ARID1B (KMN1) Antibody sc-32762 from Santa Cruz Biotechnology, Inc.

Product Specs
ItemARID1B (KMN1) Antibody
CompanySanta Cruz Biotechnology, Inc.
Price $316.00Supplier Page View Company Product Page
Catalog Numbersc-32762
Antibody TypePrimary Antibodies
NCBI Gene AliasesBAF250B, CSS1, mKIAA1235, 9330189K18Rik, OSA2, P250R, B230217J03Rik, DAN15, ELD/OSA1, BRIGHT, SMARCF2, MRD12, 6A3-5, Ardi1b, 8030481M12
CloneKMN1
Quantity200 µg/ml
ApplicationsWB, IP
Reactivitymouse, rat, human
Conjugate/TagUnconjugated
ClonalityMonoclonal
Hostmouse
FormatPurified
NCBI Full Gene NameAT rich interactive domain 1B (SWI-like), AT-rich interaction domain 1B
TargetARID1B
IsotypeIgG1

Questions and Answers

Can this antibody be used for studying ARID1B in mouse models?

Yes, the ARID1B (KMN1) Antibody has been shown to work effectively in mouse models, as indicated by its use in various studies, including those examining chromatin remodeling complexes and their roles in development and disease.

What applications has this antibody been cited in?

The ARID1B (KMN1) Antibody has been cited in applications such as Western Blotting (WB) and Immunoprecipitation (IP), demonstrating its utility in analyzing protein expression and interactions in various experimental setups.

Is there any evidence of this antibody being used in cancer research?

Yes, the ARID1B (KMN1) Antibody has been referenced in studies related to cancer, particularly in the context of ARID1A mutations in ovarian cancer, where it was used to investigate the role of chromatin remodeling in tumor progression and response to therapies.

How does this antibody contribute to understanding chromatin dynamics?

The ARID1B (KMN1) Antibody has been utilized in research that explores the dynamics of chromatin remodeling complexes, such as the SWI/SNF complex, which are crucial for gene regulation and cellular differentiation, as highlighted in studies focusing on neural development and cancer biology.

Santa Cruz Biotechnology, Inc.

10410 Finnell Street

Dallas, Texas 75220

United States

Phone: 1-800-457-3801
831-457-3801

Company Profile

Website: http://www.scbt.com/

(1) β-catenin functions as a molecular adapter for disordered cBAF interactionsMolecular CellAugust 21, 2025Yuen San Chan, Qinyu Gao, Sarah A. Robinson, Wenzhi Wang, Ruzena Filandrova, Lisa-Maria Weinhold, Mario Loeza Cabrera, Miao Zhang, Chandra Shekar R. Ambati, Antonio M. Lerario, et al.(IP),Santa Cruz Biotechnology,"Cat# sc-32761, RRID:AB_673396" ARID1B (WB),Santa Cruz Biotechnology,"Cat# sc-32762, RRID:AB_2060367" DPF1 (WB),Proteintech,"Cat# 21769-1-AP, RRID:AB_3085672" DPF2 (WB),Proteintech,"Cat#

(2) Armadillo domain of ARID1A directly interacts with DNA-PKcs to couple chromatin remodeling with nonhomologous end joining (NHEJ) pathwayNucleic Acids ResMarch 13, 2025Shin-Ichiro Kanno, Takayasu Kobayashi, Reiko Watanabe, Akihiro Kurimasa, Kozo Tanaka, Akira Yasui, Ayako Uiperformed as described previously [25]. The following antibodies were used: anti-ARID1B (Santa Cruz, sc-32762), anti-VIRMA (25712-1-AP, Proteintech), anti-DDX1 (ab70252, abcam), anti-RTCB (A305-079-M, Betyl), anti-FAM98A

(3) ARID1A loss derepresses a group of human endogenous retrovirus-H loci to modulate BRD4-dependent transcriptionNature communicationsJune 17, 2022Yu C, Lei X, Chen F, Mao S, Lv L, Liu H, Hu X, Wang R, Shen L, Zhang N, et al.

(4) Inability to switch from ARID1A-BAF to ARID1B-BAF impairs exit from pluripotency and commitment towards neural crest formation in ARID1B-related neurodevelopmental disordersNature communicationsNovember 9, 2021Pagliaroli L, Porazzi P, Curtis AT, Scopa C, Mikkers HMM, Freund C, Daxinger L, Deliard S, Welsh SA, Offley S, et al.ARID1B-BAF. Methods Antibodies ARID1B ChIP-Seq: Abcam ab57461. ARID1B western blot: Santa-Cruz sc-32762 and Abcam ab57461. ARID1A ChIP-Seq: GeneTex GTX129433. ARID1A western blot: Cell Signaling Technologies

(5) ARID2 Deficiency Correlates with the Response to Immune Checkpoint Blockade in MelanomaThe Journal of investigative dermatologyJune 1, 2021Fukumoto T, Lin J, Fatkhutdinov N, Liu P, Somasundaram R, Herlyn M, Zhang R, Nishigori C.

(6) Nuclear isoform of FGF13 regulates post-natal neurogenesis in the hippocampus through an epigenomic mechanismCell reportsMay 18, 2021Yang QQ, Zhai YQ, Wang HF, Cai YC, Ma XY, Yin YQ, Li YD, Zhou GM, Zhang X, Hu G, et al.

(7) ARID1A loss in neuroblastoma promotes the adrenergic-to-mesenchymal transition by regulating enhancer-mediated gene expressionScience advancesJuly 1, 2020Shi H, Tao T, Abraham BJ, Durbin AD, Zimmerman MW, Kadoch C, Look AT.

