c-Fms/CSF-1R (B-8) Antibody sc-46662 from Santa Cruz Biotechnology, Inc.

Product Specs
Itemc-Fms/CSF-1R (B-8) Antibody
CompanySanta Cruz Biotechnology, Inc.
Price $316.00Supplier Page View Company Product Page
Catalog Numbersc-46662
Antibody TypePrimary Antibodies
NCBI Gene AliasesFIM2, HDLS1, Csfmr, CD115, M-CSFR, M-CSF-R, FMS, CSFR, C-FMS, GPSC, Fms, BANDDOS, Fim-2, Fim2, CSF-1R, HDLS
CloneB-8
Quantity200 µg/ml
ApplicationsWB, IP, IF, IHC(P), ELISA
Reactivitymouse, rat, human
FormatPurified
Hostmouse
ClonalityMonoclonal
Conjugate/TagUnconjugated
NCBI Full Gene Namecolony stimulating factor 1 receptor
Targetc-Fms/CSF-1R
IsotypeIgG1

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Santa Cruz Biotechnology, Inc.

10410 Finnell Street

Dallas, Texas 75220

United States

Phone: 1-800-457-3801
831-457-3801

Company Profile

Website: http://www.scbt.com/

(1) Non-invasive assessment of activated renal macrophages by imaging of colony-stimulating factor 1 receptor in mouse model with ischemic acute kidney injuryJournal of InflammationNovember 25, 2025Sijun Chen, Xinran Zhao, Yanshan Li, Nailian Zhang, Xiyan Rui, Xuejing Guan, Fangfei Hu, Chie Seki, Lin Xie, Ming-Rong Zhang, et al.A3-1; rat monoclonal, 1:1000; Abcam, ab6640), anti-CSF1R (B-8; mouse monoclonal, 1:1000; Santa Cruz, sc-46662), anti-KIM-1/HAVCR1 (rabbit polyclonal, 1:200; Proteintech, 30948-1-AP) and anti-CD206 antibody (rabbit

(2) Evaluation of in vivo and in vitro binding property of a novel candidate PET tracer for CSF1R imaging and comparison with two currently-used CSF1R-PET tracersEJNMMI Radiopharm ChemMay 13, 2025Xiyan Rui, Yuzhou Ding, Nailian Zhang, Xinran Zhao, Chie Seki, Tomoteru Yamasaki, Masayuki Fujinaga, Ming-Rong Zhang, Jun Qian, Bin Ji, et al.performed according to a standard protocol, with a mouse monoclonal anti-CSF1R antibody (1:500; SANTA CRUZ, sc-46662) as the primary antibody and a fluorophore-conjugated secondary antibody (1:500; goat anti-mouse IgG;

(3) Staphylococcus Aureus Tames Nociceptive Neurons to Suppress Synovial Macrophage Responses for Sustained Infection in Septic ArthritisAdvanced ScienceFebruary 17, 2025Xinyu Fang, Yang Chen, Haiqi Ding, Changyu Huang, Hongxin Hu, Chaofan Zhang, Yunzhi Lin, Qijin Wang, Xueni Hu, Yiming Lin, et al.sc‐377227, 1:200), rabbit anti‐CX3CR1 (Invitrogen, 702 321, 1:250), and mouse anti‐CSF1R (Santa Cruz, sc‐46662, 1:200). After rinsing with PBS (5 × 5 min), the sections were incubated for 2 h at room temperature

(4) miR-449, identified through antiandrogen exposure, mitigates functional biomarkers associated with ovarian cancer riskScientific ReportsDecember 2, 2024Xia Wang, Ho-Hyung Woo, Michelle Wei, Steven Gibson, Mitzi Miranda, Demaretta Rush, Janiel Cragun, Wenxin Zheng, Guang Yao, Setsuko K. Chamberselectroblotted onto a PVDF membrane. The membranes were incubated with mouse monoclonal anti-c-fms (sc-46662, Santa Cruz Biotech, USA), anti-AR (sc-7305, Santa Cruz Biotech, USA), and anti-Pan Actin (ACTN05, NeoMarkers,

(5) Effects of trans-(±)-kusunokinin on chemosensitive and chemoresistant ovarian cancer cellsOncology lettersFebruary 1, 2022Mad-Adam N, Rattanaburee T, Tanawattanasuntorn T, Graidist P.cat. no. 4976; Cell Signaling Technology, Inc.), CSF1R (1:500; mouse monoclonal antibody; cat. no. sc-46662; Santa Cruz Technology, Inc.) and GAPDH (internal control; 1:5,000; mouse monoclonal antibody, cat.

