Human Phospho-FGFR1-4 (Y653/Y654) Antibody AF3285 from R&D Systems, a Bio-Techne Brand

Product Specs
ItemHuman Phospho-FGFR1-4 (Y653/Y654) Antibody
CompanyR&D Systems, a Bio-Techne Brand
Price $399.00Supplier Page View Company Product Page
Catalog NumberAF3285
ApplicationsImmunoprecipitation,Western Blot,Immunocytochemistry,Immunocytochemistry/ Immunofluorescence
ReactivityHuman,Mouse,Xenograft
Conjugate/TagUnconjugated
HostRabbit
Quantity50 ug (also 25 ug)
IsotypeIgG
FormatLyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS
TargetFGFR1-4
ClonalityPolyclonal
Modificationsp tyr654
ImmunogenPhosphopeptide containing human FGF R1 Y653/Y654 sites
ConcentrationLYOPH
PurityAntigen Affinity-purified
Antibody TypePrimary Antibodies
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution
NCBI Full Gene Namefibroblast growth factor receptor 4
NCBI Gene AliasesCD334, JTK2, TKF

Specifications/Features

Available conjugates: Unconjugated

Add to Compare List

R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) FGFR2 is a Candidate Immune-Associated Marker of Diabetic Foot Ulcer That Promotes Keratinocyte Function by Activating the PI3K/Akt and MAPK PathwaysMediators InflammApril 15, 2026Hailan Chen, Hongfei Sang, Yi Shi, Jie Pan, Chuang Zhang, Fengrui Lei(1:1000, ab170099, Abcam), anti‐p‐p38 antibody (1:1000, ab178867, Abcam), anti‐p‐FGFR2 antibody (1:1000, AF3285, R&D Systems, Inc., Minneapolis, MN, USA), anti‐FGFR substrate 2 (FRS2) antibody (1:1000, MAB4069, R&D Systems

(2) Transferrin receptor 1 promotes the fibroblast growth factor receptor-mediated oncogenic potential of diffused-type gastric cancerOncogeneApril 1, 2022Shirakihara T, Yamaguchi H, Kondo T, Yashiro M, Sakai R.

(3) Preclinical characterization of bemarituzumab, an anti-FGFR2b antibody for the treatment of cancermAbsJanuary 1, 2021Xiang H, Chan AG, Ahene A, Bellovin DI, Deng R, Hsu AW, Jeffry U, Palencia S, Powers J, Zanghi J, et al.loaded in each lane. Primary antibodies included anti-phospho-FGFR1-4 (Y653/Y654) (R&D Systems; Catalog #AF3285), anti-phospho-FRS2 Y436 (R&D Systems; Catalog #AF5126), anti-FRS2 (clone 462910) (R&D Systems; Catalog

(4) FGF11 influences 3T3-L1 preadipocyte differentiation by modulating the expression of PPARγ regulatorsFEBS open bioApril 1, 2019Lee KW, Jeong JY, An YJ, Lee JH, Yim HS.Cambridge, MA, USA), FGFR1 (#9740; Cell Signaling Technology, Beverly, MA, USA), phospho Y653/Y654 FGFR1‐4 (AF3285; R&D Systems, Minneapolis, MN, USA), FGFR2 (ab109372; Abcam), FGFR3 (ab133644; Abcam), and FGFR4 (ab119378;

(5) FGFR2 amplification is predictive of sensitivity to regorafenib in gastric and colorectal cancers in vitroMolecular oncologyJune 1, 2018Cha Y, Kim HP, Lim Y, Han SW, Song SH, Kim TY.

(6) Gambogenic acid inhibits fibroblast growth factor receptor signaling pathway in erlotinib-resistant non-small-cell lung cancer and suppresses patient-derived xenograft growthCell death & diseaseFebruary 15, 2018Xu L, Meng X, Xu N, Fu W, Tan H, Zhang L, Zhou Q, Qian J, Tu S, Li X, et al.

(7) Basic Fibroblast Growth Factor Inhibits Apoptosis and Promotes Proliferation of Adipose-Derived Mesenchymal Stromal Cells Isolated from Patients with Type 2 Diabetes by Reducing Cellular Oxidative StressOxidative medicine and cellular longevityJanuary 1, 2017Nawrocka D, Kornicka K, Szydlarska J, Marycz K.

(8) Overexpression of FGFR2 contributes to inherent resistance to MET inhibitors in MET-amplified patient-derived gastric cancer xenograftsOncology lettersOctober 1, 2015Liu K, Song X, Zhu M, Ma H.with monoclonal phosphorylated (p)-MET (1:1,000; cat. no. 3126), polyclonal p-FGFR2 (1:1,000; cat no. af3285; R&D Systems, Inc., Minneapolis, MN, USA), monoclonal MET (1:1,000; cat. no. 4560) and monoclonal FGFR2

(9) FGFR2-amplified gastric cancer cell lines require FGFR2 and Erbb3 signaling for growth and survivalCancer researchApril 1, 2008Kunii K, Davis L, Gorenstein J, Hatch H, Yashiro M, Di Bacco A, Elbi C, Lutterbach B.

Be the First to Write a Review!

Phospho-FGFR1-4 (Y653/Y654) Antibody

Phospho-FGFR1-4 (Y653/Y654) Antibody

Phospho-FGFR1-4 (Y653/Y654) Antibody

Phospho-FGFR1-4 (Y653/Y654) Antibody

Human Phospho-FGFR1-4 (Y653/Y654) Antibody from R&D Systems, a Bio-Techne Brand

Specifications/Features

R&D Systems, a Bio-Techne Brand

Citations (9)

Reviews

Human Phospho-FGFR1-4 (Y653/Y654) Antibody from R&D Systems, a Bio-Techne Brand

About Biocompare

Advertise with Us

Specialized Search Tools

Site Map