(8) HDAC6 Inhibition Synergizes with Anti-PD-L1 Therapy in ARID1A-Inactivated Ovarian CancerCancer researchNovember 1, 2019Fukumoto T, Fatkhutdinov N, Zundell JA, Tcyganov EN, Nacarelli T, Karakashev S, Wu S, Liu Q, Gabrilovich DI, Zhang R.rabbit anti-ARID1B (Cell Signaling, Cat. No: 92964, 1:1000), mouse anti-ARID1B (Santa Cruz, Cat. No: sc-32762, 1:1000), mouse anti-β-actin (Sigma-Aldrich, Cat. No: A5441, 1:10,000), mouse anti-FLAG (Sigma-Aldrick,

(9) ARID1A and PI3-kinase pathway mutations in the endometrium drive epithelial transdifferentiation and collective invasionNature communicationsAugust 7, 2019Wilson MR, Reske JJ, Holladay J, Wilber GE, Rhodes M, Koeman J, Adams M, Johnson B, Su RW, Joshi NR, et al.(9585, Cell Signaling); 1:1000 Snail (3879, Cell Signaling); 1:1000 Twist1 (T6451, Sigma); 1:100 ARID1B (sc-32762, Santa Cruz); 1:1000 Brg1 (ab110641, Abcam); 1:1000 BRM (11966, Cell Signaling); 1:100 ARID1A (PSG3)

(10) ARID1A loss impairs enhancer-mediated gene regulation and drives colon cancer in miceNature geneticsFebruary 1, 2017Mathur R, Alver BH, San Roman AK, Wilson BG, Wang X, Agoston AT, Park PJ, Shivdasani RA, Roberts CW.

(11) Suppression of the SWI/SNF Component Arid1a Promotes Mammalian RegenerationCell stem cellApril 7, 2016Sun X, Chuang JC, Kanchwala M, Wu L, Celen C, Li L, Liang H, Zhang S, Maples T, Nguyen LH, et al.

(12) Transcription factor MITF and remodeller BRG1 define chromatin organisation at regulatory elements in melanoma cellseLifeMarch 24, 2015Laurette P, Strub T, Koludrovic D, Keime C, Le Gras S, Seberg H, Van Otterloo E, Imrichova H, Siddaway R, Aerts S, et al.

(13) Expanding the phenotypic spectrum of ARID1B-mediated disorders and identification of altered cell-cycle dynamics due to ARID1B haploinsufficiencyOrphanet journal of rare diseasesMarch 27, 2014Sim JC, White SM, Fitzpatrick E, Wilson GR, Gillies G, Pope K, Mountford HS, Torring PM, McKee S, Vulto-van Silfhout AT, et al.

(14) Kinetic analysis of npBAF to nBAF switching reveals exchange of SS18 with CREST and integration with neural developmental pathwaysThe Journal of neuroscience : the official journal of the Society for NeuroscienceJune 19, 2013Staahl BT, Tang J, Wu W, Sun A, Gitler AD, Yoo AS, Crabtree GR.Santa Cruz Biotechnology; W, 1:3k), mouse anti-BAF250a (Santa Cruz Biotechnology; W, 1:1k), mouse anti-BAF250b (SC32762; Santa Cruz Biotechnology; W, 1:6k), mouse anti-BRM (Santa Cruz Biotechnology; W, 1:2k), rabbit anti-BAF53a

(15) BAF complexes facilitate decatenation of DNA by topoisomerase IIαNatureMay 30, 2013Dykhuizen EC, Hargreaves DC, Miller EL, Cui K, Korshunov A, Kool M, Pfister S, Cho YJ, Zhao K, Crabtree GR.

(16) ARID1a-DNA interactions are required for promoter occupancy by SWI/SNFMolecular and cellular biologyJanuary 1, 2013Chandler RL, Brennan J, Schisler JC, Serber D, Patterson C, Magnuson T.standard procedures and the following antibodies: ARID1a (A301-040A or A301041A; Bethyl Labs), ARID1b (sc-32762; Santa Cruz), ARID2 (A302-230A; Bethyl Labs), BRG1 (sc-17796; Santa Cruz), BRM (sc-6450; Santa Cruz), INI1/SNF5

(17) Essential role of ARID2 protein-containing SWI/SNF complex in tissue-specific gene expressionThe Journal of biological chemistryFebruary 10, 2012Xu F, Flowers S, Moran E.

(18) Dynamics of expression of ARID1A and ARID1B subunits in mouse embryos and in cells during the cell cycleCell and tissue researchJuly 1, 2011Flores-Alcantar A, Gonzalez-Sandoval A, Escalante-Alcalde D, Lomelí H.

(19) A balanced translocation t(6;14)(q25.3;q13.2) leading to reciprocal fusion transcripts in a patient with intellectual disability and agenesis of corpus callosumCytogenetic and genome researchJanuary 1, 2011Backx L, Seuntjens E, Devriendt K, Vermeesch J, Van Esch H.

(20) Mammalian SWI/SNF--a subunit BAF250/ARID1 is an E3 ubiquitin ligase that targets histone H2BMolecular and cellular biologyApril 1, 2010Li XS, Trojer P, Matsumura T, Treisman JE, Tanese N.

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ARID1B (KMN1) Antibody

ARID1B (KMN1) Antibody from Santa Cruz Biotechnology, Inc.

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Questions and Answers

Santa Cruz Biotechnology, Inc.

Citations (20)

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ARID1B (KMN1) Antibody from Santa Cruz Biotechnology, Inc.

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