HSP90alpha (D1A7) Rabbit mAb 8165S from Cell Signaling Technology

Product Specs
ItemHSP90alpha (D1A7) Rabbit mAb
CompanyCell Signaling Technology
Price $339.00 Inquire
Catalog Number8165S
Quantity100 µl
ApplicationsW
ReactivityH, R, Hm, Mk, B, Pg
ClonalityMonoclonal
TargetHSP90A
HostRabbit
NCBI Gene AliasesEL52, HEL-S-65p, HSP86, HSP89A, HSP90A, HSP90N, HSPC1, HSPCA, HSPCAL1, HSPCAL4, HSPN, Hsp103, Hsp89, Hsp90, LAP-2, LAP2
NCBI Full Gene Nameheat shock protein 90 alpha family class A member 1
Research AreaProtein Folding and Trafficking
IsotypeIgG
CloneD1A7
Molecular Weight90

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Cell Signaling Technology

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Danvers, Massachusetts 01923

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Phone: 877-616-CELL
Phone: 978-867-2388
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Website: http://www.cellsignal.com/

Website: Technical Support

(1) Non-Invasive Physical Plasma as an Oncological Therapy Option: Modulation of Cancer Cell Growth, Motility, and Metabolism Without Induction of Cancer Resistance FactorsCancers (Basel)October 31, 2025Yanqing Wang, Benedikt Eggers, Alexander Abazid, Holger H. H. Erb, Matthias B. StopeNo.: #4873, Cell Signaling Technology, Frankfurt, Germany; Anti-HSP90a (Rabbit, 1:10,000, Cat. No.: #8165, Cell Signaling Technology, Frankfurt, Germany); Anti-HSP90b (Rabbit, 1:10,000, Cat. No.: #5087, Cell Signaling Technology

(2) Beyond Antagonism: IL-4 Exploits TNF signaling to Shape Its Gene Expression Signature in Monocytes and MacrophagesbioRxivJuly 31, 2025Ruoxi Yuan, Chao Yang, Bikash Mishra, David Oliver, Richard Bell, Lionel B. Ivashkivwere from Cell Signaling Technology: STAT6 (5397S), phosphor-STAT6 (9361S), C/EBPβ (3087S), HSP90α (8165S), IRF1 (8478S), from Sigma-Aldrich: α-Tubulin (T9026) and from Abcam: Lamin B1 (ab16048). RNA sequencing Libraries

(3) C1QL1 inhibits breast cancer through the HSP90α/VCP-ERS/UPR axisExperimental & molecular medicineJune 1, 2025Zhang N, Shao Q, Xiang X, Yan C, Tao D, Li Q, Rong H, Zhao Y, Xiang T, Zeng X.anti-β-actin (sc-47778, Santa Cruz), anti-C1QL1 (orb1260, Biorbyt), anti-Calnexin (2679, CST), anti-HSP90α (8165, CST), anti-VCP (2648, CST), anti-P4HB (3501, CST), anti-ERP57 (2881, CST), anti-GRP94 (2104, CST),

(4) Hsp90 C-terminal domain inhibition enhances ferroptosis by disrupting GPX4-VDAC1 interaction to increase HMOX1 release from oligomerized VDAC1 channelsRedox BiologyMay 29, 2025Jieyou Li, Guibing Wu, Hairou Su, Manfeng Liang, Shengpei Cen, Yandan Liao, Xiangjun Zhou, Guantai Xie, Zihao Deng, Wenchong Tan, et al.(70081S), SLC7A11 (12691S), FTH1 (4393S), COXⅣ (4850S), β-Tubulin (2128s), LC3 (4108S) and Hsp90α (8165s) were acquired from Cell Signaling Technology (Danvers, MA, USA). Antibodies against GPX4 (ab125066),

(5) HSP90 stabilizes visual cycle retinol dehydrogenase 5 in the endoplasmic reticulum by inhibiting its degradation during autophagyJournal of Biological ChemistryFebruary 1, 2025Xiaolin Jia, Yuxuan Wang, Mingjun Jiang, Dan-Dan Chen, Guohui Shang, Baixue Liu, Mengjiao Xue, Youfei Lang, Guiling Zhou, Yichen Dong, et al.(#C6628) was from Sigma-Aldrich. The rabbit monoclonal antibodies against HSP90 (#4877s), HSP90ɑ (#8165), HSP90β (#5087), and rat polyclonal antibodies against HSP70 (#4873) were purchased from Cell Signaling Technology

(6) Adunctin E from Conamomum rubidum Induces Apoptosis in Lung Cancer via HSP90AA1 Modulation: A Network Pharmacology and In Vitro StudyInternational Journal of Molecular SciencesOctober 22, 2024Iksen Iksen, Natsaranyatron Singharajkomron, Hien Minh Nguyen, Hanh Nhu Thi Hoang, Duc Viet Ho, Varisa Pongrakhananonincubation with corresponding secondary antibodies at room temperature for 2 h. Rabbit HSP90AA1 (1:1000, CST#8165), mouse anti-GAPDH (1:1000, CST# 97166), HRP-conjugated anti-rabbit (1:1000, CST#7074), and HRP-conjugated

