ULK1 (D9D7) Rabbit mAb 6439S from Cell Signaling Technology

Product Specs
ItemULK1 (D9D7) Rabbit mAb
CompanyCell Signaling Technology
Price $339.00 Inquire
Catalog Number6439S
Quantity100 µl
ApplicationsW, IP
ReactivityH, Mk
ClonalityMonoclonal
TargetULK1
HostRabbit
NCBI Gene AliasesATG1, ATG1A, UNC51, Unc51.1, hATG1
NCBI Full Gene Nameunc-51 like autophagy activating kinase 1
Research AreaAutophagy
IsotypeIgG
CloneD9D7
Molecular Weight150

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Cell Signaling Technology

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Danvers, Massachusetts 01923

United States

Phone: 877-616-CELL
Phone: 978-867-2388
Fax: 866-432-6112
Fax: 978-867-2488

Company Profile

Website: http://www.cellsignal.com/

Website: Technical Support

(1) mTOR inhibition in Q175 Huntington’s disease model mice facilitates neuronal autophagy and mutant huntingtin clearanceElifeMay 20, 2025Philip Stavrides, Chris N Goulbourne, James Peddy, Chunfeng Huo, Mala Rao, Vinod Khetarpal, Deanna M Marchionini, Ralph A Nixon, Dun-Sheng Yang,Cell Signaling Technology,Cat# 5364; RRID:AB_10694233,WB: 1:1000 Antibody,ULK1,Cell Signaling Technology,Cat# 6439; RRID:AB_11178933,WB: 1:500 Antibody,p-ULK S757,Cell Signaling Technology,Cat# 6888; RRID:AB_10829226,WB:

(2) Neuroprotective Effect of Melatonin in a Neonatal Hypoxia-Ischemia Rat Model Is Regulated by the AMPK/mTOR PathwayJournal of the American Heart AssociationOctober 1, 2024Nacarkucuk E, Bernis ME, Bremer AS, Grzelak K, Zweyer M, Maes E, Burkard H, Sabir H.,Cell Signaling Technology,Rabbit,1:1000,D14E12,65 Western blot,HIF1α,GTX127309,GeneTex,Rabbit,1:500,…,93 Western blot,ULK‐1,6439,Cell Signaling Technology,Rabbit,1:500,D9D7,113 Western blot,Phospho ULK‐1 S555,58 695,Cell Signaling

(3) The glycoprotein 5 of porcine reproductive and respiratory syndrome virus stimulates mitochondrial ROS to facilitate viral replicationmBioDecember 4, 2023Shuang Zhang, Lei Zeng, Bing-Qian Su, Guo-Yu Yang, Jiang Wang, Sheng-Li Ming, Bei-Bei Chuanti-AMPK (#2532S), anti-p-AMPK (#50,081 s), anti-mTOR (#2983T), anti-p-mTOR (#5536T), anti-ULK1 (#6439S), anti-p-ULK1 (ser757) (#14,202T), anti-p-ULK1(ser555) (#5869T), anti-p-DRP1 (#3455S), anti-EGFP (#2956),

(4) A novel role for Helicobacter pylori cytotoxin-associated gene A in negative regulation of autophagy in human gastric cellsBMC GastroenterologySeptember 22, 2023Akihiko Sakatani, Yoshito Hayashi, Hirotsugu Saiki, Minoru Kato, Ryotaro Uema, Takanori Inoue, Keiichi Kimura, Shunsuke Yoshii, Yoshiki Tsujii, Shinichiro Shinzaki, et al.BECN1 (#3495), microtubule-associated proteins 1A/1B light chain 3A (LC3; #2775), P62(#5114), ULK1 (#6439) (Cell Signaling Technology, Danvers, MA, USA), and phospho-tyrosine (05–1050; Sigma–Aldrich, Ann Arbor,

(5) Apoptotic and autophagic cell death induced in cervical cancer cells by a dual specific oncolytic adenovirusAnti-Cancer DrugsMarch 1, 2023Shanzhi Li, Zhuoxin Li, Shuang Chen, Yilong Zhu, Yiquan Li, Xunzhe Yin, Xiao Li, Guangze Zhu(CST, #2983, USA), anti-ATG12 (CST, # 4180, USA), anti-ATG5 (CST, # 12994, USA) and anti-ULK1 (CST, # 6439, USA) antibodies at 1:1000 for overnight at 4 °C. After washing, the membrane was incubated with the

