PR (AB-52) Antibody sc-810 from Santa Cruz Biotechnology, Inc.

Product Specs
ItemPR (AB-52) Antibody
CompanySanta Cruz Biotechnology, Inc.
Price $316.00Supplier Page View Company Product Page
Catalog Numbersc-810
Antibody TypePrimary Antibodies
NCBI Gene AliasesNR3C3, 9930019P03Rik, PR, PR-A, PR-B
Quantity200 µg/ml
ApplicationsWB, IP, IF, IHC(P)
CloneAB-52
Reactivitymouse, rat, human
Conjugate/TagUnconjugated
ClonalityMonoclonal
Hostmouse
FormatPurified
NCBI Full Gene Nameprogesterone receptor
TargetPR
IsotypeIgG1

Questions and Answers

Can this antibody be used for immunohistochemistry in ovarian cancer research?

Yes, the PR (AB-52) antibody has been utilized in immunohistochemistry to study progesterone receptor expression in ovarian cancer cells, as demonstrated in research where it was used to evaluate the effects of progesterone on cell death in PR-negative ovarian cancer cell lines ().

What is the significance of using this antibody in studies related to breast cancer?

The PR (AB-52) antibody has been shown to play a role in breast cancer research, particularly in studies examining the interaction between progesterone and other therapeutic agents like trastuzumab. It has been used to investigate how progesterone can interfere with the inhibitory effects of trastuzumab on cell viability in triple-positive breast cancer cells ().

Is this antibody effective for detecting progesterone receptors in Western blotting applications?

Yes, the PR (AB-52) antibody has been effectively used in Western blotting to detect both PR-A and PR-B isoforms in various studies, confirming its utility in analyzing progesterone receptor expression in different tissue types (, ).

What species does this antibody react with, and how has it been validated in research?

The PR (AB-52) antibody is reactive with mouse, human, and rat tissues. It has been cited in numerous studies, including those examining its role in modulating pain perception through progesterone receptor signaling in animal models ().

Santa Cruz Biotechnology, Inc.

10410 Finnell Street

Dallas, Texas 75220

United States

Phone: 1-800-457-3801
831-457-3801

Company Profile

Website: http://www.scbt.com/

(1) Synthetic estrogen and progestin effects on the myogenic program following damage in C2C12 murine myoblastsPhysiol RepApril 26, 2026Mai Wageh, Michael Kamal, Gianni Parise2007; Wiik et al., 2005); and ERβ (sc‐53,494) (Guo et al., 2010; Lee et al., 2021); 1:500 for PRα/β (sc‐810) (Pieber et al., 2001; Shanmugam et al., 2023); and 1:100 for Myogenin (sc‐12,732); purchased from Santa Cruz Biotechnology

(2) Chemerin's Role in Endometrial Dysfunction: Insights From Transcriptomic AnalysisJ Cell Mol MedMarch 21, 2025Ming Yu, Yichun Wang, Jinxuan Cai, Xinyue Dong, Hao Wang, Zichen Sun, Tianxia Xiao, Jie Chen, Mengxia Li, Chunhua Shan, et al.primary antibody: anti‐Progesterone receptor (Santa Cruz Biotechnology, Dallas, Texas, USA, Catalogue #: sc‐810, 1/500), anti‐Oestrogen Receptor alpha (Santa Cruz Biotechnology, Catalogue #: sc‐8005, 1/500), anti‐Oestrogen

(3) SHP2 is essential for the progesterone-promoted proliferation and migration in breast cancer cell linesFront Endocrinol (Lausanne)February 10, 2025Hui-Chen Wang, Wen-Sen Leepurchased from GIBCO (Grand Island, NY). P4 was obtained from Sigma-Aldrich (St. Louis, MO); Anti-PR (sc-810) antibody was from Santa Cruz Biotechnology, Inc. (Santa Cruz, CA). Anti-cSrc (#2109), anti-p-cSrcY416

(4) UBX-390: A Novel Androgen Receptor Degrader for Therapeutic Intervention in Prostate CancerAdvanced science (Weinheim, Baden-Wurttemberg, Germany)September 1, 2024Lee S, Kim HR, Woo Y, Kim J, Kim HW, Park JY, Suh B, Choi Y, Ahn J, Ryu JH, et al.for immunoblotting: GR (A303‐490A) and ELL2 (A302505A) from Bethyl Laboratories (Montgomery, TX, USA); PR (sc‐810), VHL (sc‐17780), PCLAF (sc‐390515), and hemagglutinin‐tag (sc‐7392) from Santa Cruz Biotechnology (Dallas,

