Magic™ Anti-KMT6/EZH2 (Phospho S21) polyclonal antibody from Creative Diagnostics

Yes, the Magic™ Anti-KMT6/EZH2 (Phospho S21) polyclonal antibody is specifically designed to target the phosphorylated form of EZH2, particularly around Serine 21. This makes it suitable for studying the phosphorylation status of EZH2 in human samples.

This antibody has been shown to work in various applications, including Immunocytochemistry, Immunofluorescence, and Immunohistochemistry on paraffin-embedded sections. Researchers can utilize it to visualize EZH2 phosphorylation in different cellular contexts.

Yes, the Magic™ Anti-KMT6/EZH2 (Phospho S21) antibody is reactive with both Homo sapiens (human) and Mus musculus (mouse), allowing for comparative studies between these species.

Phosphorylation of EZH2 by AKT1 has been shown to reduce its methyltransferase activity. This modification can have significant implications for its role in gene regulation and cellular processes, making this antibody valuable for studies investigating the functional consequences of EZH2 phosphorylation.