pan ECA (MECA-32) Antibody sc-19603 from Santa Cruz Biotechnology, Inc.

Product Specs
Itempan ECA (MECA-32) Antibody
CompanySanta Cruz Biotechnology, Inc.
Price $316.00Supplier Page View Company Product Page
Catalog Numbersc-19603
Quantity200 µg/ml
ApplicationsIP, IF, FCM
CloneMECA-32
Reactivitymouse
FormatPurified
Hostrat
ClonalityMonoclonal
Conjugate/TagUnconjugated
Targetpan ECA
IsotypeIgG2a
NCBI Full Gene Nameplasmalemma vesicle associated protein
NCBI Gene AliasesPv1, MECA32
Antibody TypePrimary Antibodies

Questions and Answers

Can this antibody be used for immunofluorescence applications in mouse tissues?

Yes, the pan ECA (MECA-32) antibody has been shown to be effective for immunofluorescence applications in mouse tissues, as demonstrated in studies where it was utilized to stain endothelial cells in tissue sections from mice ().

What specific role does this antibody play in studying endothelial cells?

The pan ECA (MECA-32) antibody targets the PLVAP protein, which is crucial for endothelial cell function. It has been used to investigate the interactions between endothelial cells and macrophages, highlighting the role of endothelial cells in macrophage differentiation and polarization towards an M2-like phenotype ().

Is this antibody suitable for flow cytometry applications?

Yes, the pan ECA (MECA-32) antibody is suitable for flow cytometry applications, as it has been cited in studies that utilize this technique to analyze endothelial cell populations in various experimental setups.

What is the significance of using this antibody in research related to angiogenesis?

The pan ECA (MECA-32) antibody is significant in angiogenesis research as it helps identify and characterize endothelial cells, which are essential for the formation of new blood vessels. Its application in studies has provided insights into the mechanisms of macrophage-induced angiogenesis and the role of endothelial cells in this process ().

Santa Cruz Biotechnology, Inc.

10410 Finnell Street

Dallas, Texas 75220

United States

Phone: 1-800-457-3801
831-457-3801

Company Profile

Website: http://www.scbt.com/

(1) Fgfbp1 promotes blood-brain barrier development by regulating collagen IV deposition and maintaining Wnt/β-catenin signalingDevelopment (Cambridge, England)August 24, 2020Cottarelli A, Corada M, Beznoussenko GV, Mironov AA, Globisch MA, Biswas S, Huang H, Dimberg A, Magnusson PU, Agalliu D, et al.

(2) Sulforaphane enriched transcriptome of lung mitochondrial energy metabolism and provided pulmonary injury protection via Nrf2 in miceToxicology and applied pharmacologyFebruary 1, 2019Cho HY, Miller-DeGraff L, Blankenship-Paris T, Wang X, Bell DA, Lih F, Deterding L, Panduri V, Morgan DL, Yamamoto M, et al.used to detect secreted mucin 5, subtypes A and C (Muc5AC) in BAL (20 μl) using a capture antibody (sc-19603, Santa Cruz Biotechnology, Santa Cruz, CA) and a detection antibody (Clone 45M1, Thermo Scientific,

(3) Activation of Ras in the Vascular Endothelium Induces Brain Vascular Malformations and Hemorrhagic StrokeCell reportsSeptember 11, 2018Li QF, Decker-Rockefeller B, Bajaj A, Pumiglia K.

(4) Inverse correlation between vascular endothelial growth factor back-filtration and capillary filtration pressuresNephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal AssociationSeptember 1, 2018Kuppe C, Rohlfs W, Grepl M, Schulte K, Veron D, Elger M, Sanden SK, Saritas T, Andrae J, Betsholtz C, et al.

(5) Eradication of Tumors through Simultaneous Ablation of CD276/B7-H3-Positive Tumor Cells and Tumor VasculatureCancer cellApril 10, 2017Seaman S, Zhu Z, Saha S, Zhang XM, Yang MY, Hilton MB, Morris K, Szot C, Morris H, Swing DA, et al.,Santa Cruz Biotechnology,Cat# sc-23876 Rat Anti-Mouse pan ECA (clone: MECA-32),Santa Cruz Biotechnology,Cat# sc-19603 Human IgG1 Lambda-UNLB,Southern Biotech,Cat# 0151L-01 "Goat Anti-FITC/Oregon Green, Alexa Fluor 488",ThermoFisher,Cat#

(6) Sexual dimorphism in activation of placental autophagy in obese women with evidence for fetal programming from a placenta-specific mouse modelAutophagyMay 3, 2016Muralimanoharan S, Gao X, Weintraub S, Myatt L, Maloyan A.