(5) Progestogen-driven B7-H4 contributes to onco-fetal immune toleranceCellAugust 22, 2024Jiali Yu, Yijian Yan, Shasha Li, Ying Xu, Abhijit Parolia, Syed Rizvi, Weichao Wang, Yiwen Zhai, Rongxin Xiao, Xiong Li, et al.AB_330288 GAPDH,Cell Signaling Technology,Cat#97166; RRID: AB_627678 Anti-mouse Progesterone receptor,Santa Cruz,Cat#sc-810; RRID: AB_628172 Anti-human Progesterone receptor,Cell Signaling Technology,Cat#8757s; RRID: AB_2797144 "Chemicals,

(6) Morphology, Glycan Pattern, Heat Shock Proteins, and Sex Steroid Receptors Expression in the Tubal Fimbria Epithelium of the Baboon Papio hamadryas during the Menstrual CycleAnimals (Basel)August 11, 2024Salvatore Desantis, Mario Cinone, Luca Lacitignola, Pietro Laricchiuta, Roberta Rossi, Antonio Ciro Guaricci, Leonardo Resta, Maria Albrizio(AB-52),mouse monoclonal,native human PR-A and PR-B,1:50,"Santa Cruz Biotechnology, Inc., Santa Cruz, CA, USA",sc-810 The primary antibodies used for immunohistochemical detection of ER, PR, HSP 60,70,90 in the fimbriae

(7) Bushen Antai recipe ameliorates immune microenvironment and maternal-fetal vascularization in STAT3-deficient abortion-prone miceJournal of ethnopharmacologyJanuary 10, 2024Liu Z, Song Y, Hu R, Geng Y, Huang Y, Li F, Ma W, Dong H, Song K, Ding J, et al.

(8) The role of non‐genomic actions of progesterone and its membrane receptor agonist in ovarian cancer cell deathCancer Rep (Hoboken)January 1, 2024Takahiro Koyanagi, Yasushi Saga, Yoshifumi Takahashi, Kohei Tamura, Takahiro Yoshiba, Suzuyo Takahashi, Akiyo Taneichi, Yuji Takei, Hiroaki Mizukami, Hiroyuki FujiwaraImmunoreaction Enhance Solution 1 (Toyobo Life Science): Anti‐PR mouse monoclonal antibody (cat. no. sc‐810; 1:100; Santa Cruz Biotechnology, Inc., Dallas, TX, USA) and anti‐BAX (D2E11) rabbit monoclonal antibody

(9) The inhibitory effect of trastuzumab on BT474 triple‑positive breast cancer cell viability is reversed by the combination of progesterone and estradiolOncology LettersNovember 15, 2023José A. López‑Méndez, José L. Ventura‑Gallegos, Ignacio Camacho‑Arroyo, Marcela Lizano, Alberto J. Cabrera‑Quintero, Sandra L. Romero‑Córdoba, Mariano Martínez‑Vázquez, Nadia J. Jacobo‑Herrera, Alfonso León‑Del‑Río, Adrian A. Paredes‑Villa, et al.overnight in 0.1% bovine serum albumin (cat. no. 160069; MP Biomedicals) at 4°C: PRA/B (1:500; cat. no. sc-810; Santa Cruz Biotechnology, Inc.), ER (1:500; cat. no. sc-8005; Santa Cruz Biotechnology, Inc.), Akt

(10) Progesterone distribution in the trigeminal system and its role to modulate sensory neurotransmission: influence of sexThe journal of headache and painNovember 14, 2023Maddahi A, Warfvinge K, Holm A, Edvinsson JCA, Reducha PV, Kazantzi S, Haanes KA, Edvinsson L.(MA1-411),1:50,Mouse,"Progesterone receptor, detection of PR-B","Thermo Fisher Scientific,USA" "Progesterone receptor,SC-810",1:50,Mouse,"Human progesterone receptor, detection of PR-A and PR-B","Santa Cruz Biotechnology, Germany" CGRP(ab81887),1:100,Mouse,Rat