(7) Alleviating iatrogenic effects of paclitaxel via antiinflammatory treatmentVascular MedicineAugust 1, 2024Mengwei Zhang, Saran Lotfollahzadeh, Nagla Elzinad, Xiaosheng Yang, Murad Elsadawi, Adam C Gower, Mostafa Belghasem, Tarek Shazly, Vijaya B Kolachalama, Vipul C ChitaliaCD137 (cat no. 34594S; Cell Signaling), MCP-1 (cat no. 81559S; Cell Signaling), and HSP90 (cat no. 8165S; Cell Signaling). Proteins were visualized with chemiluminescent substrate (cat no. 34577; Thermo Scientific,

(8) Combined treatment with cetuximab and STA9090 has synergistic anticancer effects on human non-small cell lung cancerActa Biochimica et Biophysica SinicaJuly 1, 2024Wanjun Lu, Lixia Liu, Xiang Kang, Kangkang Ren, Ye Huang, Minzhang Cheng, Xiaolei Li, Fei Xu, Xinping XuShanghai, China). The following antibodies from Cell Signaling Technology (Beverly, USA) were used: Hsp90α (8165s), Hsp90β (5087s), total EGFR (4267s), total ERK (4695s), total AKT (4691s), PARP (9542s), cleaved-PARP

(9) Discovery of a new class of cell-penetrating peptides by novel phage display platformScientific ReportsJune 11, 2024Jinsha Liu, John Heddleston, Douglas Raymond Perkins, Jack Jia Hua Chen, Ahmadreza Ghanbarpour, Bill William Smith, Rebecca Miles, Eitaro Aihara, Sepideh Afsharanti-clathrin, Cat. No. 4796S, Cell signaling; anti-EEA1, Cat. No. ab2900, Abcam; anti-HSP90, Cat. No. 8165S, Cell signaling; anti-LAMP1, Cat. No. ab24170, Abcam; anti-MEK1/2, Cat. No. 8727S, cell signaling. Secondary

(10) Alleviating iatrogenic effects of paclitaxel via antiinflammatory treatmentVasc MedApril 16, 2024Mengwei Zhang, Saran Lotfollahzadeh, Nagla Elzinad, Xiaosheng Yang, Murad Elsadawi, Adam C Gower, Mostafa Belghasem, Tarek Shazly, Vijaya B Kolachalama, Vipul C ChitaliaCD137 (cat no. 34594S; Cell Signaling), MCP-1 (cat no. 81559S; Cell Signaling), and HSP90 (cat no. 8165S; Cell Signaling). Proteins were visualized with chemiluminescent substrate (cat no. 34577; Thermo Scientific,

(11) Inhibition of glycogen synthase kinase-3 enhances NRF2 protein stability, nuclear localisation and target gene transcription in pancreatic beta cellsRedox BiolMarch 7, 2024Chinmai Patibandla, Lidy van Aalten, Albena T. Dinkova-Kostova, Tadashi Honda, Antonio Cuadrado, Raquel Fernández-Ginés, Alison D. McNeilly, John D. Hayes, James Cantley, Calum SutherlandTechnologies,2032,Lot 6,Rabbit,1:1000 TBP,Abcam,Ab300656,GR3459461-3,Mouse,1:1000 HSP90α,Cell Signalling Technologies,8165,Lot 1,Rabbit,1:1000 GAPDH,Cell Signalling Technologies,5174,Lot 8,Rabbit,1:1000 List of primary

(12) METTL18 functions as a Phenotypic Regulator in Src-Dependent Oncogenic Responses of HER2-Negative Breast CancerInternational journal of biological sciencesJanuary 1, 2024Kim HG, Kim JH, Kim KH, Yoo BC, Kang SU, Kim YB, Kim S, Paik HJ, Lee JE, Nam SJ, et al.4806), anti-HER2 (# 2242), anti-Myc (# 2276), anti-PRMT1 (# 2449), anti-Flag (# 8146), anti-HSP90 (# 8165), anti-tubulin (# 2128), HRP-conjugated anti-mouse IgG (#91196), and anti-β-actin (# 4967) were purchased

(13) ß-D-Glucan promotes NF-κB activation and ameliorates high-LET carbon-ion irradiation-induced human umbilical vein endothelial cell injuryTurkish Journal of Medical SciencesDecember 12, 2023FANG LIU, YANTING WEI, ZHUANZI WANGUSA). Antibodies against p-Src (Tyr416) (6943S), Src (13198S), MnSOD (13141S), BRCA2 (10741S), Hsp90α (8165S), Bax (5023S), Bcl-2 (15071S), β-actin (3700S), HRP-conjugated goat antimouse secondary antibody (7076S),