(6) Identification of Hub Genes and Therapeutic Agents for IgA Nephropathy Through Bioinformatics Analysis and Experimental ValidationFrontiers in medicineJanuary 1, 2022Xia M, Liu D, Liu H, Peng L, Yang D, Tang C, Chen G, Liu Y, Liu H.(Santa Cruz Biotechnology, sc-390222), and colony-stimulating factor 1 receptor (CSF1R) (Santa Cruz Biotechnology, sc-46662), periodic acid-Schiff (PAS) was used instead of primary antibodies as negative controls for all staining.

(7) Ly6c as a New Marker of Mouse Blood Vessels: Qualitative and Quantitative Analyses on Intact and Ischemic RetinasInternational journal of molecular sciencesDecember 21, 2021Martínez-Carmona M, Lucas-Ruiz F, Gallego-Ortega A, Galindo-Romero C, Norte-Muñoz M, González-Riquelme MJ, Valiente-Soriano FJ, Vidal-Sanz M, Agudo-Barriuso M.(1:500; sc-52650, Santa Cruz Biotechnology Inc., Dallas, TX, USA) and mouse monoclonal α-CD115 (1:200; sc-46662, Santa Cruz Biotechnology Inc., Dallas, TX, USA). Secondary detection was carried out with goat α-rat

(8) Clinical and genetic characterization of adult-onset leukoencephalopathy caused by CSF1R mutationsAnnals of clinical and translational neurologyNovember 1, 2021Tsai PC, Fuh JL, Yang CC, Chang A, Lien LM, Wang PN, Lai KL, Tsai YS, Lee YC, Liao YC.treatment were used as controls. Total CSF1R expression levels were analyzed using the CSF1R antibody (sc‐46662; Santa Cruz, Dallas, TX). CSF1R autophosphorylation ability was evaluated using CSF1R phospho‐tyrosine

(9) Proteolytic Shedding of Human Colony-Stimulating Factor 1 Receptor and its implicationJournal of cellular and molecular medicineMay 1, 2021Wei Y, Ma M, Lin S, Li X, Shu Y, Wang Z, Zhou Y, Hu B, Cheng B, Duan S, et al.

(10) Identification of Three Significant Genes Associated with Immune Cells Infiltration in Dysfunctional Adipose Tissue-Induced Insulin-Resistance of Obese Patients via Comprehensive Bioinformatics AnalysisInternational journal of endocrinologyJanuary 1, 2021Zhai M, Luan P, Shi Y, Li B, Kang J, Hu F, Li M, Du L, Zhou D, Jian W, et al.processed, and paraﬃn embedded for sectioning into 3-mm thick sections. Immunohistochemical tests for CSF1R (sc-46662; Santa Cruz Biotechnology, USA), C1QC (ab75756; Abcam, UK), and CD68 (NBP233337, Novus Biologicals,

(11) Schwann cells orchestrate peripheral nerve inflammation through the expression of CSF1, IL-34, and SCF in amyotrophic lateral sclerosisGliaJune 1, 2020Trias E, Kovacs M, King PH, Si Y, Kwon Y, Varela V, Ibarburu S, Moura IC, Hermine O, Beckman JS, et al.(Santa Cruz Biotechnology, #sc-692), 1:200 mouse monoclonal anti-CSF-1R (Santa Cruz Biotechnology, #sc-46662), 1:250 mouse monoclonal anti-CD68 (abcam, #ab31630), 1:300 Isolectin-Biotin probe (Thermo Fisher Scientific,

