Polyoma virus middle T antigen (PyMT) Antibody sc-53481 from Santa Cruz Biotechnology, Inc.

Product Specs
ItemPolyoma virus middle T antigen (PyMT) Antibody
CompanySanta Cruz Biotechnology, Inc.
Price $316.00Supplier Page View Company Product Page
Catalog Numbersc-53481
Quantity200 µg/ml
ClonePyMT
Reactivitypolyoma virus
ApplicationsIP, IF
Conjugate/TagUnconjugated
Hostrat
FormatPurified
ClonalityMonoclonal
IsotypeIgG2b
TargetPolyoma virus middle T antigen
Antibody TypePrimary Antibodies

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Santa Cruz Biotechnology, Inc.

10410 Finnell Street

Dallas, Texas 75220

United States

Phone: 1-800-457-3801
831-457-3801

Company Profile

Website: http://www.scbt.com/

(1) The CHI3L1-neutrophil axis drives immune suppression and breast cancer metastatic disseminationJCI InsightMarch 23, 2026Tarek Taifour, Adéline Massé, Yu Gu, Virginie Sanguin-Gendreau, Dongmei Zuo, Bin Xiao, Emilie Solymoss, Yunyun Shen, Hailey Proud, Sherif Samer Attalla, et al.(BioLegend 127606), CD206 (BioLegend 141706), CD86 (BioLegend 105032), and PyMT (Santa Cruz Biotechnology sc-53481). Flow cytometry was done in the BD LSR Fortessa 4-laser (405/488/561/633 nm) flow cytometer, and the

(2) Loss of BPTF restores estrogen response and suppresses metastasis of mammary tumorsNat CommunOctober 15, 2025Michael F. Ciccone, Dhivyaa Anandan, Deeptiman Chatterjee, Chen Chen, Marygrace C. Trousdell, Rebecca Anderson, Steven M. Lewis, Mackenzie K. Callaway, Chris Z. Zhao, Amritha Varshini Hanasoge Somasundara, et al.dilution), Alexa Fluor 546 Polyoma virus middle T antigen Antibody (Santa Cruz Biotechnology, Cat# sc-53481; RRID: AB_630138) (1:50 dilution), N-cadherin (H-2) (Santa Cruz Biotechnology, Cat# sc-393933, RRID:AB_2832921)

(3) Modeling tumor relapse using proliferation tracing and ablation transgenic mouseNPJ Breast CancerJuly 17, 2025Chuang Zhao, Xin-Nan Zheng, Han-Ying Huang, Lin Tianin PBS with 0.5% Tween-20. Primary antibodies included: anti-PyMT (Alexa-647 conjugated, Santa Cruz, sc-53481) and anti-Ki67 (CST, #12202). Secondary antibodies included: Alexa-488 donkey anti-rabbit and Alexa-647

(4) Chronic circadian disruption modulates breast cancer stemness and immune microenvironment to drive metastasis in miceNature communicationsJune 24, 2020Hadadi E, Taylor W, Li XM, Aslan Y, Villote M, Rivière J, Duvallet G, Auriau C, Dulong S, Raymond-Letron I, et al.FBS/1% BSA/PBS for 24 h. Lungs were again rinsed with PBS, then incubated with anti-PyMT antibody (sc-53481, Santa Cruz, 1:100 dilution) for 48 h. Following overnight washing, lungs were incubated with rabbit

(5) Knockout model reveals the role of Nischarin in mammary gland development, breast tumorigenesis and response to metformin treatmentInternational journal of cancerMay 1, 2020Dong S, Ruiz-Calderon B, Rathinam R, Eastlack S, Maziveyi M, Alahari SK.

(6) Cellular Metabolic Heterogeneity In Vivo Is Recapitulated in Tumor OrganoidsNeoplasia (New York, N.Y.)June 1, 2019Sharick JT, Jeffery JJ, Karim MR, Walsh CM, Esbona K, Cook RS, Skala MC.

(7) A method of producing genetically manipulated mouse mammary glandBreast cancer research : BCRJanuary 5, 2019Tagaya H, Ishikawa K, Hosokawa Y, Kobayashi S, Ueoka Y, Shimada M, Ohashi Y, Mikami H, Yamamoto M, Ihara T, et al.

(8) Contributions of the RhoA guanine nucleotide exchange factor Net1 to polyoma middle T antigen-mediated mammary gland tumorigenesis and metastasisBreast cancer research : BCRMay 16, 2018Zuo Y, Ulu A, Chang JT, Frost JA.

