RagB (D18F3) Rabbit mAb 8150S from Cell Signaling Technology

Product Specs
ItemRagB (D18F3) Rabbit mAb
CompanyCell Signaling Technology
Price $339.00 Inquire
Catalog Number8150S
Quantity100 µl
ApplicationsW, IP
ReactivityH, Mk
ClonalityMonoclonal
TargetRagB
HostRabbit
NCBI Gene AliasesRAGB, bA465E19.1
NCBI Full Gene NameRas related GTP binding B
Research AreaPI3K / Akt Signaling
CloneD18F3
Molecular Weight40

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Cell Signaling Technology

3 Trask Lane

Danvers, Massachusetts 01923

United States

Phone: 877-616-CELL
Phone: 978-867-2388
Fax: 866-432-6112
Fax: 978-867-2488

Company Profile

Website: http://www.cellsignal.com/

Website: Technical Support

(1) FNIP1 Modulates B Cell Receptor Signaling Strength by Coordinating Metabolism During DevelopmentbioRxivApril 1, 2026Heon Park, Ryan Culbert, Dechen Sakya, Raynah R. Silprasert, Brian M. Iritani(2855S), Phospho-GSK-3α/β (Ser21/9)(9327T), Rag and LAMTOR antibody sampler kit (RagA (4357), RagB (8150), RagC (9480), RagD (4470)), Histone H3 (4499P), TFE3 (14779s), TFEB (A303-673A, bethyl lab), α-rabbit

(2) Anabolic Sensitivity in Healthy, Lean, Older Men Is Associated With Higher Expression of Amino Acid Sensors and mTORC1 Activators Compared to YoungJournal of Cachexia, Sarcopenia and MuscleFebruary 1, 2025Oscar Horwath, Marcus Moberg, Nathan Hodson, Sebastian Edman, Mats Johansson, Eva Andersson, Gerrit van Hall, Olav Rooyackers, Andrew Philp, William Apró398,Mouse,SCBT,1:500,TBST 2.5% milk LAT1,sc‐374 232,Mouse,SCBT,1:500,Fluorescent blocking buffer RagB,#8150,Rabbit,CST,1:1000,TBST 2.5% milk LAMP2,Sc‐18 822,Mouse,SCBT,1:1000,TBST 2.5% milk Antibody information. Abbreviations:

(3) Inhibition of lysosome-tethered Ragulator-Rag-3D complex restricts the replication of Enterovirus 71 and Coxsackie A16The Journal of cell biologyDecember 4, 2023Wang X, Hu Z, Zhang W, Wu S, Hao Y, Xiao X, Li J, Yu X, Yang C, Wang J, et al.(Cat #8168; Cell Signaling Technology), LAMTOR1 (Cat #8975S; Cell Signaling Technology), RagB (Cat #8150S, RRID:AB_11178806; Cell Signaling Technology), Enterovirus 71 (VP1; Cat #ab169442; Abcam), Enterovirus

(4) A Rag GTPase dimer code defines the regulation of mTORC1 by amino acidsNature cell biologySeptember 1, 2022Gollwitzer P, Grützmacher N, Wilhelm S, Kümmel D, Demetriades C.(#8054), phospho-ULK1 (Ser757) (#14202), DYKDDDDK (FLAG) tag (#2368), mTOR (#2983), RagA (#4357), RagB (#8150), RagC (#9480), RagD (#4470), FLCN (#3697) and CTSD (#2284) proteins were purchased from Cell Signaling Technology

(5) O-GlcNAc modification of leucyl-tRNA synthetase 1 integrates leucine and glucose availability to regulate mTORC1 and the metabolic fate of leucineNature communicationsMay 25, 2022Kim K, Yoo HC, Kim BG, Kim S, Sung Y, Yoon I, Yu YC, Park SJ, Kim JH, Myung K, et al.(D8H5) (WB dilution 1:1000, Cell signaling, #9480), RagB (D18F3) (WB dilution 1:1000, Cell signaling, #8150), mTOR (7C10) (WB dilution 1:1000, Cell signaling, #2983), Raptor (24C12) (WB dilution 1:1000, Cell signaling

(6) mTORC1 couples cyst(e)ine availability with GPX4 protein synthesis and ferroptosis regulationNature communicationsMarch 11, 2021Zhang Y, Swanda RV, Nie L, Liu X, Wang C, Lee H, Lei G, Mao C, Koppula P, Cheng W, et al.#2845), RagA (1:1000; Cell Signaling Technology, #4357), RagB (1:1000; Cell Signaling Technology, #8150), LAMP2 (1:1000; Cell Signaling Technology, #49067), P-eIF2α (1:1000; Cell Signaling Technology, #3398),