(6) Ferroptosis inhibition by lysosome-dependent catabolism of extracellular proteinCell chemical biologyNovember 17, 2022Armenta DA, Laqtom NN, Alchemy G, Dong W, Morrow D, Poltorack CD, Nathanson DA, Abu-Remalieh M, Dixon SJ.RRID:AB_331163" Akt,Cell Signaling Technology,"Cat# 9272, RRID:AB_329827" ULK1,Cell Signaling Technology,"Cat# 6439, RRID:AB_11178933" CTSB,Cell Signaling Technology,"Cat# 31718, RRID:AB_2687580" CTSD,Cell Signaling Technology

(7) Mycobacterium tuberculosis Rv0790c inhibits the cellular autophagy at its early stage and facilitates mycobacterial survivalFrontiers in Cellular and Infection MicrobiologyNovember 9, 2022Jun Fang, Chunsheng Dong, Sidong Xionganti-mTOR (CST, 2983), anti-Phospho-P70S6K (Thr389, CST, 9234), anti-p70S6K (CST, 2708), anti-ULK (CST, 6439), anti-phospho-ULK (Ser757, CST, 14202), anti-GAPDH (ABclonal, A19056), anti-GroEL (Abcam, ab82592),

(8) GNIP1 functions both as a scaffold protein and an E3 ubiquitin ligase to regulate autophagy in lung cancerCell communication and signaling : CCSAugust 30, 2022Zhou F, Liu Y, Ai W, Wang Y, Gan M, Jiang Q, Han T, Wang JB.SQSTM1/p62 (Proteintech; TA502127), BECN1 (Proteintech; 11,306–1-AP), ULK1 (Cell Signaling Technology; 6439), HA-tag (Thermo Fisher Scientific; 26,183), GFP (Proteintech; 66,002-1-lg), UB antibody (Proteintech;

(9) CHK2 Promotes Metabolic Stress-Induced Autophagy through ULK1 PhosphorylationAntioxidants (Basel, Switzerland)June 14, 2022Guo R, Wang SS, Jiang XY, Zhang Y, Guo Y, Cui HY, Guo QQ, Cao L, Xie XC.indicated primary antibodies. Antibody information and usage are as follows: rabbit anti-ULK1 (D9D7) mAb #6439 (1:1000, CST), rabbit anti-phospho-ULK1 (D1H4) mAb#5869 (S555 (mouse), S556 (human)) (1:1000, CST),

(10) FAIM regulates autophagy through glutaminolysis in lung adenocarcinomaAutophagyJune 1, 2022Han T, Wang P, Wang Y, Xun W, Lei J, Wang T, Lu Z, Gan M, Zhang W, Yu B, et al.Proteintech (18725-1-AP). The ULK1 and p-ULK1 (Ser757) were ordered from Cell Signaling Technology (6439, 14202). The ULK1 antibody purchased from Cell Signaling Technology (6439) was used for immunoprecipitation.

(11) HNF4A and GATA6 Loss Reveals Therapeutically Actionable Subtypes in Pancreatic CancerSSRN Electronic JournalMarch 31, 2022Holly Brunton et al.Cell signaling Technology Cat# 3050; RRID:AB_823559 ULK1 (D9D7) Rabbit mAB Cell signaling Technology Cat# 6439; RRID:AB_11178933 ATF-3 Cell signaling Technology Cat# 33593; RRID:AB_2799039 LC3B Cell signaling Technology

(12) Cell immortalization facilitates prelamin A clearance by increasing both cell proliferation and autophagic fluxAgingMarch 8, 2022González-Blanco C, Marqués P, Burillo J, Jiménez B, García G, Benito M, Guillén C.anti-Phospho-p70S6K (Thr389) (#9205), anti-p70S6K (#9202), anti-Phospho-ULK1 (Ser757) (#14202), anti-ULK1 (#6439), anti-phospho-PERK (Thr980) (#3179), anti-PERK (#3192), anti-Phospho-eIF2-alpha (Ser51) (#9721), anti-eIF2-alpha

(13) African Swine Fever Virus K205R Induces ER Stress and Consequently Activates Autophagy and the NF-κB Signaling PathwayVirusesFebruary 15, 2022Wang Q, Zhou L, Wang J, Su D, Li D, Du Y, Yang G, Zhang G, Chu B.anti-IκBα (4814), anti-p-IκBα (Ser32, 2859), anti-mTOR (2983T), anti-p-mTOR (ser2448, 5536), anti-ULK1 (6439), anti-p-ULK1 (ser555, 5869), anti-p-ULK1 (ser757, 14202), anti-AKT (2920), and anti-p-AKT (Ser473,