(14) HSP90 C-terminal domain inhibition promotes VDAC1 oligomerization via decreasing K274 mono-ubiquitination in Hepatocellular CarcinomaNeoplasia (New York, N.Y.)October 1, 2023Zhang J, Liu L, Li Y, Huang Y, Xiao S, Deng Z, Zheng Z, Li J, Liang M, Xie G, et al.VDAC1 antibodies for VDAC1 monoubiquitination (1:1000, sc39099, Santa Cruz, CA, USA), Hsp90α (1:1000, 8165S, Cell Signaling Technology, MA, USA), β-actin (1:6000, RM2001, Ray Antibody Biotech, Beijing, China),

(15) Alleviating iatrogenic effects of paclitaxel via anti-inflammatory treatmentResearch SquareMay 26, 2023Mengwei Zhang, Saran Lotfollahzadeh, Nagla Elzinad, Xiaosheng Yang, Murad Elsadawi, Adam Gower, Mostafa Belghasem, Tarek Shazly, Vijaya B. Kolachalama, Vipul ChitaliaCell Signaling), CD137 (34594S; Cell Signaling), MCP-1 (Cat No. 81559S; Cell Signaling), HSP90 (Cat No. 8165S; Cell Signaling). Proteins were visualized with chemiluminescent substrate (Cat No. 34577; Thermo Scientific)

(16) Role of heat shock protein 90 as an antiviral target for swine enteric coronavirusesVirus ResearchMay 1, 2023Zhuangzhuang Zhao, Ya-Qing Zhang, Ling-Dong Xu, Lihua Xiao, Yaoyu Feng, Bin Wang, Yao-Wei HuangCytoTox 96® Non-Radioactive Cytotoxicity Assay (G1780) was purchased from Promega. Myc-tag (#2278), Hsp90α (#8165) rabbit monoclonal antibody, Hsp90β antibody (#5087), Hsp70 antibody (#4872), GSDMD antibody (#39,754)

(17) Heat shock protein 90 facilitates SARS-CoV-2 structural protein-mediated virion assembly and promotes virus-induced pyroptosisJournal of Biological ChemistryMay 1, 2023Zhuangzhuang Zhao, Ling-Dong Xu, Fei Zhang, Qi-Zhang Liang, Yajuan Jiao, Fang-Shu Shi, Biao He, Pinglong Xu, Yao-Wei HuangAssay (G1780) was purchased from Promega. Myc-tag (71D10, #2278), myc-tag (9B11, #2276), Hsp90α (D1A7, #8165) rabbit monoclonal antibody, Hsp90β antibody (#5087), Hsp70 antibody (#4872), GSDMDantibody (#39754),

(18) Development of the first geldanamycin-based HSP90 degradersFrontiers in chemistryJanuary 1, 2023Wurnig S, Vogt M, Hogenkamp J, Dienstbier N, Borkhardt A, Bhatia S, Hansen FK.(JESS),cat. no. β-actin,Mouse,1:50,MAB8929 HSP90 total,Rabbit,1:100,CST#4877 HSP90α,Rabbit,1:100,CST#8165 HSP90β,Rabbit,1:100,CST#5087

(19) Long noncoding RNA Gm2694 drives depressive-like behaviors in male mice by interacting with GRP78 to disrupt endoplasmic reticulum homeostasisScience advancesDecember 2, 2022Chen HS, Wang J, Li HH, Wang X, Zhang SQ, Deng T, Li YK, Zou RS, Wang HJ, Zhu R, et al.from Abcam (Cambridge, MA, USA). Anti-IRE1α (#3294; 1:500), anti-GRP78 (#3183; 1:1000), anti-HSP90α (#8165; 1:1000), and anti-HSP90β (#7411; 1:1000) were obtained from Cell Signaling Technology (San Francisco,

(20) Hsp90 Inhibitor STA9090 induced VPS35 related extracellular vesicle release and metastasis in hepatocellular carcinomaTranslational oncologyDecember 1, 2022Tan W, Zhang J, Liu L, Liang M, Li J, Deng Z, Zheng Z, Deng Y, Liu C, Li Y, et al.Santa Cruz Biotechnology), HSF1 (sc-9144, Santa Cruz Biotechnology), Hsp70 (sc-69,705, Santa Cruz Biotechnology), Hsp90α (8165 s, Cell Signaling Technology), TSG101 (sc-7964, Santa Cruz Biotechnology), CD63 (25,682–1-AP, PROTEINTECH).

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HSP90alpha (D1A7) Rabbit mAb

HSP90alpha (D1A7) Rabbit mAb from Cell Signaling Technology

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Cell Signaling Technology

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HSP90alpha (D1A7) Rabbit mAb from Cell Signaling Technology

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