(7) Leucine regulates autophagy via acetylation of the mTORC1 component raptorNature communicationsJune 19, 2020Son SM, Park SJ, Stamatakou E, Vicinanza M, Menzies FM, Rubinsztein DC.rabbit anti-acetylated-Lysine (Ac-K) (#9814, #9441), rabbit anti-RRAGA (#4357), rabbit anti-RRAGB (#8150), rabbit anti-WIPI2 (#8567), and rabbit anti-ATG16L1 (#8089) from Cell Signaling Technology; antimouse

(8) mTORC1 feedback to AKT modulates lysosomal biogenesis through MiT/TFE regulationThe Journal of clinical investigationDecember 2, 2019Asrani K, Murali S, Lam B, Na CH, Phatak P, Sood A, Kaur H, Khan Z, Noë M, Anchoori RK, et al.(catalog 8168, Cell Signaling), 1:1000; RagA (catalog 4357, Cell Signaling), 1:1000; RagB (catalog 8150, Cell Signaling), 1:1000; RagC (catalog 5466, Cell Signaling), 1:1000; LAPTM4B (catalog ABC290, EMD Millipore

(9) Full title: High glucose protects mesenchymal stem cells from metformin-induced apoptosis through the AMPK-mediated mTOR pathwayScientific ReportsDecember 1, 2019Xiao He, Yi Yang, Meng-Wei Yao, Ting-ting Ren, Wei Guo, Ling Li, Xiang Xucleaved Caspase-3 (Cl-Caspase3) (Asp175) (#9664), p-Akt (Ser473) (#4060), p-Akt (Thr308) (#13038), RagB (#8150), LC3B (#3868), β-Actin (#3700) were all purchased from Cell Signaling Technology, Danvers, USA. Real-time

(10) Neuron-Type Specific Loss of CDKL5 Leads to Alterations in mTOR Signaling and Synaptic MarkersMolecular neurobiologyJune 1, 2019Schroeder E, Yuan L, Seong E, Ligon C, DeKorver N, Gurumurthy CB, Arikkath J.(Cell Signaling Technology, 4308), 1:1000 Rag C (Cell Signaling Technology, 5466), 1:1000 Rag B (Cell Signaling Technology, 8150), 1:1000 Rag A (Cell Signaling Technology, 4357), 1:1000 p-TSC2(S939) (Cell Signaling Technology, 3615),

(11) Leucine Signals to mTORC1 via Its Metabolite Acetyl-Coenzyme ACell metabolismJanuary 8, 2019Son SM, Park SJ, Lee H, Siddiqi F, Lee JE, Menzies FM, Rubinsztein DC.,Cell Signaling Technology,#4357; RRID: AB_10545136 Rabbit monoclonal anti-RagB,Cell Signaling Technology,#8150; RRID: AB_11178806 Rabbit monoclonal anti-RagC (D8H5),Cell Signaling Technology,#9480; RRID: AB_10614716 Rabbit

(12) Regulation of Amino Acid Transporters and Sensors in Response to a High protein Diet: A Randomized Controlled Trial in Elderly MenThe journal of nutrition, health & agingJanuary 1, 2019Zeng N, Prodhan U, D'Souza RF, Ramzan F, Mitchell SM, Sharma P, Knowles SO, Roy NC, Sjödin A, Wagner KH, et al.with primary antibodies at 1: 1,000 dilution. The following antibodies were used: LAT1 (#5347), RagB (#8150), RagD (#4470), p70S6K1 (#2708), PRAS40 (#2691), p-p70S6K1Thr421/Ser424 (#9204), p-eIF4ESer209 (#9741),

(13) UBE3A-mediated p18/LAMTOR1 ubiquitination and degradation regulate mTORC1 activity and synaptic plasticityeLifeJuly 18, 2018Sun J, Liu Y, Jia Y, Hao X, Lin WJ, Tran J, Lynch G, Baudry M, Bi X.,Cell Signaling Technology,4357; RRID:AB_10545136,(1:1000) Antibody,anti-RagB (rabbit monoclonal),Cell Signaling Technology,8150; RRID:AB_11178806,(1:1000) Antibody,anti-RagC (rabbit monoclonal),Cell Signaling Technology,5466; RRID:AB_10692651,(1:1000) Antibody,anti-ubiquitin