(7) Tumor-homing peptides as tools for targeted delivery of payloads to the placentaScience advancesMay 1, 2016King A, Ndifon C, Lui S, Widdows K, Kotamraju VR, Agemy L, Teesalu T, Glazier JD, Cellesi F, Tirelli N, et al.spectrum screening (1:50; Z0622, Dako); rat anti-mouse pan endothelial cell antigen MECA-32 (1:50; sc-19603, Santa Cruz Biotechnology); rabbit anti-human calreticulin (1:100; ab2907, Abcam); rabbit anti-mouse

(8) Formation of fenestrae in murine liver sinusoids depends on plasmalemma vesicle-associated protein and is required for lipoprotein passagePloS oneJanuary 1, 2014Herrnberger L, Hennig R, Kremer W, Hellerbrand C, Goepferich A, Kalbitzer HR, Tamm ER.

(9) Tanycytic VEGF-A boosts blood-hypothalamus barrier plasticity and access of metabolic signals to the arcuate nucleus in response to fastingCell metabolismApril 2, 2013Langlet F, Levin BE, Luquet S, Mazzone M, Messina A, Dunn-Meynell AA, Balland E, Lacombe A, Mazur D, Carmeliet P, et al.

(10) Constitutive overexpression of Norrin activates Wnt/β-catenin and endothelin-2 signaling to protect photoreceptors from light damageNeurobiology of diseaseFebruary 1, 2013Braunger BM, Ohlmann A, Koch M, Tanimoto N, Volz C, Yang Y, Bösl MR, Cvekl A, Jägle H, Seeliger MW, et al.

(11) Hyaluronan impairs vascular function and drug delivery in a mouse model of pancreatic cancerGutJanuary 1, 2013Jacobetz MA, Chan DS, Neesse A, Bapiro TE, Cook N, Frese KK, Feig C, Nakagawa T, Caldwell ME, Zecchini HI, et al.

(12) Exacerbated airway toxicity of environmental oxidant ozone in mice deficient in Nrf2Oxidative medicine and cellular longevityJanuary 1, 2013Cho HY, Gladwell W, Yamamoto M, Kleeberger SR.each well of an ELISA plate containing a polyclonal anti-Muc5AC capture antibody (1 : 40 dilution; sc19603, Santa Cruz Biotechnology Inc., Santa Cruz, CA, USA) in pH 9.5 bicarbonate-carbonate coating buffer

(13) The role of plasmalemma vesicle-associated protein (PLVAP) in endothelial cells of Schlemm's canal and ocular capillariesExperimental eye researchDecember 1, 2012Herrnberger L, Ebner K, Junglas B, Tamm ER.

(14) Lack of endothelial diaphragms in fenestrae and caveolae of mutant Plvap-deficient miceHistochemistry and cell biologyNovember 1, 2012Herrnberger L, Seitz R, Kuespert S, Bösl MR, Fuchshofer R, Tamm ER.

(15) Endothelial cells provide an instructive niche for the differentiation and functional polarization of M2-like macrophagesBloodOctober 11, 2012He H, Xu J, Warren CM, Duan D, Li X, Wu L, Iruela-Arispe ML.histologic tissue. Matrigel sections were immunostained for anti–MECA-32 (Santa Cruz Biotechnology; sc-19603) and anti-DsRed (MBL; PM005) antibodies and scanned by a confocal microscope (Carl Zeiss; LSM710) at

(16) Effects of increased renal tubular vascular endothelial growth factor (VEGF) on fibrosis, cyst formation, and glomerular diseaseThe American journal of pathologyNovember 1, 2009Hakroush S, Moeller MJ, Theilig F, Kaissling B, Sijmonsma TP, Jugold M, Akeson AL, Traykova-Brauch M, Hosser H, Hähnel B, et al.

(17) Increased fibrovascular invasion of subcutaneous polyvinyl alcohol sponges in SPARC-null miceWound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair SocietyNovember 1, 2001Bradshaw AD, Reed MJ, Carbon JG, Pinney E, Brekken RA, Sage EH.

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pan ECA (MECA-32) Antibody

pan ECA (MECA-32) Antibody from Santa Cruz Biotechnology, Inc.

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Santa Cruz Biotechnology, Inc.

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pan ECA (MECA-32) Antibody from Santa Cruz Biotechnology, Inc.

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