USA, #20,140–1-AP), JMJD3 (1:500, MyBioSource, USA, #MBS150629), EZH2 (1:1000,

(6) EEPD1 attenuates radiation-induced cardiac hypertrophy and apoptosis by degrading FOXO3A in cardiomyocytesActa biochimica et biophysica SinicaAugust 29, 2024Yu K, Su X, Zhou T, Cai X, Zhang M.3498; CST, Beverly, USA), anti-Bax (1:1000, 14796; CST), anti-GAPDH (1:1000, 5174; CST), Myh7 (1:1000, sc-53089; Santa Cruz, Santa Cruz, USA), anti-TGF Beta1 (1:1000, 21898-1-AP; Proteintech, Wuhan, China), anti-BNP

(7) Liraglutide ameliorates TAC-induced cardiac hypertrophy and heart failure by upregulating expression level of ANP expressionHeliyonJune 15, 2024Ruisha Li, Keyin Zhang, Zhenjun Xu, Yanrong Yu, Dongjin Wang, Kai Li, Wenxue Liu, Jun Pan(1:2000, ab8245, Abcam), ANP (1:500, AP8534A, Abcepta), BNP (1:500, DF6902, Affinit), MYH7 (1:1000, sc-53089, Santa cruz), Col1a (1:1000, ab6308, Abcam), Col3a1 (1:1000, ab7778, Abcam), TGFβ (1:1000, ab215715,

(8) Thrombospondin-1 Drives Cardiac Remodeling in Chronic Kidney DiseaseJACC. Basic to translational scienceMay 1, 2024Julovi SM, Trinh K, Robertson H, Xu C, Minhas N, Viswanathan S, Patrick E, Horowitz JD, Meijles DN, Rogers NM.(#PA5-98294), and cardiac myosin heavy chain (#MA1-26180) were from Invitrogen. Myosin heavy chain (MHC)-β (#sc-53089) was from Santa Cruz Biotechnology. Protein was visualized on an Odyssey LCx Imaging System (Licor).

(9) Human induced pluripotent stem cell-derived closed-loop cardiac tissue for drug assessmentiScienceFebruary 16, 2024Junjun Li, Ying Hua, Yuting Liu, Xiang Qu, Jingbo Zhang, Masako Ishida, Noriko Yoshida, Akiko Tabata, Hayato Miyoshi, Mikio Shiba, et al.Santa Cruz Biotechnology, Dallas, TX, USA), anti-connexin 43 (Cx43; 1:200; C6219; Sigma-Aldrich), or anti-β-MHC (1:100; SC-53089; Santa Cruz Biotechnology) at 4°C overnight. Thereafter, the tissues were rinsed with PBS and incubated

(10) Low‐dose exercise protects the heart against established myocardial infarction via IGF‐1‐upregulated CTRP9 in male miceMedComm (2020)December 1, 2023Yanzhen Tan, Pan Feng, Lele Feng, Lei Shi, Yujie Song, Jian Yang, Weixun Duan, Erhe Gao, Jincheng Liu, Dinghua Yi, et al.(ABN‐PAB13422, Abnova), CTRP9 (customized by Genscript), α‐SMA (ab5694, Abcam), TGF‐β (ab92486, Abcam), β‐MHC (sc‐53089, Santa Cruz), c‐Fos (2250T, CST), FOXP1 (ab134055, Abcam), NR2F2 (ab211777, Abcam), and β‐actin (AT0001)

(11) Effects on Goat Meat Extracts on α-Glucosidase Inhibitory Activity, Expression of Bcl-2-Associated X (BAX), p53, and p21 in Cell Line and Expression of Atrogin-1, Muscle Atrophy F-Box (MAFbx), Muscle RING-Finger Protein-1 (MuRF-1), and Myosin Heavy Chain-7 (MYH-7) in C2C12 MyoblstsFood science of animal resourcesMarch 1, 2023Kang J, Kim S, Lee Y, Oh J, Yoon Y.Santa Cruz Biotechnology), mouse-anti-MuRF-1 (sc-398608, 1:300; Santa Cruz Biotechnology), and mouse-anti-MYH-7 (sc-53089, 1:200; Santa Cruz Biotechnology)] were used. Mouse-anti-β-actin (sc-81178, 1:1,000, Santa Cruz Biotechnology)

(12) Potential nutritional healthy-aging strategy: enhanced protein metabolism by balancing branched-chain amino acids in a finishing pig modelFood & functionJune 6, 2022Zhang L, Guo Q, Duan Y, Wang W, Yang Y, Yin Y, Gong S, Han M, Li F, Yin Y.

