WASP (D-1) Antibody sc-5300 from Santa Cruz Biotechnology, Inc.

Product Specs
ItemWASP (D-1) Antibody
CompanySanta Cruz Biotechnology, Inc.
Price $316.00Supplier Page View Company Product Page
Catalog Numbersc-5300
Antibody TypePrimary Antibodies
NCBI Gene AliasesIMD2, SCNX, THC, THC1, WASP, WASPA
Quantity200 µg/ml
ApplicationsWB, IP, IF, IHC(P), FCM, ELISA
Reactivityhuman
CloneD-1
FormatPurified
ClonalityMonoclonal
Conjugate/TagUnconjugated
Hostmouse
NCBI Full Gene NameWASP actin nucleation promoting factor
TargetWASP
IsotypeIgG1

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Santa Cruz Biotechnology, Inc.

10410 Finnell Street

Dallas, Texas 75220

United States

Phone: 1-800-457-3801
831-457-3801

Company Profile

Website: http://www.scbt.com/

(1) Actin nucleators safeguard replication forks by limiting nascent strand degradationNucleic acids researchJuly 7, 2023Nieminuszczy J, Martin PR, Broderick R, Krwawicz J, Kanellou A, Mocanu C, Bousgouni V, Smith C, Wen KK, Woodward BL, et al.(Bethyl Laboratories, A150-109A, 1:3000), (Biotin (Jackson Immunoresearch, 200-002-211, 1:1000), WASp (Santa Cruz, sc-5300, 1:500), N-WASp (Abcam, ab187527, 1:500), PCNA (Santa Cruz, sc-56, 1:500), PCNA (Abcam, ab18197, 1:500)

(2) Actin nucleators safeguard replication forks by limiting nascent strand degradationbioRxiv : the preprint server for biologyJanuary 12, 2023Nieminuszczy J, Martin PR, Broderick R, Krwawicz J, Kanellou A, Mocanu C, Bousgouni V, Smith C, Wen KK, Woodward BL, et al.

(3) Actin Retrograde Flow Regulated by the Wiskott-Aldrich Syndrome Protein Drives the Natural Killer Cell ResponseCancersAugust 2, 2022Sabag B, Levy M, Kivelevitz J, Dashevsky N, Ben-Shmuel A, Puthenveetil A, Awwad F, Barda-Saad M.Germany, Cat# sc-47724); and Mouse anti-WASp (D1) (Santa-Cruz Biotechnology, Heidelberg, Germany, Cat# sc-5300). Secondary Antibodies were: Goat anti-Rabbit (Santa Cruz Biotechnology, Heidelberg, Germany, Cat# sc-2004)

(4) Wiskott-Aldrich syndrome protein forms nuclear condensates and regulates alternative splicingNature communicationsJune 25, 2022Yuan B, Zhou X, Suzuki K, Ramos-Mandujano G, Wang M, Tehseen M, Cortés-Medina LV, Moresco JJ, Dunn S, Hernandez-Benitez R, et al.antibodies at 4 °C overnight. The primary antibodies, mouse monoclonal anti-WASP antibody (D-1) (Cat# SC-5300, Santa Cruz Biotechnology) and rabbit polyclonal isotype (Cat# ab37415, Abcam), were used as a negative

(5) Targeting the actin nucleation promoting factor WASp provides a therapeutic approach for hematopoietic malignanciesNature communicationsSeptember 22, 2021Biber G, Ben-Shmuel A, Noy E, Joseph N, Puthenveetil A, Reiss N, Levy O, Lazar I, Feiglin A, Ofran Y, et al.mouse anti-GFP 1:500 (Roche Applied Science—Catalogue no. 11 814 460 001), mouse anti-WASp D1 1:250 (sc-5300) and rabbit anti-GAPDH 1:1000 (Santa Cruz—sc-47724). HRP-conjugated goat anti-mouse 1:10,000 (Jackson—115-035-003)

(6) Nuclear ARP2/3 drives DNA break clustering for homology-directed repairNatureJuly 1, 2018Schrank BR, Aparicio T, Li Y, Chang W, Chait BT, Gundersen GG, Gottesman ME, Gautier J.antibodies include γH2AX (EMD Millipore: 05-636, 1/500 or Abcam: ab81299, 1/500), WASP (Santa Cruz: sc-5300, 1/50), Rad51 (Santa Cruz: sc-8349, 1/50), 53BP1 (Novus Biologicals: NC100-304, 1/250) and FLAG (Sigma Aldrich

(7) Gene therapy for Wiskott-Aldrich syndrome in a severely affected adultBloodSeptember 14, 2017Morris EC, Fox T, Chakraverty R, Tendeiro R, Snell K, Rivat C, Grace S, Gilmour K, Workman S, Buckland K, et al.