(14) Molecular Regulators of Muscle Mass and Mitochondrial Remodeling Are Not Influenced by Testosterone Administration in Young WomenFrontiers in endocrinologyJanuary 1, 2022Horwath O, Moberg M, Hirschberg AL, Ekblom B, Apró W.against androgen receptor (#D6F11XP®), mTOR (#2983), S6K1 (#2708), eEF2 (#2332), AMPK (#2532), ULK1 (#6439), p62 (#8025), LC3B (#2775), Beclin (#3495) and BNIP3 (#44060), were purchased from Cell Signaling Technology

(15) Insulin sensitization causes accelerated sinus nodal dysfunction through autophagic dysregulation in hypertensive miceTranslational and clinical pharmacologyJune 1, 2021Woo M, Kim M.purchased from GeneTex. Beta-actin (#8457), LC3 I & II (#12741), phospho-ULK1 (#12753), and total-ULK1 (#6439) were purchased from Cell Signaling Technology. D-Tat-Beclin-1 was obtained from Calbiochem. Pioglitazone (#E6910)

(16) Administration of quercetin improves mitochondria quality control and protects the neurons in 6-OHDA-lesioned Parkinson's disease modelsAgingApril 20, 2021Wang WW, Han R, He HJ, Li J, Chen SY, Gu Y, Xie C.antibody (catalog no.3504s; CST); phospho-ULK1 antibody (catalog no.5869s; CST); ULk1 antibody (catalog no.6439s; CST), and then followed by horseradish peroxidase-labeled IgG. The membranes were developed using enhanced

(17) TNFAIP8 regulates gastric cancer growth via mTOR‐Akt‐ULK1 pathway and autophagy signalsJournal of Cellular and Molecular MedicineApril 1, 2021Zheng Chen, Jianguo Zhang, Chenyang Dong, Dongsheng Li, Yuehan Yin, Wenhai Yu, Yuezhi Chen1:1000), Akt (#4685, 1:1000), p‐mTOR (#5536, Ser2448,1:1000), p‐ULK1 (#14202, Ser757,1:1000), ULK1 (#6439, 1:1000), and GAPDH (#5147, 1:1000) from Cell Signaling Technology; antibodies against TNFAIP8 (ab251212,

(18) PPARγ/SOD2 Protects Against Mitochondrial ROS-Dependent Apoptosis via Inhibiting ATG4D-Mediated Mitophagy to Promote Pancreatic Cancer ProliferationFrontiers in cell and developmental biologyJanuary 1, 2021Nie S, Shi Z, Shi M, Li H, Qian X, Peng C, Ding X, Zhang S, Lv Y, Wang L, et al.p-mTORSer2448 (1:1,000, Cell Signaling Technology, #5536), ULK1 (1:1,000, Cell Signaling Technology, #6439), p-ULK1Ser317 (1:1,000, Cell Signaling Technology, #12753), S6 (1:1,000, Cell Signaling Technology,

(19) Cockayne syndrome proteins CSA and CSB maintain mitochondrial homeostasis through NAD(+) signalingAging cellDecember 1, 2020Okur MN, Fang EF, Fivenson EM, Tiwari V, Croteau DL, Bohr VA.p‐AMPK (Thr172) (Cell signaling, #2535), pULK1 (Ser555, Cell signaling, #5869), ULK1 (Cell signaling, #6439), p62 (Cell signaling, #39749), β‐actin (Santa Cruz, #sc‐1616), DRP1 (Cell signaling, #8570), p‐DRP‐1

(20) Nicotinamide N-methyltransferase inhibits autophagy induced by oxidative stress through suppressing the AMPK pathway in breast cancer cellsCancer Cell InternationalDecember 1, 2020Haitao Yu, Xi Zhou, Yanzhong Wang, Xucheng Huang, Jun Yang, Jin Zeng, Guoli Li, Xinyou Xie, Jun Zhang(#12741), anti-p-AMPK (T172) (# 2535), anti-AMPK (#2532), anti-p-ULK1 (Ser317) (# 12753), anti-ULK1 (# 6439), anti-β-Actin (# 4970) and goat anti-rabbit (# 7074) and goat anti-mouse (# 7076) HRP-conjugated secondary

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ULK1 (D9D7) Rabbit mAb

ULK1 (D9D7) Rabbit mAb from Cell Signaling Technology

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Cell Signaling Technology

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ULK1 (D9D7) Rabbit mAb from Cell Signaling Technology

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