(13) Ginsenoside compound K ameliorates palmitate-induced atrophy in C2C12 myotubes via promyogenic effects and AMPK/autophagy-mediated suppression of endoplasmic reticulum stressJournal of ginseng researchMay 1, 2022Kim TJ, Pyun DH, Kim MJ, Jeong JH, Abd El-Aty AM, Jung TW.

(14) Comprehensive Analysis of Long Noncoding RNA Modified by m(6)A Methylation in Oxidative and Glycolytic Skeletal MusclesInternational journal of molecular sciencesApril 21, 2022Wang S, Tan B, Xiao L, Zhao X, Zeng J, Hong L, Yang J, Cai G, Zheng E, Wu Z, et al.Western blotting was performed according to previous reports [81]. The primary antibodies used include: MyHC I (sc-53089; Santa Cruz; Delaware, Santa Cruz, CA, USA), MyHC IIb (A15293; ABclonal; Wuhan, China), MyHC IIa (A15292;

(15) Long noncoding RNA H19 suppresses cardiac hypertrophy through the MicroRNA-145-3p/SMAD4 axisBioengineeredFebruary 1, 2022Wang H, Lian X, Gao W, Gu J, Shi H, Ma Y, Li Y, Fan Y, Wang Q, Wang L.

(16) Targeted overexpression of PPARγ in skeletal muscle by random insertion and CRISPR/Cas9 transgenic pig cloning enhances oxidative fiber formation and intramuscular fat depositionFASEB journal : official publication of the Federation of American Societies for Experimental BiologyFebruary 1, 2021Gu H, Zhou Y, Yang J, Li J, Peng Y, Zhang X, Miao Y, Jiang W, Bu G, Hou L, et al.

(17) The nuclear envelope protein Net39 is essential for muscle nuclear integrity and chromatin organizationNature communicationsJanuary 29, 2021Ramirez-Martinez A, Zhang Y, Chen K, Kim J, Cenik BK, McAnally JR, Cai C, Shelton JM, Huang J, Brennan A, et al.used: SUN2 (Sigma, MABT880), Lamin A (Abcam, ab26300), LEMD2 (Sigma, HPA017340), MYH7 (Santa Cruz, sc-53089), MYH2 (Santa Cruz, sc-53096), MYH4 (Proteintech, 20140-1-AP), PAX7 (DSHB, PAX7-c), SV2 (DSHB, SV2-c),

(18) MicroRNA-494-3p inhibits formation of fast oxidative muscle fibres by targeting E1A-binding protein p300 in human-induced pluripotent stem cellsScientific reportsJanuary 13, 2021Iwasaki H, Ichihara Y, Morino K, Lemecha M, Sugawara L, Sawano T, Miake J, Sakurai H, Nishi E, Maegawa H, et al.antibodies used in this study were as follows: Mouse anti-MYOD (sc-377460), anti-myosin heavy chain 7 (MYH7; sc-53089), anti-β-actin (sc-47778), monoclonal antibodies (mAbs), rabbit anti-p300 (sc-584), anti-SIRT1 (H-300),

(19) Isoliquiritigenin attenuates diabetic cardiomyopathy via inhibition of hyperglycemia-induced inflammatory response and oxidative stressPhytomedicine : international journal of phytotherapy and phytopharmacologyNovember 1, 2020Gu X, Shi Y, Chen X, Sun Z, Luo W, Hu X, Jin G, You S, Qian Y, Wu W, et al.

(20) An α₂-adrenoceptor agonist: Dexmedetomidine induces protective cardiomyocyte hypertrophy through mitochondrial-AMPK pathwayInternational Journal of Medical SciencesSeptember 9, 2020Xiaojian Weng, Hua Liu, Xiaodan Zhang, Qianqian Sun, Cheng Li, Minglu Gu, Yanyifang Xu, Shitong Li, Weiwei Li, Jianer DuSanta Cruz Biotechnology, Inc.), anti-BNP (rabbit pAb; 1:500; ab19645; Abcam), anti-MYH7 (mouse mAb; 1:300; sc-53089; Santa Cruz Biotechnology, Inc.), anti-Erk1/2 (rabbit mAb; 1:1000; #9102), anti-phospho-Erk1/2 (Thr202/Thr204)

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MYH7 (A4.840) Antibody

MYH7 (A4.840) Antibody from Santa Cruz Biotechnology, Inc.

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Santa Cruz Biotechnology, Inc.

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MYH7 (A4.840) Antibody from Santa Cruz Biotechnology, Inc.

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