(14) Arginase 2 Suppresses Renal Carcinoma Progression via Biosynthetic Cofactor Pyridoxal Phosphate Depletion and Increased Polyamine ToxicityCell metabolismJune 5, 2018Ochocki JD, Khare S, Hess M, Ackerman D, Qiu B, Daisak JI, Worth AJ, Lin N, Lee P, Xie H, et al.,Cell Signaling,#3615 tuberin/TSC2,Cell Signaling,#3612 EAAT1,Cell Signaling,#5684 RagB,Cell Signaling,#8150 HSP90,Cell Signaling,#4874S anti-rabbit IgG HRP-linked,Cell Signaling,#7074 anti-mouse IgG HRP-linked,Cell Signaling

(15) Tetraspanin CD63 Bridges Autophagic and Endosomal Processes To Regulate Exosomal Secretion and Intracellular Signaling of Epstein-Barr Virus LMP1Journal of virologyMarch 1, 2018Hurwitz SN, Cheerathodi MR, Nkosi D, York SB, Meckes DG Jr.Cell Signaling), G␤L (3274; Cell Signaling), LAMTOR1 (8975; Cell Signaling), RagA (4357; Cell Signaling), RagB (8150; Cell Signaling), RagC (5466; Cell Signaling), RagD (4470; Cell Signaling), phospho-p70 S6 kinase Thr389

(16) SZT2 dictates GATOR control of mTORC1 signallingNatureMarch 16, 2017Peng M, Yin N, Li MO.(#13038), pAkt (S473) (#4060), AKT (4691), p4E-BP1 (S65) (#9456), 4E-BP1 (#9644), RagA (#4357), RagB (#8150), RagC (#9480), Sestrin2 (#8487), MIOS (#13557), EEA1 (#3288, used for immunofluorescence (IF)), Lamp1

(17) Recurrent Mutations in the MTOR Regulator RRAGC in Follicular LymphomaClinical Cancer ResearchNovember 1, 2016Zhang Xiao Ying et al.(#A544) was from Sigma Aldrich. Antibodies against RRAGC (#3360), anti-folliculin (#3697), anti-RRAGB (#8150), anti-RRAGA (#4357), anti-S6Kinase (#9202) and anti-pS6-Kinase-Thr 389 (#9205) were purchased from

(18) Recurrent mutations in the MTOR regulator RRAGC in follicular lymphomaClin. Cancer Res.June 7, 2016Zhang Xiao Ying, Meiyan Jin, Luke F. Peterson, Denzil Bernard, Kamlai Saiya-Cork, Mehmet Yildiz, Shaomeng Wang, Mark S. Kaminski, Alfred E. Chang, Daniel J. Klionsky, et al.(#A544) was from Sigma Aldrich. Antibodies against RRAGC (#3360), anti-folliculin (#3697), anti-RRAGB (#8150), anti-RRAGA (#4357), anti-S6Kinase (#9202) and anti-pS6-Kinase-Thr 389 (#9205) were purchased from

(19) Amino Acid-Dependent mTORC1 Regulation by the Lysosomal Membrane Protein SLC38A9Molecular and cellular biologyJuly 1, 2015Jung J, Genau HM, Behrends C.anti-LAMP2 (ab25631; Abcam); anti-mTOR (2983; Cell Signaling); anti-myc (sc-40; Santa Cruz); anti-RRAGB (8150; Cell Signaling); antiRRAGA, anti-RRAGC, and anti-LAMTOR2 (Rag and LAMTOR antibody sampler kit; 8665;

(20) Sestrin2 inhibits mTORC1 through modulation of GATOR complexesScientific reportsMarch 30, 2015Kim JS, Ro SH, Kim M, Park HW, Semple IA, Park H, Cho US, Wang W, Guan KL, Karin M, et al.were obtained from Santa Cruz Biotechnology, Inc. mTOR (2983), phospho-S6K (9234), MIOS (13557), RagB (8150), phospho-S6 (2211) and phospho-4E-BP1 (2855) antibodies were purchased from Cell Signaling Technology,

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RagB (D18F3) Rabbit mAb

RagB (D18F3) Rabbit mAb from Cell Signaling Technology

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Cell Signaling Technology

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RagB (D18F3) Rabbit mAb from Cell Signaling Technology

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