ORC6 (3A4) Antibody sc-32735 from Santa Cruz Biotechnology, Inc.

Product Specs
ItemORC6 (3A4) Antibody
CompanySanta Cruz Biotechnology, Inc.
Price $316.00Supplier Page View Company Product Page
Catalog Numbersc-32735
NCBI Gene AliasesORC6L, 6720420I10Rik, Orc6l
Antibody TypePrimary Antibodies
Quantity200 µg/ml
Clone3A4
ApplicationsWB, IP, IF, IHC(P)
Reactivitymouse, rat, human
Hostrat
FormatPurified
Conjugate/TagUnconjugated
ClonalityMonoclonal
NCBI Full Gene Nameorigin recognition complex subunit 6, origin recognition complex, subunit 6
TargetORC6
IsotypeIgG2a

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Santa Cruz Biotechnology, Inc.

10410 Finnell Street

Dallas, Texas 75220

United States

Phone: 1-800-457-3801
831-457-3801

Company Profile

Website: http://www.scbt.com/

(1) Topoisomerase I Inhibition in ETV4-overexpressed Non-Small Cell Lung Cancer Promotes Replication and Transcription Mediated R-Loop Accumulation and DNA DamageAdvanced science (Weinheim, Baden-Wurttemberg, Germany)September 1, 2025Zhang J, Wang Y, Cao S, Xie SM, Liu B, Li Y, Hou Y, Meng X, Ruan M, Bu D, et al.for exogenous ETV4 detection, ETV4 antibody (sc‐113x, Santa Cruz), ORC1 (NBP100‐121, Novus), ORC6 (sc‐32735, Santa Cruz) for endogenous detection, or IgG (2729, CST) as a control. After the cross‐links are reversed,

(2) TERRA transcription destabilizes telomere integrity to initiate break-induced replication in human ALT cellsNature communicationsJune 18, 2021Silva B, Arora R, Bione S, Azzalin CM.(Santa Cruz Biotechnology, sc-398734; 1:500), a rat monoclonal anti-ORC6 (Santa Cruz Biotechnology, sc-32735; 1:500), a rabbit monoclonal anti-LIG4 (Abcam, ab193353; 1:2000). Secondary antibodies were HRP-conjugated

(3) CDK12 controls G1/S progression by regulating RNAPII processivity at core DNA replication genesEMBO reportsSeptember 1, 2019Chirackal Manavalan AP, Pilarova K, Kluge M, Bartholomeeusen K, Rajecky M, Oppelt J, Khirsariya P, Paruch K, Krejci L, Friedel CC, et al.,Santa Cruz FUS,4H11,sc‐47711,–,–,"1:10,000",Santa Cruz Histone 2A (H2A),,ab18255,–,–,"1:10,000",Abcam ORC6,3A4,sc‐32735,–,–,"1:3,000",Santa Cruz E2F1,,A300‐766A,5 μg,–,–,Bethyl E2F3,PG30,sc‐56665,5 μg,–,–,Santa Cruz CDK12,U1‐4th

(4) Rapid DNA replication origin licensing protects stem cell pluripotencyeLifeNovember 17, 2017Matson JP, Dumitru R, Coryell P, Baxley RM, Chen W, Twaroski K, Webber BR, Tolar J, Bielinsky AK, Purvis JE, et al.(Santa Cruz Biotechnology, Cat#sc-198), Orc1, (Bethyl Laboratories, Cat#A301-892A), Orc6, (Santa Cruz Biotechnology, Cat#sc-32735), geminin, (Santa Cruz Biotechnology, Cat#sc-13015), Histone H3, (Cell Signaling Technologies, Cat#4499S),

(5) The presence of extra chromosomes leads to genomic instabilityNature communicationsFebruary 15, 2016Passerini V, Ozeri-Galai E, de Pagter MS, Donnelly N, Schmalbrock S, Kloosterman WP, Kerem B, Storchová Z.A301-244A), RPA1 (1:1,000; Abcam ab79398), CDC6 (1:1,000; Santa Cruz sc-9964), ORC6 (1:1,000, Santa Cruz sc-32735), ORC2 (1:1,000, Santa Cruz sc-32734), RFC4 (1:1,000; Santa Cruz sc-20996), RFC5 (1:1,000; Bethyl A300-146A),

(6) A Role of hIPI3 in DNA Replication Licensing in Human CellsPloS oneJanuary 1, 2016Huang Y, Amin A, Qin Y, Wang Z, Jiang H, Liang L, Shi L, Liang C.anti-Mcm7 (Santa Cruz, sc-9966, 1:1,000), anti-Cdc6 (Santa Cruz, sc-9964, 1:1,500), anti-Orc6 (Santa Cruz, sc-32735, 1:1,500), anti-β-actin (Sigma, A2228, 1:1,000), or anti-HA (Roche, 12CA5, 1:20,000). The signals were

(7) Ku protein levels, localization and association to replication origins in different stages of breast tumor progressionJournal of CancerJanuary 1, 2013Abdelbaqi K, Di Paola D, Rampakakis E, Zannis-Hadjopoulos M.anti-Orc2 (sc-32734), anti-Orc3 (sc-21862), anti-Orc4 (sc-20634), anti-Orc5 (sc-19728), anti-Orc6 (sc-32735), anti-MCM7 (sc-46687), anti-DNA-PKcs (sc-9051), anti-α Tubulin (sc-8035) (Santa Cruz Biotechnology,

(8) Epstein-Barr nuclear antigen 1 (EBNA1)-dependent recruitment of origin recognition complex (Orc) on oriP of Epstein-Barr virus with purified proteins: stimulation by Cdc6 through its direct interaction with EBNA1The Journal of biological chemistryJuly 6, 2012Moriyama K, Yoshizawa-Sugata N, Obuse C, Tsurimoto T, Masai H.

(9) Recruitment of the human Cdt1 replication licensing protein by the loop domain of Hec1 is required for stable kinetochore-microtubule attachmentNature cell biologyMay 13, 2012Varma D, Chandrasekaran S, Sundin LJ, Reidy KT, Wan X, Chasse DA, Nevis KR, DeLuca JG, Salmon ED, Cook JG.of Bruce Stillman; anti-Orc6 for immunoblots (1:1000) was purchased from Santa Cruz Biotechnology (# sc-32735, clone [3A4]). Immunoblots were scanned into Adobe Photoshop and any manipulations for brightness were

(10) Comparative analysis of pre-replication complex proteins in transformed and normal cellsJournal of cellular biochemistryApril 1, 2012Di Paola D, Zannis-Hadjopoulos M.

(11) Ku is involved in cell growth, DNA replication and G1-S transitionJournal of cell scienceMarch 1, 2008Rampakakis E, Di Paola D, Zannis-Hadjopoulos M.

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ORC6 (3A4) Antibody

ORC6 (3A4) Antibody from Santa Cruz Biotechnology, Inc.

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Santa Cruz Biotechnology, Inc.

Citations (11)

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ORC6 (3A4) Antibody from Santa Cruz Biotechnology, Inc.

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