(9) Identification of the tumour transition states occurring during EMTNatureApril 1, 2018Pastushenko I, Brisebarre A, Sifrim A, Fioramonti M, Revenco T, Boumahdi S, Van Keymeulen A, Brown D, Moers V, Lemaire S, et al.

(10) Angiopoietin-1 deficiency increases tumor metastasis in miceBMC cancerAugust 11, 2017Michael IP, Orebrand M, Lima M, Pereira B, Volpert O, Quaggin SE, Jeansson M.

(11) Cytosolic Hsp90α and its mitochondrial isoform Trap1 are differentially required in a breast cancer modelOncotargetMarch 14, 2017Vartholomaiou E, Madon-Simon M, Hagmann S, Mühlebach G, Wurst W, Floss T, Picard D.to H&E or immunohistochemical staining according to standard protocols using an anti-PyMT antibody (sc-53481; Santa Cruz Biotechnology). Histomorphometric analysis For measurements of total areas of lung metastasis,

(12) Lgr6 labels a rare population of mammary gland progenitor cells that are able to originate luminal mammary tumoursNature cell biologyDecember 1, 2016Blaas L, Pucci F, Messal HA, Andersson AB, Josue Ruiz E, Gerling M, Douagi I, Spencer-Dene B, Musch A, Mitter R, et al.(Abcam; Ab16667, 1:200), CD49f (BD Pharmingen, 555734, 1:100), anti-Middle T oncogene (Santa Cruz; sc-53481, 1:100). All secondary antibodies were biotinylated, horse radish peroxidase (HRP)-conjugated, or Alexa-conjugated

(13) Deletion of the BMP receptor BMPR1a impairs mammary tumor formation and metastasisOncotargetSeptember 8, 2015Pickup MW, Hover LD, Guo Y, Gorska AE, Chytil A, Novitskiy SV, Moses HL, Owens P.

(14) Modulation of tumor fatty acids, through overexpression or loss of thyroid hormone responsive protein spot 14 is associated with altered growth and metastasisBreast cancer research : BCRDecember 4, 2014Wellberg EA, Rudolph MC, Lewis AS, Padilla-Just N, Jedlicka P, Anderson SM.and anti-Actin (#5125) were obtained from Cell Signaling Technology (Beverly, MA, USA). Anti-PyMT (sc-53481), anti-Neu (sc-284), anti-FASN (sc-20140), anti-β-tubulin (sc-9104), and anti-Krt18 (sc-28264) were

(15) Expression of a phosphorylated substrate domain of p130Cas promotes PyMT-induced c-Src-dependent murine breast cancer progressionCarcinogenesisDecember 1, 2013Zhao Y, Kumbrink J, Lin BT, Bouton AH, Yang S, Toselli PA, Kirsch KH.

(16) The Huntington disease protein accelerates breast tumour development and metastasis through ErbB2/HER2 signallingEMBO molecular medicineFebruary 1, 2013Moreira Sousa C, McGuire JR, Thion MS, Gentien D, de la Grange P, Tezenas du Montcel S, Vincent-Salomon A, Durr A, Humbert S.ZO-1 (610966, BD Transduction Laboratories); vimentin (V6630, Sigma); α-tubulin (T6199, Sigma); PyVT (sc-53481, Santa Cruz); HER2 (Ab2428, Abcam); phospho-Akt (4058, Cell Signaling Technologies); Akt (9272, Cell Signaling Technologies

(17) Interactions between cancer stem cells and their niche govern metastatic colonizationNatureDecember 7, 2011Malanchi I, Santamaria-Martínez A, Susanto E, Peng H, Lehr HA, Delaloye JF, Huelsken J.

(18) Targeting intracellular oncoproteins with antibody therapy or vaccinationScience translational medicineSeptember 7, 2011Guo K, Li J, Tang JP, Tan CP, Hong CW, Al-Aidaroos AQ, Varghese L, Huang C, Zeng Q.

(19) Compensatory function of Pyk2 protein in the promotion of focal adhesion kinase (FAK)-null mammary cancer stem cell tumorigenicity and metastatic activityThe Journal of biological chemistryMay 27, 2011Fan H, Guan JL.

(20) Mice transgenic with SV40-late-promoter-driven Polyomavirus Middle T oncogene exclusively develop hemangiomasTransgenic researchJune 1, 2009Xu Q, Chen W, Wang Z, Zheng J, Zhang Z.

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Polyoma virus middle T antigen (PyMT) Antibody

Polyoma virus middle T antigen (PyMT) Antibody from Santa Cruz Biotechnology, Inc.

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Santa Cruz Biotechnology, Inc.

Citations (22)

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Polyoma virus middle T antigen (PyMT) Antibody from Santa Cruz Biotechnology, Inc.

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