(11) TRPS1 regulates the opposite effect of progesterone via RANKL in endometrial carcinoma and breast carcinomaCell death discoveryJune 21, 2023Yang L, Fan Q, Wang J, Yang X, Yuan J, Li Y, Sun X, Wang Y.[74]. The cells were fixed, permeabilized and blocked, then primary antibodies against PR (Santa Cruz, sc-810) and TRPS1 (Sigma Aldrich, HPA060380) were incubated with cells overnight at 4 °C, respectively, followed

(12) Injectable self-assembled dual-crosslinked alginate/recombinant collagen-based hydrogel for endometrium regenerationInternational journal of biological macromoleculesMay 1, 2023Fang Z, Lu C, Du W, Wang X, Yang H, Shi M, Liu T, Xie Y, Wang S, Xu X, et al.

(13) Development of cell-laden multimodular Lego-like customizable endometrial tissue assembly for successful tissue regenerationBiomaterials researchApril 21, 2023Park SR, Kook MG, Kim SR, Lee JW, Park CH, Oh BC, Jung Y, Hong IS.(Santa cruz biotechnology, Cat. No.: sc-8005), progesterone receptor (Santa cruz biotechnology, Cat. No.: sc-810), vimentin (BD biosciences, Cat. No.: 550,513), cytokeratin 14 (Santa cruz biotechnology, Cat. No.:

(14) Activation of progesterone receptor is essential for folic acid-regulated cancer cell proliferation and migrationThe Journal of nutritional biochemistryFebruary 1, 2023Wang HC, Huo YN, Lee WS.

(15) Maternal exposure to di(2-ethylhexyl) phthalate (DEHP) causes multigenerational adverse effects on the uterus of F(1) and F(2) offspring ratsReproductive toxicology (Elmsford, N.Y.)January 1, 2023Shanmugam DAS, Dhatchanamurthy S, Leela KA, Bhaskaran RS.

(16) Profiling estrogen, progesterone, and androgen receptors in colorectal cancer in relation to gender, menopausal status, clinical stage, and tumour sidednessFrontiers in endocrinologyJanuary 1, 2023Refaat B, Aslam A, Idris S, Almalki AH, Alkhaldi MY, Asiri HA, Almaimani RA, Mujalli A, Minshawi F, Alamri SA, et al.(Santa-Cruz Biotechnology Inc.; CA, USA) were used to detect ERα (#sc-8002), ERβ (#sc-53494), PGR (#sc-810), and AR (#sc-7305) in 5-μm sections from each non-malignant and cancerous tissues. Endogenous peroxidases

(17) Fibroblast growth factor 1 ameliorates thin endometrium in rats through activation of the autophagic pathwayFrontiers in pharmacologyJanuary 1, 2023Zhu J, Li Z, Yin F, Yu X, Lu Y, Zhou T, Gong F, Xu Z.anti-estrogen receptor (ER; 1:100; 21244-1-AP; Proteintech Group, Inc.), anti-progesterone receptor (PR; 1:100; sc-810; Santa Cruz Biotechnology, Inc.) and anti-cytokeratin 19 (CK19; 1:200; 10712-1-AP; Proteintech Group, Inc

(18) Progesterone Receptor Modulates Extraembryonic Mesoderm and Cardiac Progenitor Specification during Mouse GastrulationInternational journal of molecular sciencesSeptember 7, 2022Drozd AM, Mariani L, Guo X, Goitea V, Menezes NA, Ferretti E.solution (1% BSA in 0.1% Triton/PBS with antibodies) containing mouse anti-PGR (Santa Cruz Biotechnology, sc-810, Dallas, TX, USA) overnight at 4 °C. The following day, we washed cells 3 × 5 min using washing solution

(19) Bortezomib-Induced Ovarian Toxicity in MiceToxicologic pathologyApril 1, 2022Mutluay D, Tenekeci GY, Monsef YA.

(20) 3D stem cell-laden artificial endometrium: successful endometrial regeneration and pregnancyBiofabricationAugust 16, 2021Park SR, Kim SR, Im JB, Park CH, Lee HY, Hong IS.

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PR (AB-52) Antibody

PR (AB-52) Antibody from Santa Cruz Biotechnology, Inc.

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Santa Cruz Biotechnology, Inc.

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PR (AB-52) Antibody from Santa Cruz Biotechnology, Inc.

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