Description
Product Characteristics:
Synonyms: CD32, FCG2, FcGR, CD32A, CDw32, FCGR2, IGFR2, FCGR2A1, Low affinity immunoglobulin gamma Fc region receptor II-a, IgG Fc receptor II-a, Fc-gamma RII-a, Fc-gamma-RIIa, FcRII-a, FCGR2A
Target Information: The protein encoded by this gene is a low affinity receptor for the Fc region of immunoglobulin gamma complexes. The encoded protein is involved in the phagocytosis of immune complexes and in the regulation of antibody production by B-cells. Variations in this gene may increase susceptibilty to systemic lupus erythematosus (SLE). Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2010]