(12) Dynamic gene regulation by nuclear colony-stimulating factor 1 receptor in human monocytes and macrophagesNature communicationsApril 26, 2019Bencheikh L, Diop MK, Rivière J, Imanci A, Pierron G, Souquere S, Naimo A, Morabito M, Dussiot M, De Leeuw F, et al.Santa Cruz Biotechnology. For ChIP-qPCR and ChIP-seq experiments we used two anti-CSF-1R antibodies (sc-692 and sc-46662), EGR1 antibody (sc-110X), corresponding isotype controls (normal rabbit IgG sc-2027, normal mouse IgG

(13) Colony‑stimulating factor 1 receptor inhibition blocks macrophage infiltration and endometrial cancer cell proliferationMolecular medicine reportsApril 1, 2019Hua F, Tian Y, Gao Y, Li C, Liu X.with 4% paraformaldehyde for 15 min at room temperature. Primary mouse CSF-1R monoclonal antibody (sc46662, Santa Cruz Biotechnology, Inc., Dallas, TX, USA; 1:100) were revealed with specific goat anti-mouse

(14) Alcohol enhances type 1 interferon-α production and mortality in young mice infected with Mycobacterium tuberculosisPLoS pathogensAugust 1, 2018Tripathi D, Welch E, Cheekatla SS, Radhakrishnan RK, Venkatasubramanian S, Paidipally P, Van A, Samten B, Devalraju KP, Neela VSK, et al.sc-58965), anti-Ly6C (Santa Cruz Biotechnology, INC; sc-52650), anti-CD115 (Santa Cruz Biotechnology, INC; sc-46662), anti-CD200 (Santa Cruz Biotechnology, INC; sc-53100), anti-CD11c (Abcam; ab33483), anti-CD68 (Abcam; ab53444),

(15) The RUNX1/IL-34/CSF-1R axis is an autocrinally regulated modulator of resistance to BRAF-V600E inhibition in melanomaJCI insightJuly 26, 2018Giricz O, Mo Y, Dahlman KB, Cotto-Rios XM, Vardabasso C, Nguyen H, Matusow B, Bartenstein M, Polishchuk V, Johnson DB, et al.Phospho-Akt (Ser473, catalog 9271), and AKT (catalog 9272) (from Cell Signaling Technologies) or CSF-1R (sc-46662) and Actin HRP (catalog sc-1615) (catalog Santa Cruz Biotechnologies Inc.) as loading control. Primary

(16) Evidence for mast cells contributing to neuromuscular pathology in an inherited model of ALSJCI insightOctober 19, 2017Trias E, Ibarburu S, Barreto-Núñez R, Varela V, Moura IC, Dubreuil P, Hermine O, Beckman JS, Barbeito L.anti-S100β (MilliporeSigma, S2532), 1:250 mouse monoclonal anti–CSF1R (Santa Cruz Biotechnology Inc., sc-46662), 1:300 rabbit polyclonal anti-Iba1 (Wako, 019-19741), 1:250 mouse monoclonal anti-CD68 (Abcam, ab31630),

(17) Chromatin-associated CSF-1R binds to the promoter of proliferation-related genes in breast cancer cellsOncogeneAugust 21, 2014Barbetti V, Morandi A, Tusa I, Digiacomo G, Riverso M, Marzi I, Cipolleschi MG, Bessi S, Giannini A, Di Leo A, et al.a-C-terminal-CSF-1R (Ct-CSF-1R; 0.4 mg per sample), mouse a-N-terminal-CSF-1R (Nt-CSF-1R; B-8, Santa Cruz, number sc-46662, 4 mg per sample), control rabbit IgG (rIgG; 0.4 mg per sample, Sigma number G5518), control mouse IgG

(18) Haploinsufficiency of CSF-1R and clinicopathologic characterization in patients with HDLSNeurologyJanuary 14, 2014Konno T, Tada M, Tada M, Koyama A, Nozaki H, Harigaya Y, Nishimiya J, Matsunaga A, Yoshikura N, Ishihara K, et al.

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c-Fms/CSF-1R (B-8) Antibody

c-Fms/CSF-1R (B-8) Antibody from Santa Cruz Biotechnology, Inc.

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Santa Cruz Biotechnology, Inc.

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c-Fms/CSF-1R (B-8) Antibody from Santa Cruz Biotechnology, Inc.

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