(8) Absence of WASp Enhances Hematopoietic and Megakaryocytic Differentiation in a Human Embryonic Stem Cell ModelMolecular therapy : the journal of the American Society of Gene TherapyFebruary 1, 2016Toscano MG, Muñoz P, Sánchez-Gilabert A, Cobo M, Benabdellah K, Anderson P, Ramos-Mejía V, Real PJ, Neth O, Molinos-Quintana A, et al.

(9) X-linked thrombocytopenia causing mutations in WASP (L46P and A47D) impair T cell chemotaxisJournal of biomedical scienceSeptember 9, 2014Jain N, Tan JH, Feng S, George B, Thanabalu T.

(10) Gene therapy for Wiskott-Aldrich syndrome--long-term efficacy and genotoxicityScience translational medicineMarch 12, 2014Braun CJ, Boztug K, Paruzynski A, Witzel M, Schwarzer A, Rothe M, Modlich U, Beier R, Göhring G, Steinemann D, et al.

(11) Loss of the F-BAR protein CIP4 reduces platelet production by impairing membrane-cytoskeleton remodelingBloodSeptember 5, 2013Chen Y, Aardema J, Kale S, Whichard ZL, Awomolo A, Blanchard E, Chang B, Myers DR, Ju L, Tran R, et al.

(12) Ubiquitylation-dependent negative regulation of WASp is essential for actin cytoskeleton dynamicsMolecular and cellular biologyAugust 1, 2012Reicher B, Joseph N, David A, Pauker MH, Perl O, Barda-Saad M.

(13) Foamy virus vector-mediated gene correction of a mouse model of Wiskott-Aldrich syndromeMolecular therapy : the journal of the American Society of Gene TherapyJune 1, 2012Uchiyama T, Adriani M, Jagadeesh GJ, Paine A, Candotti F.

(14) Mobilization of HIV spread by diaphanous 2 dependent filopodia in infected dendritic cellsPLoS pathogensJanuary 1, 2012Aggarwal A, Iemma TL, Shih I, Newsome TP, McAllery S, Cunningham AL, Turville SG.

(15) Development of novel efficient SIN vectors with improved safety features for Wiskott-Aldrich syndrome stem cell based gene therapyMolecular pharmaceuticsOctober 3, 2011Avedillo Díez I, Zychlinski D, Coci EG, Galla M, Modlich U, Dewey RA, Schwarzer A, Maetzig T, Mpofu N, Jaeckel E, et al.

(16) A novel WASP gene mutation in a Chinese boy with Wiskott-Aldrich syndromeInternational journal of hematologySeptember 1, 2010Yu H, Liu T, Meng W, Hou L.

(17) Clinical aspects and genetic analysis of taiwanese patients with wiskott-Aldrich syndrome protein mutation: the first identification of x-linked thrombocytopenia in the chinese with novel mutationsJournal of clinical immunologyJuly 1, 2010Lee WI, Huang JL, Jaing TH, Wu KH, Chien YH, Chang KW.

(18) Impaired NK-cell migration in WAS/XLT patients: role of Cdc42/WASp pathway in the control of chemokine-induced beta2 integrin high-affinity stateBloodApril 8, 2010Stabile H, Carlino C, Mazza C, Giliani S, Morrone S, Notarangelo LD, Notarangelo LD, Santoni A, Gismondi A.

(19) Revertant T lymphocytes in a patient with Wiskott-Aldrich syndrome: analysis of function and distribution in lymphoid organsThe Journal of allergy and clinical immunologyFebruary 1, 2010Trifari S, Scaramuzza S, Catucci M, Ponzoni M, Mollica L, Chiesa R, Cattaneo F, Lafouresse F, Calvez R, Vermi W, et al.

(20) Improved lentiviral vectors for Wiskott-Aldrich syndrome gene therapy mimic endogenous expression profiles throughout haematopoiesisGene therapyJune 1, 2008Frecha C, Toscano MG, Costa C, Saez-Lara MJ, Cosset FL, Verhoeyen E, Martin F.

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WASP (D-1) Antibody

WASP (D-1) Antibody from Santa Cruz Biotechnology, Inc.

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Santa Cruz Biotechnology, Inc.

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WASP (D-1) Antibody from Santa Cruz Biotechnology, Inc.

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